Dioxole related

Fernando, Ganwarige Sumali N. published the artcileApplication of an Ultrasound-Assisted Extraction Method to Recover Betalains and Polyphenols from Red Beetroot Waste, Quality Control of 110204-45-0, the publication is ACS Sustainable Chemistry & Engineering (2021), 9(26), 8736-8747, database is CAplus.

Agriculture and food industries generate substantial quantities of waste material with a huge potential for bioactive ingredients to be recovered and converted into high-value chems. Red beetroot, known for its high content in betalains, natural red pigments, as well as polyphenols, fiber, and nitrate, is experiencing increasing demand, in particular as juice, which is leaving behind large amounts of waste. The present study focused on the recovery of betalains and polyphenols from dried whole beetroot and wet and dried beet pulp waste from the juicing industry. As part of an ultrasound-assisted extraction, ethanol/water-based solvent mixtures were used as they were found to be more effective than single solvents. Enzyme-assisted extraction was initially examined in the case of wet pulp but was not able to retain betalains. Betalains appear to be more stable in dried pulp. Ultrasound-assisted extraction was found to be more suitable to effectively extract both betalains and polyphenols with a high bioactive yield from dried pulp. The total betalain and polyphenol profiles as well as storage stability and antioxidant capacities were evaluated over a period of four weeks after extraction from the dried waste. During the four-week storage, betalains quickly degraded at room temperature in contrast to -20°C, whereas polyphenols and antioxidative activity were much less influenced by temperature When compared, dried samples from the beetroot juicing industry demonstrate good betalain and polyphenol extractability; thus, these data indicate that dried beet waste can serve as a good source of betalains for the color industry and other technol. sectors.

ACS Sustainable Chemistry & Engineering published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, Quality Control of 110204-45-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Scharf, Hans D. published the artcileSynthesis of furan derivatives from 4-benzoyloxy-1,3-dioxolane derivatives, Formula: C6H12O2, the publication is Angewandte Chemie (1976), 88(21), 718, database is CAplus.

Pyrolysis of dioxolanes I [R = H, R1 = Me, R2 = H, R1 = Et, R2 = Me, R1R2 = (CH2)3, (CH2)4; R = R1 = Me, R2 = H] at 230° 1.5 hr gave o-MeC6H4CO2H and 70-90% furans II. At 400°/10-3 Torr, 30-5% dioxolanes III were obtained but no II.

Angewandte Chemie published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kwiatkowski, Stefan published the artcileReactions of 1,3-dioxacyclanes with acid halides. A new synthesis for ω-halohydrin esters, Synthetic Route of 1193-11-9, the publication is Monatshefte fuer Chemie (1984), 115(6-7), 869-72, database is CAplus.

Dioxolanes I (R = R¹ = H, Me, Et; R² = H, R³ = H, Me, pentyl; R = R² = R³ = Me, R¹ = Ph) reacted with R⁴CH₂COBr (R⁴ = H, Cl) to give halohydrin esters BrCHR²CHR³O₂CCH₂R⁴ in 53-85% yield. Similarly, dioxanes II (R⁵ = Me, Et) and acyl halides R⁴CH₂COR⁶ (R⁴ = H, Cl; R⁶ = Cl, Br) gave 40-75% R⁶CH₂CH₂O₂CCH₂R⁴.

Monatshefte fuer Chemie published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Synthetic Route of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Alvarez-Martin, Alba published the artcileInvestigation of volatile organic compounds in museum storage areas, Application of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Air Quality, Atmosphere & Health (2021), 14(11), 1797-1809, database is CAplus.

This study investigates the complex mixture of volatile organic compounds (VOCs) released by and accumulated within a collection of historic medicinal, pharmaceutical, and cosmetic artifacts housed at the National Museum of American History (Smithsonian Institution). In recent years, staff have become concerned, both for the safety of the objects and for personnel working in the collection, about strong unremediated odors accumulating within several storage cabinets. Museum staff also wondered if non-odorous off-gassing might need remediation. Solid-phase microextraction combined with gas chromatog.-mass spectrometry anal. (SPME-GC-MS) was used to identify VOCs present in the storage room housing the collection. Over 160 compounds were detected and identified overall. Among these, 49 appeared to be directly related to ingredients used in the manufacture of many collection items. The results of the study suggest that SPME-GC-MS can be a strong tool for the rapid screening of multicomponent museum collections exhibiting off-gassing problems, before the pursuit of other more tedious anal. approaches. Addnl., the study reveals valuable insight into the characteristic volatile emission of historic medicinal, pharmaceutical, and cosmetic artifacts, increasing understanding of, and decision-making for, similar collections of objects. Eventually, it is hoped that this information can be used to inform mitigation strategies for the capture and reduction of VOCs in collections storage areas.

Air Quality, Atmosphere & Health published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Application of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Liao, Xuebin published the artcileEnantioselective α-Arylation of Ketones with Aryl Triflates Catalyzed by Difluorphos Complexes of Palladium and Nickel, Name: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Journal of the American Chemical Society (2008), 130(1), 195-200, database is CAplus and MEDLINE.

The asym. α-arylation of ketones with aryl triflates is described, and the use of this electrophile with nickel and palladium catalysts containing a segphos derivative increases substantially the scope of highly enantioselective arylations of ketone enolates. The combination of aryl triflates as reactant, difluorphos as ligand, palladium catalysts for reactions of electron-neutral or electron-rich aryl triflates, and nickel catalysts for reactions of electron-poor aryl triflates led to a series of α-arylations of tetralone, indanone, cyclopentanone, and cyclohexanone derivatives Enantioselectivities ranged from 70% to 98% with 10 examples over 90%. Systematic studies on these α-arylations have revealed a number of factors that affect enantioselectivity. Ligands containing biaryl backbones with smaller dihedral angles generate catalysts that react with higher enantioselectivity than related ligands with larger dihedral angles. In addition, faster rates for reactions of aryl triflates vs. those for reactions of aryl bromides allow the α-arylations of aryl triflates to be conducted at lower temperatures, and this lower temperature improves enantioselectivity. Finally, studies that compare the enantioselectivities of catalytic reactions to those of stoichiometric reactions of isolated [(segphos)Pd(Ar)(Br)], [(segphos)Pd(Ar)(I)], and [(segphos)Ni(C₆H₄CN-4)Br] suggest that catalyst decomposition affects enantioselectivity.

Journal of the American Chemical Society published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Name: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zhang, Du published the artcileReuse of waste catalytic-cracking catalyst: fine performance in acetalization, Synthetic Route of 177-10-6, the publication is Journal of Material Cycles and Waste Management (2020), 22(1), 22-29, database is CAplus.

Equilibrium fluid-catalytic-cracking catalyst (E-cat), a waste catalyst from fluid-catalytic cracking in petroleum refining, was used to catalyze acetalization of aldehydes (ketones) with diols. Although the activity of E-cat in catalytic cracking has decreased, it still presented fine catalytic performance in the acetalization. The ketal was stoichiometrically formed in the reaction of cyclohexanone with ethanediol, conversion of the ketone reached to 99.7% and selectivity of the ketal maintained 100% in the optimum conditions. It was revealed that E-cat can be provided with the wide adaptability in acetalization from the syntheses of different kinds of acetals or ketals. Moreover, E-cat appeared a superreusability through filtration from the reaction flask. It was an attracted example for decrement from the bulk waste catalyst in petroleum refining.

Journal of Material Cycles and Waste Management published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C38H74Cl2N2O4, Synthetic Route of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Lu, Yao published the artcileCharacterization of a bio-oil from pyrolysis of rice husk by detailed compositional analysis and structural investigation of lignin, Category: dioxole, the publication is Bioresource Technology (2012), 114-119, database is CAplus and MEDLINE.

Detailed compositional anal. of a bio-oil (BO) from pyrolysis of rice husk was carried out. The BO was extracted sequentially with n-hexane, CCl₄, CS₂, benzene and CH₂Cl₂. In total, 167 organic species were identified with GC/MS in the extracts and classified into alkanes, alcs., hydroxybenzenes, alkoxybenzenes, dioxolanes, aldehydes, ketones, carboxylic acids, esters, nitrogen-containing organic compounds and other species. The benzene ring-containing species (BRCCs) were attributed to the degradation of lignin while most of the rests were derived from the degradation of cellulose and hemicellulose. Along with guaiacyl and p-hydroxyphenyl units as the main components, a new type of linkage was suggested, i.e., C_ar-CH₂-C_ar in 4,4′-methylenebis(2,6-dimethoxyphenol). Based on the species identified, a possible macromol. structure of the lignin and the mechanism for its pyrolysis are proposed. The BO was also extracted with petroleum ether in ca. 17.8% of the extract yield and about 82.1% of the extracted components are BRCCs.

Bioresource Technology published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wang, Cong-Shuai published the artcileAsymmetric Synthesis of Axially Chiral Naphthyl-C3-indoles via a Palladium-Catalyzed Cacchi Reaction, Formula: C38H24F4O4P2, the publication is Organic Letters (2021), 23(19), 7401-7406, database is CAplus and MEDLINE.

Atropoisomeric biaryl motifs are widely found in natural products and bioactive compounds as well as chiral catalysts and ligands. Various efficient approaches have been disclosed for the construction of chiral six-six biaryl skeletons. In contrast, the enantioselective synthesis of axially chiral arylindoles through the strategy of de novo construction, other than the asym. functionalization of indoles, remain a challenging task. Herein authors report an efficient Pd(0)/(S)-Segphos-catalyzed atroposelective Cacchi reaction of 2-alkynylanilines with sterically congested naphthyl halides, which afforded an array of naphthyl-C3-indoles in high yields with good to excellent atroposelectivities. The addition of water and the modulation of the manipulation procedure by premixing the palladium complex and the naphthyl halide were the keys to success. The conformational stability of the obtained axially chiral naphthyl-C3-indole containing a synthetically more-valuable free NH moiety is revealed through kinetic experiments

Organic Letters published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C6H5F4NO3S, Formula: C38H24F4O4P2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zhu, Zai-ming published the artcileSynthesis of cyclohexanone ethylene ketal catalyzed by Keggin-type Ni/Cu/2,2′-H₂ biim-tungstosilicates, Application of 1,4-Dioxaspiro[4.5]decane, the publication is Yingyong Huagong (2015), 44(5), 882-886, 889, database is CAplus.

A series of Keggin-type Ni/Cu/H₂biim-tungstosilicates (H₂ biim = 2,2′-biimidazole) were synthesized with the parent tungstosilicic acid as a reactant and H₂ biim, Ni²⁺/Cu²⁺ and their complexes as raw materials by a direct precipitation method. They were characterized by single crystal XRD, IR and elemental anal. The acid-catalyzed synthesis of cyclohexanone ethylene ketal by the reaction of cyclohexanone with ethylene glycol was selected as a model reaction. The catalytic activities of these tungstosilicates were investigated. The results show that the introduction of large cation reduced the POM’s solubility, and the catalysts can be recycled and reused, so that their utilization can be improved. Moreover, the catalytic activities of these heterogeneous catalysts were almost unchanged after three cycles.

Yingyong Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C15H23BO2, Application of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Li, Zi-Liang published the artcileThree molybdophosphates based on Strandberg-type anions and Zn(II)-H₂biim/H₂O subunits: syntheses, structures and catalytic properties, Recommanded Product: 1,4-Dioxaspiro[4.5]decane, the publication is Dalton Transactions (2014), 43(15), 5840-5846, database is CAplus and MEDLINE.

Three new inorganic-organic hybrid compounds based on Strandberg-type anions and Zn(II)-H₂biim/H₂O subunits, namely {H₄(H₂biim)₃}[Zn(H₂biim)(H₃biim)(H₂O)(HP₂Mo₅O₂₃)]₂·3H₂O (1), {H₉(H₂biim)₇}[(μ-biim){(Zn(H₂O)₂)_0.5(HP₂Mo₅O₂₃)}₂]·7H₂O (2) and {H₇(H₂biim)₇}[Zn(H₂biim)(H₂O)₂(HP₂Mo₅O₂₃)][H₂P₂Mo₅O₂₃]·8H₂O (3) (H₂biim = 2,2′-biimidazole), have been synthesized in aqueous solutions and characterized. They were also used as efficient and reusable catalysts for the protection of carbonyl compounds Their fascinating structural features are that mono Zn(II)-supporting biphosphopentamolybdate ({P₂Mo₅}) clusters exist in their crystal structures, and the nitrogen donor ligand H₂biim exhibits three different coordination modes in these three compounds, resp.: for 1, two 2,2′-biimidazole mols., as mono- and bidentate ligands coordinate to the same Zn(II) ion; for 2, one bi-neg. tetradentate ligand μ-biim bridges two Zn(II) ions, while for 3, one neutral bidentate H₂biim ligand links one Zn(II) ion. Most importantly, compounds 1–3 represent the first example where Strandberg-type POMs are used as acid-catalysts in an organic reaction.

Dalton Transactions published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Recommanded Product: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem