Tag: 100-200

Chemoenzymatic Synthesis of δ-Keto β-Hydroxy Esters as Useful Intermediates for Preparing Statins was written by Tartaggia, Stefano;Fogal, Stefano;Motterle, Riccardo;Ferrari, Clark;Pontini, Marta;Aureli, Roberto;De Lucchi, Ottorino. And the article was included in European Journal of Organic Chemistry in 2016.Category: dioxole The following contents are mentioned in the article:

Enantiopure (R)-3-hydroxy-5-oxohexanoic acid esters have proven to be useful intermediates in the synthesis of the side chain of statins, in view of the recently described preparation of rosuvastatin and other statins through aldol reactions. Herein, an improved synthesis of these intermediates, by combining chem. and enzymic reactions, is described. In particular, the selective reduction of a δ-ketal β-keto ester was identified as a key step to obtain derivatives with satisfactory optical purities for use in the synthesis of statins. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Category: dioxole).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of ketals of ethyl acetoacetate catalyzed by activated carbon supported SnCl₄·5H₂O under microwave irradiation was written by Zhang, Min;Yuan, Lin;Yuan, Xianyou. And the article was included in Guangzhou Huaxue in 2007.COA of Formula: C8H14O4 The following contents are mentioned in the article:

Two ketals were synthesized from Et acetoacetate with ethylene glycol and 1,2-propanediol using activated carbon supported SnCl₄·5H₂O (SnCl₄·5H₂O/C) as catalysts without solvent under microwave irradiation Under the optimum reaction conditions (SnCl₄·5H₂O/C (loaded amount 20%) 0.1 g), Et acetoacetate 5 mL, ethylene glycol 6 mL, microwave power 600 W, microwave irradiation time 2.5 mm, the yield of ketal was 81.6%. The products were characterized by IR. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1COA of Formula: C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.COA of Formula: C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of fructone by solid acid SO₄^2-/ZrO₂-TiO₂ was written by Liu, Xi-cheng. And the article was included in Guangzhou Huagong in 2011.SDS of cas: 6413-10-1 The following contents are mentioned in the article:

Fructone was synthesized with Et acetoacetate and glycol by using solid acid sulfate/zirconia-titania as catalyst. The effects of water-carrying reagent, feed ratio, reaction time, catalyst dosage on the yield of the product were studied. Results showed that the optimum reaction conditions were molar ratio of cyclohexanone to ethylene 1:1.5, catalyst dosage 2% of the total reactants, and the amount of cyclohexane 37.5% of the total reactants. After 2h reaction, the yield of fructone reached 76.8%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1SDS of cas: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.SDS of cas: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of fructone from ethyl acetoacetate and ethylene glycol in the presence of copper benzenesulfonate as catalyst was written by Dong, Jing-hua. And the article was included in Huagong Jishu Yu Kaifa in 2013.Related Products of 6413-10-1 The following contents are mentioned in the article:

Fructone was prepared by condensation reaction of Et acetoacetate and ethylene glycol in the presence of copper benzene sulfonate. The influences of the reaction conditions on the yield of fructone were investigated. The optimum reaction conditions were as follows: molar ratio of Et acetoacetate/ethylene glycol, 1:1.5; catalyst dosage, 1.5wt% of reactants; water-carrying agent, cyclohexane; reaction time, 60min. Under the optimum reaction conditions, the yield of fructone was up to 82.7%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Related Products of 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Related Products of 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Polysubstituted Oxygen Heterocycles by a Reformatsky-Type Reaction/Reductive Cyclization Approach from Enantiopure β-Ketosulfoxides was written by Colobert, Francoise;Choppin, Sabine;Ferreiro-Mederos, Leticia;Obringer, Michel;Luengo Arratta, Sandra;Urbano, Antonio;Carreno, M. Carmen. And the article was included in Organic Letters in 2007.HPLC of Formula: 6413-10-1 The following contents are mentioned in the article:

The stereoselective synthesis of tetrasubstituted tetrahydrofurans and trisubstituted tetrahydropyrans bearing a sulfoxide moiety was achieved by reductive cyclization (Et₃SiH/TMSOTf) of the corresponding enantiopure hydroxy ketones protected as dioxolanes. The latter are easily accessible from a Reformatsky-type reaction between α-bromo-α’-sulfinyl ketones and protected α- or β-ketoaldehydes, followed by diastereoselective reduction of the resulting β-ketosulfoxide. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1HPLC of Formula: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.HPLC of Formula: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Highly efficient heterogeneous procedure for the synthesis of fructone fragrancy was written by Gao, Shan;Liang, Xue Zheng;Yang, Jian Guo;He, Ming Yuan. And the article was included in Science in China, Series B: Chemistry in 2008.Category: dioxole The following contents are mentioned in the article:

A novel heterogeneous strong acid catalyst was synthesized through the copolymerization of p-toluenesulfonic acid and paraformaldehyde and utilized for the synthesis of fructone. The results showed that the catalyst was very efficient for the reaction with the yield over 95%. The advantages of extremely high d. of acidity, high thermal and chem. stability, low cost for the simple synthetic procedure, and reusability made the catalyst one of the best choices for the reaction. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Category: dioxole).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Efficient and straightforward preparation of a building block for (-)-teubrevin G synthesis via chemically diverse oriented synthesis was written by Velazquez, Daniel Garcia;Luque, Rafael. And the article was included in Tetrahedron Letters in 2011.Reference of 6413-10-1 The following contents are mentioned in the article:

A rapid and efficient methodol. to highly functionalized mol. units well suited as scaffolds for diversity-oriented mol. construction in the synthesis of natural products was reported. A key macrocyclic intermediate I in the synthesis of the neo-clerodane diterpene (-)-teubrevin G was successfully synthesized in a 5-step sequence in a 70% overall yield using a novel intramol. coupling between an allylborating agent and a 1,5-dialdehyde moiety. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Reference of 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Reference of 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of new efficient laser dyes of red spectral range, the DCM analogs, based on 2-aryl-6-methyl-4H-pyrone was written by Ponomareva, O. V.;Lugovskii, A. P.;Lugovskii, A. A.;Males, M. P.;Komlev, I. V.;Nifant’ev, E. E.. And the article was included in Russian Journal of General Chemistry in 2011.Recommanded Product: Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:

A new method was developed for the synthesis of 2-aryl-6-methyl-4H-pyrones by the condensation of arylmethylketones with the acetoacetic ester ethylene ketal in the presence of sodium alkoxylate. New laser merocyanine dyes, the analogs of 4-dicyanomethylene-2-methyl-6-[(4-dimethylamino)styryl]-4H-pyran (DCM), were obtained based on the synthesized 2-aryl-4-pyrones. The dyes are characterized by high generation efficiency in the red spectral range. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Recommanded Product: Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of fructone using copper methanesulfonate as catalyst was written by Peng, Anshun;Chen, Changxing. And the article was included in Riyong Huaxue Gongye in 2005.Category: dioxole The following contents are mentioned in the article:

Fructone (i.e., 2-methyl-1,3-dioxolane-2-acetic acid Et ester) was synthesized using Et acetoacetate and glycol as starting materials and copper methanesulfonate as catalyst. Factors influencing the yield were examined by the orthogonal experiments The optimum conditions were as follows: n(Et acetoacetate)/n(glycol) 1:1.5, catalyst dosage 7.5 g, water carrying agent 7.5 mL, reaction under reflux condition for 3 h. The yield can achieve 88.2%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Category: dioxole).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Highly efficient procedure for the synthesis of fructone fragrance using a novel carbon based acid was written by Hu, Baowei;Li, Chunqing;Zhao, Sheng-Xian;Rong, Lin-Mei;Lv, Shao-Qin;Liang, Xuezheng;Qi, Chenze. And the article was included in Molecules in 2010.Recommanded Product: 6413-10-1 The following contents are mentioned in the article:

A highly efficient synthesis of fructone in yields over 95% has been developed using the novel carbon based acid, obtained via one-step hydrothermal carbonization of furaldehyde and hydroxyethylsulfonic acid, as catalyst. The advantages of the catalyst are high activity, stability, reusability, low cost and simplicity of synthesis, and applicability to the reactions of various diols with β-keto esters. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Recommanded Product: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Recommanded Product: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem