Dioxole related

Zhong, Shaofeng published the artcilePhosphorus promoted SO₄^2-/TiO₂ solid acid catalyst for acetalization reaction, Synthetic Route of 177-10-6, the publication is Journal of the Chilean Chemical Society (2015), 60(3), 3005-3008, database is CAplus.

A novel phosphorus modified SO₄^2-/TiO₂ catalyst was synthesized by a facile coprecipitation method, followed by calcination. The catalytic performance of this novel solid acid was evaluated by acetalization. The results showed that the phosphorus was very efficient to enhance the catalytic activity of SO₄^2-/TiO₂. The solid acid owned high activity for the acetalization with the yields over 90%. Moreover, the solid acid could be reused for six times without loss of initial catalytic activities.

Journal of the Chilean Chemical Society published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C3H3Br2ClO, Synthetic Route of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Barbosa, Sandro L. published the artcileKetalization of ketones to 1,3-dioxolanes and concurring self-aldolization catalyzed by an amorphous, hydrophilic SiO₂-SO₃H catalyst under microwave irradiation, HPLC of Formula: 177-10-6, the publication is Journal of the Brazilian Chemical Society (2018), 29(8), 1663-1671, database is CAplus.

The amorphous, mesoporous SiO₂-SO₃H catalyst with a surface area of 115 m² g^-1 and 1.32 mmol H⁺ per g was very efficient for the protonation of ketones on a 10% (m/m) basis, and the catalyst-bound intermediates could be trapped by polyalcs. to produce ketals in high yields or suffer aldol condensations within minutes under low-power microwave irradiation The same catalyst could easily reverse the ketalization reaction.

Journal of the Brazilian Chemical Society published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, HPLC of Formula: 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Tahara, Satoshi published the artcileThe third naturally occurring attractant toward zoospores of phytopathogenic Aphanomyces cochlioides from the Spinacia oleracea host plant, Related Products of dioxole, the publication is Bioscience, Biotechnology, and Biochemistry (2001), 65(8), 1755-1760, database is CAplus and MEDLINE.

A bioassay-guided survey of spinach leaf constituents resulted in 5,4′-dihydroxy-3,3′-dimethoxy-6,7-methylenedioxyflavone (I) being identified as the third naturally-occurring attractant in the host plant toward the zoospores of its pathogen, Aphanomyces cochlioides. The isolate showed attracting activity around Chromosorb W AW particles (60-80 mesh) coated with a 10^-5 M solution in a zoospore suspension. However, this activity was 1/100-1/1000 less than that of cochliophilin A, an attractant in the roots of spinach. Bioassays with the present isolate and related compounds revealed that 5,3′,4′-trihydroxy-3-methoxy-6,7-methylenedioxyflavone did not possess attractant activity, but rather weak antagonistic activity toward the former two attractants from spinach.

Bioscience, Biotechnology, and Biochemistry published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C12H14IN, Related Products of dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Pihlaja, Kalevi published the artcileCarbon-13 nuclear magnetic resonance studies on saturated heterocycles. Part I. Substituent effects on the carbon-13 chemical shifts of methyl-substituted 1,3-dioxolanes, Formula: C6H12O2, the publication is Finnish Chemical Letters (1977), 141-3, database is CAplus.

The 13C chem. shifts for 1,3-dioxolane and eleven Me-substituted derivatives are reported. The magnitude of the substituent effects, compared with those for cyclopentane and 1,3-dioxane, indicate that the 1,3-dioxolane ring is a dynamic mixture of conformations and that only 2,2-di-Me substitution shows increased steric demands.

Finnish Chemical Letters published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Courtney, Timothy D. published the artcileLiquid-phase dehydration of propylene glycol using solid-acid catalysts, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Applied Catalysis, A: General (2012), 59-68, database is CAplus.

In this work we combine experiments with D. Functional Theory (DFT) calculations to investigate the heterogeneous dehydration of propylene glycol. The reactions were carried out with pure, liquid propylene glycol over MFI-framework zeolite catalysts or the mesoporous sulfonic-acid resin Amberlyst 36Dry. When Amberlyst 36Dry was used, propylene glycol dehydrated to form propionaldehyde with 77% selectivity. All of the propionaldehyde further reacted with propylene glycol to form a cyclic acetal. The final products consisted of 78% acetal, 13% dipropylene glycol, and the remaining 9% was composed of acetone and a cyclic ketal formed from acetone. The zeolite catalysts demonstrated significantly higher selectivity toward dipropylene glycol compared to Amberlyst 36Dry. Furthermore, the zeolite had a lower conversion to cyclic acetals, improving the selectivity toward C3 products, acetone and propionaldehyde. DFT calculations confirmed that propionaldehyde is the favorable product in both catalysts, since it can be formed either through dehydration of the secondary hydroxyl group or via dehydration of the primary hydroxyl group with a concerted pinacol rearrangement. However, in the case of zeolites, the cyclic acetals experience steric hindrance since their size is comparable to that of the zeolite pores. Thus we argue that the cyclic acetals produced over the zeolite catalyst were formed homogeneously from the C3 products which diffused out of the zeolite pores.

Applied Catalysis, A: General published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Samoilov, Vadim O. published the artcileThe Joint Synthesis of 1,2-Propylene Glycol and Isopropyl Alcohol by the Copper-Catalyzed Hydrogenolysis of Solketal, Name: 2,2,4-Trimethyl-1,3-dioxolane, the publication is ACS Sustainable Chemistry & Engineering (2019), 7(10), 9330-9341, database is CAplus.

A synthetic strategy from glycerol to 1,2-propylene glycol (1,2-PG) via heterogeneously catalyzed hydrogenolysis of solketal (2,2-dimethyl-4-(hydroxymethyl)-1,3-dioxolane) has been proposed for the first time. Upon the hydrogenolysis over 60 wt % Cu/Al₂O₃ at 200-240 °C, solketal has been converted into mixtures of isopropanol and 1,2-PG with high yield (up to 94 mol %). Under similar conditions, the catalyst specific productivity (a yield of 1,2-PG per unit of mass of the catalyst) was about 2.65 times higher, when solketal was the reaction feed instead of glycerol. The reaction was also performed under atm. pressure in the vapor phase, where the solketal hydrogenolysis gave 93 mol % selectivity to 1,2-PG with a conversion of 24%. A plausible reaction mechanism for the solketal hydrogenolysis has been proposed.

ACS Sustainable Chemistry & Engineering published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Name: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Samoilov, Vadim published the artcileBio-based solvents and gasoline components from renewable 2,3-butanediol and 1,2-propanediol: synthesis and characterization, Safety of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Molecules (2020), 25(7), 1723, database is CAplus and MEDLINE.

In this study approaches for chem. conversions of the renewable compounds 1,2- propanediol (1,2-PD) and 2,3-butanediol (2,3-BD) that yield the corresponding cyclic ketals and glycol ethers have been investigated exptl. Cyclic ketals have been obtained by the direct reaction of the diols with lower aliphatic ketones (1,2-PD + acetone → 2,2,4-trimethyl1,3-dioxolane (TMD) and 2,3-BD + butanone-2 → 2-ethyl-2,4,5-trimethyl-1,3-dioxolane (ETMD)), for which the ΔH⁰r, ΔS⁰r and ΔG⁰r values have been estimated exptl. The monoethers of diols could be obtained through either hydrogenolysis of the pure ketals or from the ketone and the diol via reductive alkylation. In the both reactions, the cyclic ketals (TMD and ETMD) have been hydrogenated in nearly quant. yields to the corresponding isopropoxypropanols (IPP) and 3- sec-butoxy-2-butanol (SBB) under mild conditions (T = 120-140°C, p(H2) = 40 bar) with high selectivity (>93%). Four products (TMD, ETMD, IPP and SBB) have been characterized as far as their phys. properties are concerned (d., melting/b.ps., viscosity, calorific value, evaporation rate, Antoine equation coefficients), as well as their solvent ones (Kamlet-Taft solvatochromic parameters, miscibility, and polymer solubilization). In the investigation of gasoline blending properties, TMD, ETMD, IPP and SBB have shown remarkable antiknock performance with blending antiknock indexes of 95.2, 92.7, 99.2 and 99.7 points, resp.

Molecules published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Safety of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Quivoron, Claude published the artcileSecondary structure of polysaccharides. I. Proton acceptor character of oxygen atoms present in an acetal function by ir spectroscopy, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Journal de Chimie Physique (1966), 63(9), 1199-209, database is CAplus.

In CCl4 solution, o-cresol gives H bond complexes with ethers, acetals, ether-acetals, and diacetals. Thermodynamic values K1, ΔG0, ΔH0, and ΔS0, characterizing these complexes were determined by ir spectroscopy. In the case of mols, containing several proton acceptor sites, it is possible to estimate intrinsic association constants which relate the participation of every heteroatom to the 1:1 complex equilibrium The acetal O atoms are probably the best proton acceptor sites contained in a polyglucosidic structure.

Journal de Chimie Physique published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Quivoron, Claude published the artcileInvestigation, by infrared spectroscopy, of the proton-acceptor character of certain ethers and acetals, Name: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Compt. Rend. (1964), 259(11), 1845-7, database is CAplus.

For iso-Pr₂O, THF, tetrahydropyran, and dioxane, the proton acceptor character has been determined by measuring the intensity of the O-H band of the unassocd. ο-cresol (diluted in CCl₄) vs. that of the H-bonded compound after the proton acceptor was added. (A) For the monoethers, the stability is higher for cyclic than for iso-Pr complexes, (B) THF is a stronger acceptor than tetrahydropyran at room temperature, the trend being reversed at -10°, and (C) the accumulation of 2 acceptor sites in dioxane causes a decreasing of the intrinsic basicity of each, the effect being emphasized if 2 O are bonded to the same C as in cyclic formals. The presence of electrorepulsive groups has a partial opposite effect.

Compt. Rend. published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Name: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Ishida, Naoki published the artcileConstruction of indole skeletons by sequential actions of sunlight and rhodium on α-aminoacetophenones, Computed Properties of 503538-69-0, the publication is Chemistry Letters (2013), 42(9), 1076-1078, database is CAplus.

Indole skeletons were constructed from 2-(N-aryl-N-methylamino)acetophenone derivatives and a sequential action of solar radiation (sunlight) and a rhodium catalyst [bis[(1,2,5,6-η)-1,5-cyclooctadiene]di-μ-(hydroxy)dirhodium]. This method presents an example of the direct use of sunlight in organic synthesis. The synthesis of the target compounds was achieved using 2-(methylphenylamino)-1-(phenyl)ethanone (I) and related substances as starting materials. The target compounds thus formed included 1-methyl-3-phenyl-1H-indole (II) and related compounds 1,1′-[(4R)-2,2,2′,2′-Tetrafluoro[4,4′-bi-1,3-benzodioxole]-5,5′-diyl]bis[1,1-diphenylphosphine] [(R)-difluorphos] was used for an enantioselective synthesis variant toward the formation of chiral 2,3-dihydro-1-methyl-3-phenyl-1H-indol-3-ol and chiral 2,3-dihydro-3-hydroxy-1-methyl-3-phenyl-1H-indole-5-carboxylic acid Me ester.

Chemistry Letters published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Computed Properties of 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem