Wang, Jun-Fei published the artcileSynthesis of Ring A-Modified Baicalein Derivatives, Application of 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, the publication is Helvetica Chimica Acta (2011), 94(12), 2221-2230, database is CAplus.
Baicalein (5,6,7-trihydroxyflavone), an important active constituent of the traditional Chinese herb Scutellaria baicalensis, exhibited antitumor activity and inhibitory activity against P-gp 170. The syntheses of 25 baicalein derivatives are described here. These compounds were systematically modified with O-alkylation and O-acylation at HO-C(5), HO-C(6), and HO-C(7), singly or in combination, on the ring A of baicalein in order to evaluate the effects of such modifications on their inhibitory activities against multidrug-resistant tumor cell lines and P-gp 170 (no data). Highly selective and efficient alkylations at HO-C(7) of peracetylated baicalein were the key to the distinction between HO-C(6) and HO-C(7) of baicalein.
Helvetica Chimica Acta published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C13H11NO, Application of 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem