Month: November 2022

On January 1, 2014, Stoltz, Kristen L.; Alba, Andrea-Nekane R.; McDonald, Frank E.; Wieliczko, Marika B.; Bacsa, John published an article.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was Iodoetherification of Conformationally Restricted Dienyl Alcohols: Unexpected Formation of Oxocenes by 8-endo-Mode Oxacyclizations. And the article contained the following:

The synthesis of oxocenes I [R = H, (S)-Me, (R)-Me] via iodine-promoted 8-endo-mode oxacyclization from conformationally restricted dienyl alcs. was described. The unsaturated oxocane II was also prepared similarly. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to alkenyl alc preparation iodine oxacyclization, oxocene preparation diastereoselective regioselective, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Braga, Fernanda Gambogi; Coimbra, Elaine Soares; de Oliveira Matos, Magnum; Carmo, Arturene Maria Lino; Cancio, Marisa Damato; da Silva, Adilson David published an article in 2012, the title of the article was Synthesis and biological evaluation of some 6-substituted purines [Erratum to document cited in CA147:052743].Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole And the article contains the following content:

On page 530, the Abstract contained full citations instead of references numbers; the reference numbers are [11] and [12]. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to erratum purine alkylthio preparation antileishmanial, cytotoxicity leishmania alkylthiopurine derivative erratum, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On April 9, 2007, Gallos, John K.; Stathakis, Christos I.; Salapassidou, Maria J.; Grammatoglou, Constantinos E.; Koumbis, Alexandros E. published an article.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was A short alternative preparation of the bengazoles polyol side-chain segment. And the article contained the following:

A new short and efficient synthesis of the bengazoles side chain I is reported using a sequential diastereoselective Grignard addition, reduction, and regioselective hydroboration on a readily available D-ribose derivative The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to bengazole a synthon polyol isopropylidene hexane tetraol preparation, ribose diastereoselective grignard addition reduction regioselective hydroboration, Biomolecules and Their Synthetic Analogs: Others, Including Purines, Pyrimidine Nucleic Acid Bases, Flavins, Lignans and other aspects.Application In Synthesis of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On August 25, 2020, Zhang, Chen; Zhu, Guozhi; Lu, Yonghua; Gao, Qiu; Liao, Yuting; Li, Yao; Yan, Pangke published a patent.Application of 124038-36-4 The title of the patent was Preparation of 8-hydroxy-1H-quinolin-2-one bridge derivatives as muscarinic receptor M3 antagonists and beta 2-adrenergic receptor agonists. And the patent contained the following:

The invention discloses preparation method of 8-hydroxy-1H-quinolin-2-one bridge ring derivatives, which has the characteristics of diverse structure and high activity. For example, the invention compound I was prepared via multi-step reaction of 4-[[3-[[(7-tertbutoxycarbonyl-3-oxa-7-azabicyclo[3.3.1]nonane-9-yl)oxocarbonylamino]-Ph methyl] phenoxy] methyl] benzoic acid. The invention compounds can be used as muscarinic receptor M3 antagonists and beta 2-adrenergic receptor agonists. The experimental process involved the reaction of Methyl 3-(1,3-dioxolan-2-yl)benzoate(cas: 124038-36-4).Application of 124038-36-4

The Article related to preparation hydroxyquinolinone muscarinic receptor m3 antagonist adrenergic receptor agonist, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Application of 124038-36-4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On September 6, 2000, Hyldtoft, Lene; Madsen, Robert published an article.Recommanded Product: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was Carbohydrate carbocyclization by a novel zinc-mediated domino reaction and ring-closing olefin metathesis. And the article contained the following:

A general method for carbocyclization of carbohydrates is described using two consecutive organometallic transformations: a novel zinc-mediated domino reaction to give functionalized dienes followed by ring-closing olefin metathesis. In the first reaction, Me ω-deoxy-ω-iodo glycosides undergo reductive elimination with zinc to produce a terminal double bond. This also liberates the aldehyde which is immediately alkylated in situ by various organozinc reagents. The alkylation occurs under Barbier conditions with methylene iodide and several allyl bromides. Zinc plays a dual role by both promoting the reductive elimination and activating the alkyl halide. Vinylation is carried out by adding divinylzinc. When a new stereogenic center is generated, moderate to excellent stereocontrol is generally observed An amino group can be introduced by trapping the intermediate aldehyde as an imine prior to the alkylation. The reductive elimination-allylation sequence can also be promoted by indium metal. All the alkylations produce a second double bond, and the obtained dienes are subsequently subjected to ring-closing olefin metathesis to produce the corresponding carbocycles. A newly developed catalyst with an N-heterocyclic carbene ligand is more reactive toward these carbohydrate-derived dienes than com. available Grubbs catalyst. Acetylation of the free hydroxy groups improves the metathesis reaction significantly. Both five- and six-membered carbocycles are available by this route, including a number of conduritols and quercitols. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Recommanded Product: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to domino reaction cyclitol preparation cyclization, cyclitol preparation cyclization barbier reductive elimination, alditol diene catalyzed cyclization cyclitol preparation and other aspects.Recommanded Product: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On March 19, 2021, Kvasovs, Nikita; Iziumchenko, Valeriia; Palchykov, Vitalii; Gevorgyan, Vladimir published an article.Application of 38838-06-1 The title of the article was Visible Light-Induced Pd-Catalyzed Alkyl-Heck Reaction of Oximes. And the article contained the following:

A visible light-induced palladium-catalyzed oxidative C-H alkylation of oximes was developed. This mild protocol allowed for an efficient atom economical C-C bond construction of alkyl-substituted oximes. A broad range of primary, secondary and tertiary alkyl bromides and iodides, as well as a range of different formaldoximes, can efficiently underwent this transformation. The method featured visible light-induced generation of nucleophilic hybrid alkyl Pd radical intermediates, which upon radical addition at the imine moiety and a subsequent β-hydrogen elimination deliver substituted imines. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application of 38838-06-1

The Article related to oxime alkyl halide palladium catalyst diastereoselective alkylation heck reaction, alkyl oxime preparation, heck reaction, alkylation, light-induced, oxime, palladium, radical and other aspects.Application of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem