Dioxole related

Cheng, Shengxian published the artcileCrystallinity after decarboxylation of a metal-carboxylate framework: indestructible porosity for catalysis, Safety of 1,4-Dioxaspiro[4.5]decane, the publication is Dalton Transactions (2020), 49(34), 11902-11910, database is CAplus and MEDLINE.

We report a curious case study of a Zr(IV)-carboxylate framework, which retains significant crystalline order after cascade thermocyclization of its linker components, and – more notably – after the crucial carboxylate links were severed by heat. Vigorous heat treatment (e.g., 450°C and above) benzannulates the multiple alkyne groups on the linker to generate linked nanographene blocks and to afford real stability. The resultant Zr oxide/nanographene hybrid solid is stable in saturated NaOH and concentrated H₃PO₄, allowing a convenient anchoring of H₃PO₄ into its porous matrix to enable size-selective heterogeneous acid catalysis. The Zr oxide components can also be removed by strong hydrofluoric acid to further enhance the surface area (up to 650 m² g^-1), without collapsing the nanographene scaffold. The crystallinity order and the extensive thermal transformations were characterized by X-ray diffraction, scanning transmission electron microscopy (STEM), IR, solid state NMR and other instrumental methods.

Dalton Transactions published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Safety of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Peng, Anshun published the artcileSynthesis of vanillin propylene glycol acetal using calcium methanesulfonate as catalyst, Application In Synthesis of 68527-74-2, the publication is Huaxue Shijie (2005), 46(12), 752-753, database is CAplus.

Vanillin propylene acetal was synthesized using vanillin and propylene glycol as starting materials and Ca methanesulfonate as catalyst. Factors influencing the yield were examined The optimum conditions were as follows: vanillin: 1,2-propanediol : catalyst : dehydration agent 0.15 mol : 0.225 mol : 1.00 g : 15 mL and refluxing for 3.0 h. The yield was above 87.5% under optimum conditions.

Huaxue Shijie published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Application In Synthesis of 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Schnurpfeil, D. published the artcileLiquid-phase oxidation of 1,3-dioxolanes, Quality Control of 1193-11-9, the publication is Journal fuer Praktische Chemie/Chemiker-Zeitung (1994), 336(2), 155-9, database is CAplus.

The oxidation rate and the kind of oxidation products in the oxidation reactions of the 1,3-dioxolanes with mol. oxygen in liquid phase were investigated. The 2-methyl-substituted 1,3-dioxolane has a lower, the 4-methyl-substituted 1,3-dioxolane has a higher oxidation rate than the non-substituted 1,3-dioxolane. The 2,2-disubstituted 1,3-dioxolanes show no oxidation but a hydrolytic reaction. The main-products of the liquid-phase oxidation of the 1,3-dioxolanes are the glycolcarbonic acid monoesters and the 2-oxo-1,3-dioxolanes. Their formation is proved by gas chromatog., GC/MS-coupling, DC and ¹³C-NMR-spectroscopy.

Journal fuer Praktische Chemie/Chemiker-Zeitung published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Quality Control of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Gelas, Jacques published the artcileStudies of cyclic acetals. XXV. Sulfur-containing heterobicycles derived from α-thioglycerol. Synthesis of alkyl-2,8-dioxa-6-thiabicyclo[3.2.1]octanes, Quality Control of 1193-11-9, the publication is Canadian Journal of Chemistry (1983), 61(7), 1487-93, database is CAplus.

I (R, R¹, R² = H, H, H; Me, H, H; Me, H, Me; Me, Me, H; Ph, H, H; H, H, Me; H, H, Ph) and II were prepared by one or more of four methods studied, e.g., cyclization of HOCH₂C(OH)R¹CH₂Cl with RCOCHR²Cl to give III, followed by cyclization with Na₂S.

Canadian Journal of Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Quality Control of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Chen, Hanping published the artcileThe new insight about mechanism of the influence of K₂CO₃ on cellulose pyrolysis, Safety of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Fuel (2021), 120617, database is CAplus.

Potassium salt is a nonnegligible inorganic element in biomass, and it has a significant impact on the thermal behavior of biomass. To understand the mechanism of potassium on cellulose pyrolysis in depth, the evolution of functional groups of char combined with the characteristics of volatiles from cellulose pyrolysis with K₂CO₃ between 150 and 600°C was investigated using two-dimensional perturbation correlation IR spectroscopy (2D-PCIS). It was found that the addition of K₂CO₃ changed the decomposition pathway of cellulose, and reduce the initial temperature of cellulose decomposition from 250°C to 150°C. And K₂CO₃ accelerated the deconstruction of hydrogen bonding, and rupture of C5-O, C-C, glycosidic bond of cellulose crystal structure to form light mol. liner aliphatic compounds and CO, CO₂ at lower temperature (150-250°C). At higher temperature (>250°C), it accelerated the generation of phenol C-O of pyrolysis char and inhibited the generation of aliphatic ether.

Fuel published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Safety of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

He, Zhi-Tao published the artcileEfficient access to bicyclo[4.3.0]nonanes: copper-catalyzed asymmetric silylative cyclization of cyclohexadienone-tethered allenes, Formula: C38H24F4O4P2, the publication is Angewandte Chemie, International Edition (2015), 54(49), 14815-14818, database is CAplus and MEDLINE.

The creation of three consecutive chiral carbon centers in one step is achieved using Cu-catalyzed asym. silylative cyclization of cyclohexadienone-tethered allenes I (1a–x), in reaction with PhMe₂SiBpin (2), catalyzed by CuCl/L or CuCl/L₂ (L = BINOL phosphoramidite; L₂ = BIPHEP, Segphos, Difluorphos, P-Phos, etc.), giving bicyclic enones II (3a–x; X = O, NBoc, CH₂; R = Me, Cy, PhCH₂, BocNHCH₂CH₂, alkoxy, CH₂:CH, Ph, MeO₂CCH₂, haloalkyl, aryl); the products 3 were obtained with >90% ee, either as pure diastereomer or with (15-20):1 ratio of (3S,3aR,7aR):(3S,3aS,7aS) diastereomers. The requisite allenyl-tethered cyclohexadienones 1a–r were prepared by oxidative etherification of phenols 4-RC₆H₄OH with propargyl alc. CHCCH₂OH to give cyclohexadienone propargyl ethers HCCCH₂O(R)(CH:CH)₂CO with subsequent CuBr-catalyzed formaldehyde addition Through regioselective β-silylation of the allene and subsequent enantioselective 1,4-addition to cyclohexadienone, this tandem reaction could afford cis-hydrobenzofuran, cis-hydroindole, and cis-hydroindene frameworks with excellent yields (80-98%) and enantioselectivities (94-98 % ee) bearing vinylsilane and enone substructures. Meanwhile, this mild transformation is generally compatible with a wide range of functional groups, which allows further conversion of the bicyclic products to bridged and tricyclic ring structures.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Formula: C38H24F4O4P2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Takahashi, Masashi published the artcileAtropisomeric lactam chemistry: catalytic enantioselective synthesis, application to asymmetric enolate chemistry and synthesis of key intermediates for NET inhibitors, HPLC of Formula: 503538-69-0, the publication is Tetrahedron (2010), 66(1), 288-296, database is CAplus.

In the presence of an (R)-SEGPHOS and Pd(OAc)₂ catalyst system, the intramol. N-arylation of ortho-tert-butyl-NH-anilides possessing an iodophenyl group, e.g., I, proceeded in a highly enantioselective manner (89-98% ee) to give optically active atropisomeric lactams, e.g., II, having an N-C chiral axis. MPLC purification of the enantio-enriched lactam products using an achiral silica gel column led to a further increase in the enantiomeric purity (>99% ee). The reaction of the lithium enolate prepared from the optically active atropisomeric lactam with various alkyl halides gave α-substituted and α,α-disubstituted lactam products with high diastereoselectivity. α-Alkylated lactam derivatives were efficiently converted to key intermediates for the synthesis of a norepinephrine transporter inhibitor.

Tetrahedron published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C6H12N2O, HPLC of Formula: 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Inoue, Hiroo published the artcilePhoto-oxidation of glycols in the liquid phase, Application of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Kogyo Kagaku Zasshi (1966), 69(4), 654-7, database is CAplus.

The products produced by the irradiation of the ethylene glycol and its derivative with 100 w. high-pressure Hg-vapor lamp in the atm. of O or N, were studied with a gas chromatograph and paper-partition chromatography. In the case of ethylene glycol, AcH, acetaldehyde ethylene acetal, AcOEt and MeOH were identified. Acetone and its ketal and iso-PrOH were obtained in the case of propylene glycol. The dehydrogenation was thought to be predominant in the initial stage of the reaction. On the other hand, the photo-oxidation took place even when the hydroxy group of ethylene glycol was protected by etherification. Ethylene glycol monoacetate was produced from acetaldehyde ethylene acetal. HCHO, formic acid, and Me formate were formed from ethylene glycol monomethyl ether and dimethyl ether.

Kogyo Kagaku Zasshi published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Application of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wang, Mengcen published the artcileEffects of different classes of attractants, cochliophilin A and N-(E)-feruloyl-4-O-methyldopamine, on the response of Aphanomyces cochlioides zoospores in their chemoattraction and activation of motility linked with intracellular cAMP, Recommanded Product: 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, the publication is Journal of Pesticide Science (Tokyo, Japan) (2013), 38(4), 181-187, database is CAplus.

Cochliophilin A (5-hydroxy-6,7-methylenedioxyflavone) (1) and N-(E)-feruloyl-4-O-methyldopamine (2) are naturally occurring host-specific chemoattractants for Aphanomyces cochlioides zoospores. In a cross-competition assay, compound 1 (4fmol) applied to diatomite particles clearly attracted A. cochlioides zoospores in an aqueous solution of excessive compound 2 (1 × 10^-6 M) that could mask a concentration gradient of 1 dispersed from the particles. Similarly, 2 (40fmol) on particles also attracted A. cochlioides zoospores in an aqueous solution of 1 (1 × 10^-6 M). In addition, compound 2 on the particles did not attract the zoospores in an aqueous solution containing 1 × 10^-6 M NADP⁺, while 1 clearly attracted zoospores in the same solution These results allowed us to speculate that compounds 1 and 2 do not share receptors. The chemosensory system for 1 is probably for host recognition of A. cochlioides zoospores, while the system for 2 is linked to cell differentiation.

Journal of Pesticide Science (Tokyo, Japan) published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C12H15NO4, Recommanded Product: 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Lee, Sang Bong published the artcileN-Benzylpyridinium salts as new useful catalysts for transformation of epoxides to cyclic acetals, ortho esters, and ortho carbonates, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Chemistry Letters (1990), 2019-22, database is CAplus.

Epoxides react with aldehydes, ketones, lactones, and carbonates in the presence of N-(4-methoxybenzyl)-2-cyanopyridinium hexafluoroantimonate (I) under mild conditions to give cyclic acetals, ortho esters, and ortho carbonates. Thus, Me₂CO was treated with styrene oxide in the presence of I at room temperature for 10 min. to give 93% dimethylphenyldioxolane II.

Chemistry Letters published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem