Islam, M. Tofazzal published the artcileRepellent activity of estrogenic compounds toward zoospores of the phytopathogenic fungus Aphanomyces cochlioides, Synthetic Route of 110204-45-0, the publication is Zeitschrift fuer Naturforschung, C: Journal of Biosciences (2001), 56(3/4), 253-261, database is CAplus and MEDLINE.
Bisphenol A, showed potent repellent activity against the zoospores of Aphanomyces cochlioides. Based on this finding, a number of androgenic and estrogenic compounds (e.g. testosterone, progesterone, estradiols, diethylstilbestrol, estrone, estriol, pregnenolone, dienestrol etc.) were tested on the motility behavior of A. cochlioides zoospores. Most of the estrogenic compounds exhibited potent repellent activity (1 μg/mL or less by the “particle method”) toward the motile zoospores of A. cochlioides. The authors derivatized some of the estrogens and discussed the relationship between the structure of active mols. and their repellent activity. Aromatization of the A ring with a free hydroxyl group at C-3 position of a steroidal structure is necessary for higher repellent activity. Methylation of diethylstilbestrol (DES) yielded completely different activity i.e. both mono- and di-Me ethers of DES showed attractant activity. The attracted zoospores were encysted and then germinated in the presence of di-Me ether of DES. The potential usefulness of this repellent test is discussed for the detection of estrogenic activity of naturally occurring compounds, and the possible role of phytoestrogens in host/parasite interactions.
Zeitschrift fuer Naturforschung, C: Journal of Biosciences published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, Synthetic Route of 110204-45-0.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem