Month: November 2022

Zhao, Shen published the artcileAcetalization of aldehydes and ketones over H₄[SiW₁₂O₄₀] and H₄[SiW₁₂O₄₀]/SiO₂, Formula: C8H14O2, the publication is Catalysis Science & Technology (2014), 4(8), 2618-2625, database is CAplus.

H₄[SiW₁₂O₄₀] (H-SiW₁₂) is demonstrated to be able to efficiently catalyze the acetalization of aldehydes and ketones with ethylene glycol and 1,3-propanediol. Nevertheless, the possible leaching and the recycling of H-SiW₁₂ are two major disadvantages that largely restrict its further application in industry. Moreover, H₄[SiW₁₂O₄₀] tends to deactivate strong proton sites due to the small surface area of 10 m² g^-1. Due to interactions with surface silanol groups, the proton sites of polyoxometalates (POMs) on SiO₂ are less susceptible to deactivation. As such, immobilization of H₄[SiW₁₂O₄₀] onto SiO₂ leads to the heterogeneous catalyst H₄[SiW₁₂O₄₀]/SiO₂ (H-SiW₁₂/SiO₂), which can catalyze the acetalization of aldehydes and ketones with ethylene glycol and 1,3-propanediol selectively and efficiently without the need of a drying agent. The acetalization process can proceed smoothly at a relatively low temperature under solvent-free conditions. The catalyst of H₄[SiW₁₂O₄₀]/SiO₂ can be recycled at least ten times without an obvious decrease in its catalytic activity. As far as we know, the TONs of the H-SiW₁₂/SiO₂-catalyzed acetalization of cyclohexanone with ethylene glycol, and benzaldehyde with 1,3-propanediol are the highest reported so far.

Catalysis Science & Technology published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C18H28N2O7, Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Pouretedal, Hamid Reza published the artcileA simple method for predicting the gas-chromatographic retention indices of phenolic derivatives, Formula: C11H14O4, the publication is Journal of the Iranian Chemical Society, database is CAplus.

A simple approach is proposed to predict the gas-chromatog. retention indexes in nonpolar columns for a wide range of phenolic derivatives, through their mol. structures and independent of temperature data and active phase of column. The new model is based on the number of atoms and some structural moieties which depend on intra- and intermol. interactions. The present method can be easily applied for many kinds of phenolic compounds containing different substituents without using special computer codes, which need expert users. A big pool of the exptl. data (335 compounds) of retention indexes is used to construct the new model (80% for training set and 20% for test set). Different statistical parameters including the coefficient of determination, R2 (= 0.9482), root mean squared error, RMSE (= 89.01), and mean absolute percent error, MAPE (= 4.494), are used to investigate the reliability of the model, through both internal and external validation techniques.

Journal of the Iranian Chemical Society published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Islam, Tofazzal Md. published the artcileHost-specific plant signal and G-protein activator, mastoparan, trigger differentiation of zoospores of the phytopathogenic oomycete Aphanomyces cochlioides, COA of Formula: C16H10O5, the publication is Plant and Soil (2003), 255(1), 131-142, database is CAplus.

We found that a gradient of a host-specific attractant, cochliophilin A (5-hydroxy-6,7-methylenedioxyflavone) isolated from the roots of spinach triggered encystment followed by germination of zoospores of Aphanomyces cochlioides at a concentration less than micromolar order. This compound did not affect the growth and reproduction of this phytopathogen up to 10^-6 M concentration in the culture medium. We also observed that mastoparan, an activator of heterotrimeric G-protein could inhibit the motility of zoospores and then strikingly effect encystment followed by 60-80% germination of cysts. Concomitant application of cochliophilin A and mastoparan showed stronger encystment followed by 100% germination of cysts. In addition, we have observed that chems. interfering with phospholipase C activity (neomycin) and Ca²⁺ influx/release (EGTA and loperamide) suppress cochliophilin A or mastoparan induced encystment and germination. These results suggest that G-protein mediated signal transduction mechanism may be involved in the differentiation of the A. cochlioides zoospores. This is the first report on the differentiation of oomycete zoospores initiated by a host-specific plant signal or a G-protein activator.

Plant and Soil published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, COA of Formula: C16H10O5.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Islam, Tofazzal Md. published the artcileMicroscopic studies on attachment and differentiation of zoospores of the phytopathogenic fungus Aphanomyces cochlioides, Safety of 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, the publication is Journal of General Plant Pathology (2002), 68(2), 111-117, database is CAplus.

The mode of aggregation, attachment and differentiation of zoospores of the phytopathogenic fungus Aphanomyces cochlioides when interacting with the host and a host-specific attractant and a G-protein activator, mastoparan, was studied by light and SEM. When a zoospore approached very close to the host root, it seemed to halt, then coiled its anterior flagellum on its body. The halted zoospore appeared to contact the host surface with its posterior flagellum, which gradually drew the encysting zoospore onto the root surface. The spore then docked precisely on the root surface at its ventral face with the help of the posterior flagellum and anchored itself by releasing some adhesive materials. The adherent spore became a spherical after shedding its flagella and rapidly turned into an expanded cyst forming a smooth cyst coat around it, and finally changed into a smaller cystospore covered with a wrinkled surface. In contrast, the mastoparan- or cochliophilin A-stimulated zoospores on artificial membranes aggregated by using their posterior flagella before encystment. These contrasting phenomena suggest that A. cochlioides zoospores may use their posterior flagella for successful docking on the host surface or for aggregation of encysting spores in the absence of the host.

Journal of General Plant Pathology published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, Safety of 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wen, Yaolin published the artcilePhenolic constituents of Celosia cristata L. susceptible to spinach root rot pathogen Aphanomyces cochlioides, Related Products of dioxole, the publication is Bioscience, Biotechnology, and Biochemistry (2006), 70(10), 2567-2570, database is CAplus and MEDLINE.

Cochliophilin A (5-hydroxy-6,7-methylenedioxyflavone, 1), known as a host-specific attractant towards the zoospores of A. cochlioides, a cause of root rot and damping-off diseases of Chenopodiaceae, was found in the Amaranthaceae plant, Celosia cristata, that is susceptible to the pathogen. The content of 1 in Celosia seedlings was quantified as 1.4 μg/g fresh weight A new isoflavone, cristatein (5-hydroxy-6-hydroxymethyl-7,2′-dimethoxyisoflavone, 2), and five known flavonoids were also identified.

Bioscience, Biotechnology, and Biochemistry published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C9H7NO4, Related Products of dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Senda, Yasuhisa published the artcileCarbon-13 NMR spectra of methyl-1,3-dioxolanes, Application In Synthesis of 1193-11-9, the publication is Bulletin of the Chemical Society of Japan (1977), 50(10), 2813-14, database is CAplus.

The ¹³C NMR spectra of 13 Me substituted 1,3-dioxolanes were measured. The carbon chem. shifts of the Me groups imply that the 1,3-transannular nonbonded interaction of the Me groups is negligible, except in the cases of 2,2,4-trimethyl- and 2,2,4,5-tetramethyl-1,3-dioxolanes.

Bulletin of the Chemical Society of Japan published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C4H6N2, Application In Synthesis of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Tahara, S. published the artcileSimple flavones possessing complex biological activity, Name: 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, the publication is Studies in Natural Products Chemistry (2000), 457-505, database is CAplus.

A review with 87 references Two simple flavones, each of which exhibits distinct biol. activity despite their closely related structures, have been recognized by detailed bioassays, and bioassay-oriented isolation procedures. The identity of both flavones has been confirmed by synthesis. One of these compounds, 5-methoxy-6,7-methylenedioxyflavone has been found in an extract of Polygonum lapathifolium L. subsp. nodosum (Polygonaceae) using a screening test devised to detect antidotes against the benzimidazole fungicide, benomyl (or its active principle MBC, 1H-benzimidazol-2-ylcarbamic acid Me ester). The other compound, 5-hydroxy-6,7-methylenedioxyflavone, is a host-specific signalling substance that exudes from spinach roots and attracts zoospores of the phytopathogenic fungus Aphanomyces cochlioides the cause of spinach root rot. This review describes the bioassay, isolation and identification of these active compounds, and compares their activity with that of various other related, and unrelated, chems. of either plant or synthetic origin. The possible ecochem. role and mode of action of flavone and non-flavone antidotes and attractants is briefly discussed.

Studies in Natural Products Chemistry published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C8H8O3, Name: 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Msutu, Ath’enkosi published the artcileAcetals: a new organocatalysis chemotype for one-pot enantioselective α-amination, Name: 1,4-Dioxaspiro[4.5]decane, the publication is Tetrahedron Letters (2014), 55(14), 2295-2298, database is CAplus.

Conditions are described for one-pot Bronsted acid and organocatalyzed enantioselective α-amination of acetals and associated functionalities. Of the organocatalysts screened, proline tetrazole gave the highest ee, while aqueous monochloroacetic acid proved to be the best Bronsted acid activator regarding minimizing racemization and maximizing product yield. The reaction opens up the way for using masked carbonyl functionalities in organocatalysis.

Tetrahedron Letters published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Name: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Xu, Yu-lin published the artcileSynthesis of cyclohexanone ethylene ketal using H₃PW₁₂O₄₀/SiO₂ as catalyst, Formula: C8H14O2, the publication is Jingxi Huagong (2013), 30(6), 614-617, 655, database is CAplus.

A new environmental friendly catalyst, H₃PW₁₂O₄₀/SiO₂ was prepared by the sol-gel method, and characterized by means of FTIR and XRD. Cyclohexanone ethylene ketal was synthesized from cyclohexanone and ethylene glycol using H₃PW₁₂O₄₀/SiO₂ as catalyst. The influence factors on the yield of cyclohexanone ethylene ketal were also discussed. The optimum conditions were identified: molar ratio of cyclohexanone to ethylene glycol is 1:1.3, mass fraction of catalyst to reactants is 1.2%, cyclohexane dosage is 3 mL and reaction time is 45 min. The yield of cyclohexanone ethylene ketal can reach 89.7% under the optimum conditions.

Jingxi Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C13H10F2, Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wang, Wen-lan published the artcileSynthesis of vanillin propylene glycol acetal over different molecular sieve catalysts, COA of Formula: C11H14O4, the publication is Huaxue Gongchengshi (2009), 23(4), 1-3, database is CAplus.

The vanillin 1,2-propylene glycol acetal was synthesized using vanillin and 1,2-propylene glycol as starting materials and HZSM-5, HY, H beta, HMCM-22, HMCM-41 different type mol. sieve as the catalyst. The catalysts were characterized by means of N₂ adsorption-desorption and FT-IR of adsorption pyridine. The results indicate that the HMCM-22 mol. sieve has the higher activity and the each kind of mol. sieve active order is: HMCM-22 > H beta > USY > HY > HZSM-5 > HMCM-41. The higher activity was due to the large secondary pore structure of HMCM-22 mol. sieve and the suitable acidity.

Huaxue Gongchengshi published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C17H29BO2, COA of Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem