Day: November 21, 2022

Shen, Chuanlei published the artcileCondensation reaction of vanillin with 1,2-propanediol over silica supported cesium phosphotungstate catalysts, Name: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, the publication is Nanjing Gongye Daxue Xuebao, Ziran Kexueban (2010), 32(2), 22-25, 30, database is CAplus.

A series of cesium phosphotungstate catalysts supported on silica gel (SiO₂) were prepared and used to catalyze the condensation reaction of vanillin with 1,2-propanediol into vanillin propylene glycol acetal. The effects of substituted number of Cs⁺, loading of cesium phosphotungstate, catalyst amount, mole ratio of 1,2-propanediol to vanillin, and reaction time on the reactivity were investigated. Results showed that the catalyst with Cs⁺ substituted number of 2.5, and Cs salt loading of 40% exhibited the highest activity. Under optimal reaction conditions, i.e., reaction temperature 368 K, mole ratio of 1,2-propanediol to vanillin 2.4, catalyst mass fraction in reaction medium 1.5%, 30 mL benzene as water removal additive, and reaction time 3 h, the conversion of vanillin was 86.6% and the selectivity for vanillin propylene glycol acetal was 100%.

Nanjing Gongye Daxue Xuebao, Ziran Kexueban published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C7H16ClNO2, Name: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Tong, Shuo published the artcileCatalytic Enantioselective Double Carbopalladation/C-H Functionalization with Statistical Amplification of Product Enantiopurity: A Convertible Linker Approach, Computed Properties of 503538-69-0, the publication is Angewandte Chemie, International Edition (2017), 56(45), 14192-14196, database is CAplus and MEDLINE.

Combining a catalytic enantioselective reaction with dimerization in a single operation is an efficient way to upgrade the enantiomeric excesses (ee) of the product. Palladium-catalyzed reaction of N-(2-iodophenyl)-N-Me methacrylamide derivatives with oxadiazole afforded, by a double enantioselective carbopalladation/intermol. heteroarene C-H alkylation sequence, homodimers I (R¹ = H, 5-OMe, 5-Cl, 6-Cl, etc.; R² = Me, Bn, i-Pr, etc.) in good yields with excellent ee values. The dimer was subsequently elaborated to the monomer in which the linker (oxadiazole) was incorporated into the target product.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C3H5F3O, Computed Properties of 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Orlandi, Manuel published the artcileComputational Analysis of Enantioselective Pd-Catalyzed α-Arylation of Ketones, COA of Formula: C38H24F4O4P2, the publication is Journal of Organic Chemistry (2020), 85(17), 11511-11518, database is CAplus and MEDLINE.

The direct α-arylation of carbonyl compounds emerged over the last two decades as a straightforward method for the formation of C(sp³)-C(sp²) bonds. Mechanistic studies suggested a classical cross-coupling catalytic cycle. This consists of oxidative addition of the aryl halide (ArX) to the Pd(0)-catalyst, transmetalation of the Na- or K-enolate generated in situ, and subsequent reductive elimination. Even though the general reaction mechanism was thoroughly investigated, studies focusing on enantioselective variants of this transformation are rare. Here, the computational study of the [Pd(BINAP)]-catalyzed α-arylation of 2-methyltetralone with bromobenzene is reported. The whole reaction energy profile was computed and several mechanistic scenarios were investigated for the key steps of the reaction, which are the enolate transmetalation and the C-C bond-forming reductive elimination. Among the computed mechanisms, the reductive elimination from the C-bound enolate Pd complex was found to be the most favorable one, providing a good match with the stereoselectivity observed exptl. with different ligands and substrates. Detailed anal. of the stereodetermining transition structures allowed us to establish the origin of the reaction enantioselectivity.

Journal of Organic Chemistry published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, COA of Formula: C38H24F4O4P2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Xu, Zhaohui published the artcileSynthesis of 2-methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol (vanillin 1,2-propylene glycol acetal) in presence of ferric potassium sulfate [FeK(SO₄)₂], Recommanded Product: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, the publication is Shipin Keji (2006), 176-178, database is CAplus.

The title compound, vanillin 1,2-propylene glycol acetal was synthesized from vanillin and 1,2-propylene glycol using ferric potassium sulfate as catalyst. The factors influencing the synthesis were discussed and the better reaction conditions were as follows: vanillin 0.1 mol, molar ratio of vanillin/1,2-propylene glycol 1.0/2.4 (mol/mol), the amount of catalyst 2.0% in proportion to the total reactant materials, the amount of benzene 16 mL, and reaction time 3.0 h. The product yield reached 86.0%.

Shipin Keji published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C25H21N3O4, Recommanded Product: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Lu, Yueqing published the artcileSynthesis of novel carbon/silica composites based strong acid catalyst and its catalytic activities for acetalization, Related Products of dioxole, the publication is Bulletin of Materials Science (2012), 35(3), 419-424, database is CAplus.

Novel solid acid based on carbon/silica composites are synthesized through one-pot hydrothermal carbonization of hydroxyethylsulfonic acid, sucrose and tetra-Et orthosilicate (TEOS). The novel solid acid owned the acidity of 20 mmol/g, much higher than that of the traditional solid acids such as Nafion and Amberlyst-15 (08 mmol/g). The catalytic activities of the solid acid are investigated through acetalization. The results showed that the novel solid acid was very efficient for the reactions. The high acidity and catalytic activities made the novel carbon/silica composites based solid acid hold great potential for the green chem. processes.

Bulletin of Materials Science published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Related Products of dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Chen, Wen-long published the artcilePreparation and catalytic application of SO₄^2-/SnO₂-WO₃/KIT-6 complex solid acid, Application of 1,4-Dioxaspiro[4.5]decane, the publication is Guangzhou Huagong (2016), 44(7), 1-4, database is CAplus.

Complex solid acid of SO₄^2-/SnO₂-WO₃/KIT-6 was prepared through impregnation method using KIT-6 as template. The solid acid was used as catalyst for the Baeyer-Villiger oxidation of cyclic ketones and the condensation reaction between ketones/aldehyde and diols. It was found that the synthesized solid acid exhibited promising catalytic activity in the two kinds of reactions. The introducing of the WO₃ and KIT-6 increased not only the acidity but also the specific area of the solid acid, therefore, the catalytic activity of the solid acid was enhanced.

Guangzhou Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Application of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Tao, Duan-Jian published the artcileKinetics Study of the Ketalization Reaction of Cyclohexanone with Glycol Using Bronsted Acidic Ionic Liquids as Catalysts, Category: dioxole, the publication is Industrial & Engineering Chemistry Research (2012), 51(50), 16263-16269, database is CAplus.

It is remarkable that Bronsted acidic ionic liquids (BAILs) have several unique advantages in the acid-catalysis reaction, which avoids the tech. issues raised from mineral acids. The kinetics for the ketalization of cyclohexanone with glycol using BAILs as catalysts was therefore studied for the first time. The effects of various parameters such as kind of BAILs, temperature, catalyst loading, and molar ratio of the reactants on the conversion of cyclohexanone were examined in detail, and a pseudohomogeneous (PH) kinetic model was used successfully to correlate the exptl. data at from 313.15 to 343.15 K. The kinetic parameters such as reaction rate constant, activation energy, and chem. equilibrium constant then were proposed and utilized to interpret the catalytic activities of the BAILs catalysts. It was also validated from the comparison of catalytic performance among the BAILs, H₂SO₄, and solid resin that the BAILs were considered to be environmentally friendly and high efficient catalysts, and were suggested to replace mineral and solid acids in the synthesis of ketal.

Industrial & Engineering Chemistry Research published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H7NO4, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wu, Haijun published the artcilePromoting the conversion of poplar to bio-oil based on the synergistic effect of alkaline hydrogen peroxide, Safety of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Renewable Energy (2022), 107-117, database is CAplus.

The synergistic catalysis effect of NaOH and H₂O₂ on the hydrothermal liquefaction (HTL) of poplar was investigated and compared to the NaOH or H₂O₂ catalyzed HTL at different temperatures and 30 min residence time. GC-MS, GPC, FT-IR, HPLC and TGA were used to comprehensively characterize the phys. and chem. properties of liquefied products (bio-oil, lignin and solid residue). The results showed that the highest total bio-oil yield (70.65%) was obtained at 280°C with NaOH (35 g/L)/H₂O₂ (30 g/L) as catalysts. The average mol. weight and polydispersity index (PDI) were found to be lower compared to that from other conditions. As the NaOH concentration was increased, the bio-oil yield was improved. The concentration of H₂O₂ for the optimal synergistic effect was observed to be 30 g/L. GC-MS anal. showed that the bio-oil obtained by NaOH (35 g/L)/H₂O₂ (30 g/L) was characterized with the lowest N content. The synergistic effect promoted the higher production selectivity of o-xylene and p-xylene in the bio-oil.

Renewable Energy published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C11H22N2O4, Safety of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zhu, Haotian published the artcileSynthesis, crystal structure and catalytic activity of a Dawson-type tungstophosphate decorated by copper complexes, COA of Formula: C8H14O2, the publication is Yingyong Huaxue (2015), 32(4), 433-441, database is CAplus.

An inorganic-organic hybrid compound [Cu(H₂biim)₂(H₂O)][{Cu(H₂biim)₂}₂(P₂W₁₈O₆₂)]·11H₂O (H₂biim = 2,2′-biimidazole) (1) was hydrothermally constructed by the reaction of Cu(II)-H₂biim complexes and Dawson-type tungstophosphate, and characterized by single-crystal x-ray diffraction, IR spectroscopy (IR), X-ray powder diffraction (XRD), elemental anal. and electrochem. anal. Structural anal. showed that the polyanion [P₂W₁₈O₆₂]^6-, as a bidentate ligand, coordinates with two Cu²⁺ ions to form a bi-Cu(II)-supporting heteropolyanion [{Cu(H₂biim)₂}₂(P₂W₁₈O₆₂)]^2-, which was surrounded by an isolated [Cu(H₂biim)₂(H₂O)]²⁺ and eleven H₂O mols. The presence of N-H···O/OW hydrogen bonds between H₂biim mols. and polyoxoanion or water mols., in company with the synergistic effect of electrostatic interactions and π-π stack, gave a crystal material with 3-dimensional framework further. Compound 1 displayed good electrocatalytic activity toward the reduction of H₂O₂ and Na₂NO₂. Meanwhile it was also a good acid-catalyst for the synthesis of cyclohexanone ethylene ketal and could be recycled.

Yingyong Huaxue published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C17H14O5, COA of Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Lu, Baolan published the artcileCatalytic synthesis of cyclohexanone ethylene ketal over phosphotungstic acid/silica gel, Formula: C8H14O2, the publication is Jingxi Shiyou Huagong Jinzhan (2011), 12(12), 50-52, database is CAplus.

Cyclohexanone ethylene ketal I was synthesized with cyclohexanone and glycol as the materials, and the catalytic activity of phosphotungstic acid/silica gel catalyst in ketol reaction was studied. According to the results, phosphotungstic acid/silica gel (SG) is a good catalyst for the synthesis of cyclohexanone ethylene ketal. The optimum synthesis conditions were identified: n (cyclohexanone):n (glycol) = 1:1.4, amount of water-carrying agent (i.e. cyclohexane): 8 mL, reaction time: 30 min. The yield of cyclohexanone ethylene ketal can reach 76.4% at such conditions.

Jingxi Shiyou Huagong Jinzhan published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem