Month: November 2022

On December 24, 1999, Gallos, John K.; Koumbis, Alexandros E.; Xiraphaki, Vassiliki P.; Dellios, Constantinos C.; Coutouli-Argyropoulou, Evdoxia published an article.COA of Formula: C9H15IO4 The title of the article was Diastereocontrol in the intramolecular cycloadditions of 2-substituted-erythro-3,4-isopropylidenedioxyhex-5-enenitrile oxides. And the article contained the following:

The influence of the 2-substituent on the diastereoselectivity of the intramol. cycloadditions in a series of 2-substituted-erythro-3,4-isopropylidenedioxyhex-5-enenitrile oxides, generated in situ from selected sugar derivatives, was examined in synthesis of aminocyclopentitols, e.g. I. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).COA of Formula: C9H15IO4

The Article related to stereoselective intramol cycloaddition erythrodioxyhexenenitrile synthesis aminocyclopentitol, Carbohydrates: Amines and other aspects.COA of Formula: C9H15IO4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On March 21, 1994, Gallos, John K.; Goga, Efthymia G.; Koumbis, Alexandros E. published an article.Formula: C9H15IO4 The title of the article was Expeditious synthesis of aminocyclopentitols from D-ribose via intramolecular nitrone cycloaddition. And the article contained the following:

The synthesis of aminocyclopentitol I (a key-intermediate in the preparation of carbocyclic nucleosides) and its N-substituted derivatives, has been achieved by the intramol. nitrone cycloadditions of a γ-unsaturated aldehyde, easily accessible from D-ribose, followed by reductive N-O bond cleavage in the resulting bicyclic oxazanes II. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Formula: C9H15IO4

The Article related to ribose conversion aminocyclopentitol, aminocyclopentitol, bicyclic oxazane preparation reductive bond cleavage, Carbohydrates: Amines and other aspects.Formula: C9H15IO4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On December 23, 1988, Classon, Bjoern; Liu, Zhengchun; Samuelsson, Bertil published an article.SDS of cas: 38838-06-1 The title of the article was New halogenation reagent systems useful for the mild one-step conversion of alcohols into iodides or bromides. And the article contained the following:

Three new iodination and bromination reagent systems based upon phosphines are described, in which the phosphorus containing products are readily removed from the organic phase of the reaction mixture Reactions were carried out on suitably protected carbohydrates. The halogenation reagent systems consist of iodine (or bromine), imidazole and one of the following reagents: (A); Ph2PCl, (B); (p-dimethylaminophenyl)diphenylphosphine or (C); polymer-bound triphenylphosphine. The solvent used is toluene, and the phosphorous containing products are removed from the toluene phase by extraction into an aqueous sodium carbonate or sodium hydroxide phase (A); by extraction into an aqueous hydrochloric acid (pH≈1) phase (B); and by filtration (C). Ph2PCl is com. available and halogenation reagent system (A) represents the most reactive (shorter reaction time and lower temperature), of the three systems. Yields for all systems are high. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).SDS of cas: 38838-06-1

The Article related to halogenation carbohydrate reagent system, bromination carbohydrate reagent system, iodination carbohydrate reagent system, Carbohydrates: General and other aspects.SDS of cas: 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On June 30, 2007, Shitikova, O. V.; Ivanova, N. A.; Valiullina, Z. R.; Miftakhov, M. S.; Spirikhin, L. V. published an article.Safety of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole The title of the article was 1H NMR study on intramolecular hydrogen bonding in 2,3-O-isopropylidene-D-ribofuranosides and their 5(4)-hydroxy derivatives. And the article contained the following:

A 1H NMR study showed the possibility for intramol. hydrogen bonding in 5(4)-hydroxy derivatives of 2,3-O-isopropylidene-β-D-ribofuranose in CDCl3. The obtained data were used to interpret differences in the 1H NMR spectra of structurally related 5-halo-2,3-O-isopropylidene-D-ribofuranosides and four diastereoisomeric 5-bromo-5-deoxy-4-hydroxy-2,3-O-isopropylidene-D-ribofuranosides. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Safety of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to nmr hydrogen bond ribofuranoside, Carbohydrates: Glycosides and other aspects.Safety of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On May 21, 2008, Zhu, Renfa published a patent.Product Details of 38838-06-1 The title of the patent was Method for synthesizing 1,2,3-O-triacetyl-5-deoxy-D-ribofuranose. And the patent contained the following:

The title method comprises adopting D-ribose as raw material, performing glycosidation and esterification to obtain 2,3-O-isopropylidene-5-O-p-toluenesulfonyl-D-ribofuranose, performing iodination with sodium iodide or potassium iodide to obtain 2,3-O-isopropylidene-5-iodo-5-deoxy-D-ribofuranose, performing catalytic hydrogenation to obtain 2,3-O-isopropylidene-5-deoxy-D-ribofuranose, and hydrolyzing to obtain the final product with m.p. of 62-64°C. The method has the advantages of mild reaction condition, wide raw material resources, no pollution, and high yield (37.8%). The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Product Details of 38838-06-1

The Article related to deoxyribofuranose triacetate preparation green chem, Carbohydrates: Glycosides and other aspects.Product Details of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Soengas, Raquel G.; Silva, Artur M. S. published an article in 2013, the title of the article was Domino Reaction of Iodoglycosides: Synthesis of Carbohydrate-Based Nitroalkenes.Electric Literature of 38838-06-1 And the article contains the following content:

Herein we describe a tandem fragmentation/H reaction of iodoglycosides, which involves formation of a carbon-carbon double bond and a carbon-carbon single bond. If the fragmentation of Me 5-iodo-ribofuranoside is mediated by zinc/catalytic indium in the presence of bromonitromethane, a separable mixture of a 1-nitro-5-hexene and a 1-bromo-1-nitro-5-hexene is obtained in moderate yields with good diastereoselectivities. However, if the reaction is mediated by nBuLi in the presence of nitromethane, the corresponding 1-nitro-5-hexene is obtained as the only product in excellent yield and stereoselectivity in a one-pot synthetic protocol. This is a general methodol. that can be applied to iodopyranoses and iodofuranoses with different protecting groups for the efficient preparation of highly functionalized 1-nitro-5-hexenes or 1-nitro-6-heptenes. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Electric Literature of 38838-06-1

The Article related to carbohydrate nitroalkene preparation fragmentation henry iodoglycoside, Carbohydrates: Glycosides and other aspects.Electric Literature of 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On November 5, 1993, Blanchard, Pierre; Da Silva, Adilson D.; El Kortbi, Mohammed S.; Fourrey, Jean Louis; Robert-Gero, Malka published an article.Formula: C9H15IO4 The title of the article was Zinc-iron couple induced conjugate addition of alkyl halide derived radicals to activated olefins. And the article contained the following:

Addition of halo glycosides, e.g. I (R = iodo), with olefins, e.g. CH2:CHCO2Me, in the presence of Zn-Fe gave the corresponding glycosides, e.g. I (R = CH2CH2CO2Me),. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Formula: C9H15IO4

The Article related to haloalkane addition glycoside zinc iron catalyst, homolytic addition halo glycoside olefin, Carbohydrates: Glycosides and other aspects.Formula: C9H15IO4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On March 31, 1998, Oshikawa, Tatsuo; Yamashita, Mitsuji; Seo, Kuniaki; Hamauzu, Yoshihiro published an article.Recommanded Product: 38838-06-1 The title of the article was X-ray single crystal structure analyses of 5-deoxy-5-C-(alkylphosphinyl)-glucopyranose. And the article contained the following:

X-ray crystallog. analyses were performed on single crystals of 1,2,3,4-tetra-O-acetyl-5-deoxy-5-C-(isopropylphosphinyl)-D-ribopyranoses, 1,2,3,4-tetra-O-acetyl-5-deoxy-5-C-(isopropylphosphinyl)-D-xylopyranoses, and 1,2,4-tri-O-acetyl-5-deoxy-3-O-methyl-5-C-(phenylphosphinyl)-D-ribopyranoses. These compounds have the (RP) configuration at the phosphorus atom with the 4C1 conformation of the pyranose ring, and the conformation supported by NMR studies. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Recommanded Product: 38838-06-1

The Article related to mol structure deoxyalkylphosphinylglucopyranose, crystal structure deoxyalkylphosphinylglucopyranose, Carbohydrates: Glycosides and other aspects.Recommanded Product: 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Hanessian, S.; Lavallee, P. published an article in 1976, the title of the article was Direct replacement of primary hydroxyl groups by halogen.Name: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole And the article contains the following content:

Approx. 1:1 Ph3P and N-halosuccinimide (halo = Br, Cl, iodo) in DMF gave selective halogenation of primary OH groups in polyols. Thus, addition of Ph3P to Me 2,3-O-isopropylidene-β-D-ribofuranoside and N-iodosuccinimide in DMF yielded 71% Me 5-deoxy-5-iodo-2,3-O-isopropylidene-β-D-ribofuranoside. Similarly prepared were Me 2,3,4-tri-O-acetyl-6-bromo-6-deoxy-α-D-glucopyranoside, 5′-bromo-5′-deoxy-2′,3′-O-isopropylideneuridine, and 6-bromo-6-deoxy-α,α-trehalose heptoacetate. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Name: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

The Article related to hydroxyl group halogenation selective, glycoside selective halogenation, nucleoside selective halogenation, Carbohydrates: Glycosides and other aspects.Name: (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

On August 31, 1994, Mootoo, David; Wilson, Phyllis; Jammalamadaka, Vasu published an article.Recommanded Product: 38838-06-1 The title of the article was Application of the Keck radical coupling reaction to the preparation of allylated C5 furanosides and C6 pyranosides. And the article contained the following:

Allylated C5 furanosides, e.g. I, and C6 pyranosides, e.g. II, were prepared from known monosaccharide diol or polyol derivatives via a reaction sequence involving the initial selective formation of the primary iodide followed by application of the Keck allyl radical coupling reaction. Although the yields of the products in the coupling reaction were somewhat modest (usually 55-65%), the protocol was applicable to a variety of substrates, including sterically crowded cases, is exptl. simple and suitable for large scale preparations The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Recommanded Product: 38838-06-1

The Article related to monosaccharide keck homolytic coupling, keck allylation iodination monosaccharide, glycoside pyranoside furanoside, Carbohydrates: Glycosides and other aspects.Recommanded Product: 38838-06-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem