Dioxole related

Yang, Qingjing published the artcileKinetic Resolution and Dynamic Kinetic Resolution of Chromene by Rhodium-Catalyzed Asymmetric Hydroarylation, Application of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Angewandte Chemie, International Edition (2019), 58(16), 5343-5347, database is CAplus and MEDLINE.

A highly efficient kinetic resolution and dynamic kinetic resolution of chromene was reported for the first time and they proceeded by a rhodium-catalyzed asym. hydroarylation pathway. This new approach offered versatile access to various chiral 2,3-diaryl-chromanes containing vicinal stereogenic centers, as well as the recovered chiral flavenes, in high yields with excellent ee values (s factor up to 532). Particularly noteworthy was that this strategy could be further extended to the establishment of a dynamic version of the kinetic resolution of chromene acetals and allowed complete access to chiral isoflavanes and α-aryl hydrocoumarins.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C39H35N5O8, Application of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zhang, Shi-Meng published the artcileChemical Constituents of the Seeds of Celosia cristata, Category: dioxole, the publication is Chemistry of Natural Compounds (2016), 52(5), 827-829, database is CAplus.

Phytochem. investigation of the seeds of Celosia cristata led to the isolation of a new phenolic compound, celosialdehyde (10, I), together with 21 known compounds including seven phenolic compounds, four flavonoids, three fatty acids, three saponins, two glycerides, one steroid, and one triterpenoid. The structures of these compounds were characterized and identified by spectral analyses. To the best of our knowledge compounds 2, 7-10, 13, and 15-22 were isolated from this plant for the first time.

Chemistry of Natural Compounds published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C12H9N3O4, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Huang, Shi-jie published the artcileQuality control of tobacco flavor by GC-MS combined with clustering analysis, COA of Formula: C11H14O4, the publication is Anhui Nongye Kexue (2009), 37(14), 6344-6346, database is CAplus.

[Objective] The research aimed to establish the GC-MS fingerprint of tobacco flavor A# and provide new methods for the quality control of tobacco flavor. [Method] Eight batches of tobacco flavor A# were determined by GC-MS combined with clustering anal. [Result] The fingerprints of tobacco flavor A#, including 23 mutual peaks were developed after determination of 6 batches of flavor according to the clustering anal. [Conclusion] The separation effect of peaks in fingerprints is better and the characteristic is also obvious. The RSD values of precision and reproducibility are less than 3%. This method can be used for the quality control of tobacco flavor.

Anhui Nongye Kexue published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, COA of Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Praetorius, Jeremy M. published the artcileBenzimidazoles as Ligands in the Ruthenium-Catalyzed Enantioselective Bifunctional Hydrogenation of Ketones, Category: dioxole, the publication is Organometallics (2010), 29(3), 554-561, database is CAplus.

A series of Cl₂Ru(diphosphane)L₂ (II) complexes in which L = N1-alkylated benzimidazoles, bonding to the metal through nitrogen, have been synthesized and characterized. In the case of 1-methylbenzimidazole, the resulting complexes exist as statistical mixtures of all possible conformational isomers. When the size of the substituent on the benzimidazole was increased to trityl, complexes could be prepared that exist as a single diastereomer. All complexes possessing benzimidazole ligands bound to the ruthenium center are active for the mild and chemoselective hydrogenation of ketones in the presence of alkenes. Catalysts that exist as a single diastereomer, prepared with enantiomerically pure diphosphanes, catalyze the hydrogenation of prochiral ketones with moderate levels of enantioselectivity that are significantly improved relative to catalysts existing in several conformations.

Organometallics published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Luo, Zhi-chen published the artcileSyhthesis of vanillin 1, 2-propylene glycol acetal with copper p-toluene sulfonate catalyst, COA of Formula: C11H14O4, the publication is Huaxue Shijie (2010), 51(11), 675-677, database is CAplus.

Vanillin-1,2-propylene glycol acetal was synthesized from vanillin and 1,2-propylene glycol using copper p-toluene sulfonate as catalyst and benzene as water stripping agent. The effects of molar ratio of the reactants, catalyst dosage and reaction time on yield were investigated. Copper p-toluene sulfonate showed high catalytic activity, and the catalyst was reused for 3 times. The preferential conditions are as follows: based on 15.2g(0.1 mol) of vanillin, the molar ratio of vanillin to 1,2-propylene glycol is 1: 1.60; the dosage of catalyst is 0.9g, the amount of benzene as water stripping agent is 25 mL; and the reaction time is 2.5 h. The yield can achieve 87%.

Huaxue Shijie published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, COA of Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Yang, Zhiping published the artcileEnantioselective Palladium-Catalyzed Hydrophosphinylation of Allenes with Phosphine Oxides: Access to Chiral Allylic Phosphine Oxides, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Angewandte Chemie, International Edition (2021), 60(52), 27288-27292, database is CAplus and MEDLINE.

A Pd-catalyzed hydrophosphinylation of alkyl and aryl-oxyallenes with phosphine oxides has been developed for the efficient and rapid construction of a family of chiral allylic phosphine oxides with a diverse range of functional groups. This methodol. was further applied in the facile construction of chiral 2H-chromene and later stage functionalization of cholesterol.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C9H9ClN2, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

He, Si-Qing published the artcilePreparation of carboxyethyltin group-functionalized highly ordered mesoporous organosilica composite material with double acid sites, Name: 1,4-Dioxaspiro[4.5]decane, the publication is Journal of Materials Science (2019), 54(6), 4601-4618, database is CAplus.

A series of highly ordered mesoporous ethane-bridged organosilica composite materials functionalized by carboxyethyltin group, SnR-Si(Et)Si-X (SnR and Si(Et)Si denote [Sn(CH₂)₂COOH]³⁺ and ethane-bridged organosilica groups, resp.), were successfully designed through one-step co-condensation-hydrothermal method. The pore morphol. and textural properties, Sn(IV) coordination environment, the type of acid site, Bronsted and Lewis acid strength were systematically characterized by LXRD, TEM observation, N₂ porosimetry measurements, MAS NMR (²⁹Si, ¹³C, ¹¹⁹Sn), UV-Vis diffuse reflectance spectrum, as well as ¹H and ³¹P MAS NMR, FT-IR anal. of adsorbed pyridine, acid-base titration Composite materials SnR-Si(Et)Si-X possess Bronsted and Lewis acid sites, which originates from -COOH in [Sn(CH₂)₂COOH]³⁺ group and bridging OH in [Si(OH)SnR] group as well as tetrahedral coordination framework Sn(IV) in the open configuration [SnR(SiO)₃(OH)], resp. The above 2D hexagonal mesoporous structure with unique textural properties, double acid sites (Bronsted and Lewis acid sites) and hydrophobic surface make SnR-Si(Et)Si-X exhibit excellent acid catalytic activity, reusability and water tolerance toward ketalization of cyclohexanone with glycol in absence of azeotrope agent at low temperature

Journal of Materials Science published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Name: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Li, Guixian published the artcileEfficient and highly-selective cycloaddition of epoxides with carbonyl compound over Wells-Dawson type heteropolyacids, COA of Formula: C6H12O2, the publication is Journal of Molecular Catalysis A: Chemical (2005), 236(1-2), 72-76, database is CAplus.

Wells-Dawson type Heteropolyacids (H_6+nP₂Mo_18-nV_nO₆₂) (n = 0-2, 4) have proved to be efficient heterogeneous catalysts for the reaction of epoxides with carbonyl compounds to form 1,3-dioxolane derivatives Especially, when H₇P₂Mo₁₇VO₆₂ was used to catalyze the reaction between acetone and epoxypropane, the selectivity to 1,3-dioxolane reached to 93.3% with nearly complete conversion of epoxide and 1.1 × 10⁴ h^-1 of TOF.

Journal of Molecular Catalysis A: Chemical published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, COA of Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Ghosh, Avipsa published the artcileCoupling Catalytic Alkene Hydroacylation and α-Arylation: Enantioselective Synthesis of Heterocyclic Ketones with α-Chiral Quaternary Stereocenters, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is ACS Catalysis (2016), 6(4), 2673-2680, database is CAplus.

We report a strategy that combines alkene hydroacylation and enantioselective α-(hetero)arylation reactions to form a wide variety of nitrogen-containing heterocyclic ketones bearing α-chiral quaternary stereogenic centers. Exo-selective, intramol. Ni-catalyzed hydroacylations of N-homoallylindole- and N-homoallylpyrrole-2-carboxaldehydes form α-substituted six-membered heterocyclic ketones in up to 95% yield, while N-heterocyclic carbene (NHC) catalyzed hydroacylations of N-allylindole- and N-allylpyrrole-2-carboxaldehydes form α-substituted five-membered heterocyclic ketones in up to 99% yield. The racemic five- and six-membered products of Ni- and NHC-catalyzed hydroacylation reactions are readily transformed into heterocyclic ketones containing an α-chiral quaternary stereogenic center by enantioselective Ni-catalyzed α-arylation and α-heteroarylation reactions. The chiral, nonracemic products formed through a combination of alkene hydroacylation and α-(hetero)arylation reactions are formed in moderate to high yields (44-99%) with excellent enantioselectivities (typically >95% ee). The identity of the precatalyst for Ni-catalyzed α-(hetero)arylation is dictated by the identity of the α-substituted heterocyclic ketone starting material. α-(Hetero)arylations of six-membered heterocyclic ketones occur at 65-85 °C in the presence of a catalyst generated in situ from Ni(COD)₂ and (R)-BINAP or (R)-DIFLUORPHOS. α-(Hetero)arylation of five-membered heterocyclic ketones must be conducted at room temperature in the presence of an [((R)-BINAP)Ni(η²-NC-Ph)] precatalyst or a catalyst generated in situ from Ni(COD)₂, (R)-DIFLUORPHOS, and benzonitrile.

ACS Catalysis published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Naodovic, Marina published the artcileEnantioselective Ag-catalyzed allylation of aldimines, Related Products of dioxole, the publication is European Journal of Organic Chemistry (2009), 5129-5131, database is CAplus and MEDLINE.

A highly enantioselective synthesis of homoallylic amines, using allyltrimethoxysilane under Ag^I catalytic conditions, has been developed. Among the chiral ligands investigated, a remarkable difference in the resulting Ag^I complexes was observed Under mild conditions and low catalyst loadings, homoallylamines were produced in high ee values (up to 80%) and good yields. The methodol. can be further extended to a diastereoselective and enantioselective crotylation of aldimines. © Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009.

European Journal of Organic Chemistry published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Related Products of dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem