Category: Dioxole

Synthesis of acetals and ketals catalyzed by dibutyltin(IV) sulfonates was written by Zhao, Li-Fang;Wang, Hong-She;Miao, Jian-Ying. And the article was included in Youji Huaxue in 2008.COA of Formula: C8H14O4 The following contents are mentioned in the article:

A method for the synthesis of the above-mentioned title catalysts [i.e., (benzenesulfonate-κO,κO‘)dibutyltin and (methanesulfonate-κO,κO‘)dibutyltin] is reported here. A reaction of dibutyltin oxide with benzenesulfonic acid or methanesulfonic acid gave two dibutyltin(IV) sulfonates which were used as the catalysts for the synthesis of acetals and ketals. The optimal reaction conditions were obtained by orthogonal experiments The advantages of the present procedure are high yields and short reaction time. Furthermore, the catalysts could be recovered easily by filtration and reused efficiently. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1COA of Formula: C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.COA of Formula: C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Highly efficient acetalization and ketalization catalyzed by cobaloxime under solvent-free condition was written by Zong, Yang;Yang, Liting;Tang, Shanyu;Li, Longjia;Wang, Wanjie;Yuan, Bingxin;Yang, Guanyu. And the article was included in Catalysts in 2018.Related Products of 6413-10-1 The following contents are mentioned in the article:

An efficient catalytic system was developed for the acetalization and ketalization of carbonyl compounds with polyhydric alcs. under mild solvent-free conditions. In the presence of 0.1 mol% CoCl₂ and 0.2 mol% dimethylglyoxime at 70° under 5 KPa pressure for 1 h, 95.3% conversion of cyclohexanone and 100% selectivity of the corresponding cyclic ketal could be obtained, where TOF reached as high as 953 h^-1. It is proposed that the in situ generated planar tetracoordinate cobaloxime played the key role in the catalytic cycle and was responsible for the excellent catalytic performance. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Related Products of 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Related Products of 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of fructone catalyzed by water-soluble Bronsted acid ionic liquids was written by Wang, Yuan Yuan;Wang, Rong;Wu, Liang Chun;Dai, Li Yi. And the article was included in Chinese Chemical Letters in 2007.COA of Formula: C8H14O4 The following contents are mentioned in the article:

Fructone (2-methyl-2-ethylacetoacetate-1,3-dioxolane), a flavoring material, was synthesized from Et acetoacetate and glycol using five water-soluble Bronsted acid ionic liquids as catalysts for the first time. The used Bronsted acid ionic liquids include [Hmim]Tfa, [Hmim]Tsa, [Hmim]BF₄, [Bmim]HSO₄, and [Bmim]H₂PO₄, and [Hmim]BF₄ showed the highest catalytic activity for the preparation of fructone. After reaction, the product could be isolated from the reaction system automatically, and the ionic liquid could be directly reused without dehydration. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1COA of Formula: C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.COA of Formula: C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents was written by Perlikova, Pavla;Konecny, Petr;Naus, Petr;Snasel, Jan;Votruba, Ivan;Dzubak, Petr;Pichova, Iva;Hajduch, Marian;Hocek, Michal. And the article was included in MedChemComm in 2013.Synthetic Route of C14H16ClN3O4 The following contents are mentioned in the article:

Title 6-alkyl-, 6-aryl- and 6-hetaryl-7-deazapurine ribonucleosides previously known as nanomolar cytostatics were found to be potent inhibitors of either human or mycobacterial (MTB) adenosine kinase (ADK). Several new derivatives bearing bulky substituents at position 6 were non-cytotoxic but selectively inhibited MTB ADK. However, most of the nucleosides (ADK inhibitors) as well as their octadecylphosphate prodrugs were inactive in the whole cell assay of inhibition of Mycobacterium bovis growth. 6-Methyl-7-deazapurine ribonucleoside was found to be a potent antimycobacterial agent. This study involved multiple reactions and reactants, such as ((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol (cas: 158078-04-7Synthetic Route of C14H16ClN3O4).

((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol (cas: 158078-04-7) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C14H16ClN3O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of fructone over phosphotungstic acid – silica catalysts prepared by sol – gel method was written by Zhang, Fumin;Zhong, Yijun;Zhu, Weidong;Wang, Jun. And the article was included in Shiyou Huagong in 2007.Quality Control of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:

A series of phosphotungstic acid-silica gel catalysts (PW/SG) were prepared by sol – gel method. The catalytic performances of the catalysts were investigated in synthesis of fructone y liquid phase acetalization of Et acetoacetate (I) with ethylene glycol (EG) in a batch reactor. 40% PW/SG catalyst exhibits the best catalytic performance among these catalysts. The optimal reaction conditions are as follows: molar ratio I/EG 1: 1.2, catalyst mass fraction in reactants 0.36%, volume fraction of cyclohexane as water removal agent in reaction medium 30%, reaction temperature 383 K and reaction time 90 min. In this case, conversion of I can reach 95.5% and selectivity to fructone is ≥97%. Catalyst stability experiment show that the high catalytic activity of 40% PW/SG can be maintained and high conversion of 95.0% can be kept even after reusing the catalyst for 5 times. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Quality Control of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Quality Control of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Method for Predicting Odor Intensity of Perfumery Raw Materials Using Dose-Response Curve Database was written by Wakayama, Hideki;Sakasai, Mitsuyoshi;Yoshikawa, Keiichi;Inoue, Michiaki. And the article was included in Industrial & Engineering Chemistry Research in 2019.Electric Literature of C8H14O4 The following contents are mentioned in the article:

The main purpose of this study is to facilitate fragrance development on the basis of scientific knowledge. To this end, data on 314 perfumery raw materials (PRMs) showing the relationship between PRM odor intensity and gas concentration were obtained, and a calculation model for the data was then developed with the following features: (1) maximum PRM coverage, (2) calculating values implying odor intensity from only arbitrary gas concentration, and (3) estimating odor intensity from the calculated values directly and easily. To verify the prediction accuracy of this model, the predicted odor intensity was compared with the evaluated value for both single component and a mixture, and the same degree of root mean square error (RMSE) was confirmed. RMSE in the single component was 6.22 while that in the mixture was 6.69. Thus, the odor intensity of a PRM or mixture can be predicted from arbitrary gas concentrations This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Electric Literature of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Electric Literature of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of SO^2-₄/TiO₂-La₂O₃ solid superacid and its catalytic activities in acetalation and ketalation was written by Yang, Shui-jin;Bai, Ai-min;Sun, Ju-tang. And the article was included in Journal of Zhejiang University, Science, B in 2006.SDS of cas: 6413-10-1 The following contents are mentioned in the article:

SO^2-₄/TiO₂-La₂O₃, a novel solid superacid, was prepared and its catalytic activities at different synthetic conditions are discussed with esterification of n-butanoic acid and Bu alc. as probing reaction. The optimum conditions have also been found, mole ratio of n(La³⁺):n(Ti⁴⁺) is 1:34, the soaked consistency of H₂SO₄ is 0.8 mol/L, the soaked time of H₂SO₄ is 24 h, the calcining temperature is 480 °C, the calcining time is 3 h. Then it was applied in the catalytic synthesis often important ketals and acetals as catalyst and revealed high catalytic activity. Under these conditions on which the molar ratio of aldehyde/ketone to glycol is 1:1.5, the mass ratio of the catalyst used in the reactants is 0.5%, and the reaction time is 1.0 h, the yields of ketals and acetals can reach 41.4%∼95.8%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1SDS of cas: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.SDS of cas: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of heterogeneous mesoporous silica-supported 12-tungstophosphoric acid catalyst and its catalytic performance was written by Guo, Hong-qi;Mao, Ming-fu;Ni, Zhong-bin;Chen, Ming-qing;Liu, Shi-rong. And the article was included in Fenzi Cuihua in 2011.Synthetic Route of C8H14O4 The following contents are mentioned in the article:

12-Tungstophosphoric acid was supported on SBA-15 and amine-modified SBA-15 by impregnation. The structure and properties of the catalyst were characterized by FT-IR spectroscopy, X-ray diffraction, N₂ adsorption-desorption, TEM, Raman spectra and NH₃-TPD technol. The result confirmed the mesostructure for SBA-15 and the Keggin structure of the heteropolyanions was preserved. However, aggregation occurred in the high loading, and because of the pore blockage, the BET surface area, pore volume and pore diameter decreased obviously. The tungstophosphoric acid can disperse in the pore of the support SBA-15/NH₂, but the acidity of the catalyst reduced. The catalytic activities of the catalysts were evaluated for the esterification reaction of Et acetoacetate and ethylene glycol and the catalysts supported on amine-modified SBA-15 show excellent reusability and selectivity. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Synthetic Route of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of acetals and ketals with I₂/PAn was written by Yang, Shuijin;Tong, Wenlong;Yin, Guojun. And the article was included in Beijing Keji Daxue Xuebao in 2006.COA of Formula: C8H14O4 The following contents are mentioned in the article:

A new environmental friendly catalyst, I₂/Pan, was prepared The catalytic activities of I₂/PAn in synthesizing 2-methyl-2-ethoxycarbonylmethyl-1, 3-dioxolane, 2, 4-dimethyl-2-ethoxycarbonylmethyl-1, 3-dioxolane, cyclohexanone ethylene ketal, cyclohexanone 1,2-propanediol ketal, butanone ethylene ketal, butanone 1, 2-propanediol ketal, 2-phenyl-1, 3-dioxolane, 4-methyl-2-phenyl-1, 3-dioxolane, 2-propyl-1, 3-dioxolane, and 4-methyl-2-propyl-1, 3-dioxolane were reported. It is demonstrated that I₂/PAn is an excellent catalyst. Various factors concerned in these reactions were investigated. An optimum condition was found, i.e., the molar ratio of aldehyde/ketone to glycol is 1/1.6, the mass ratio of the catalyst used to the reactants is 0.2%, and the reaction time is 1.0 h. Under the optimum condition, the yields of these 10 kinds of acetals/ketals are 47.3∼94.2%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1COA of Formula: C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.COA of Formula: C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of 2-methyl-2-ethoxycarbonylmethyl-1,3-dioxolane with H₄SiW₆Mo₆O₄₀/SiO₂ was written by Wu, Mei;Ye, Ming-yan;Duan, Yun-li;Yu, Li;Lu, Bao-lan;Yang, Shui-jin. And the article was included in Jingxi Yu Zhuanyong Huaxuepin in 2012.Synthetic Route of C8H14O4 The following contents are mentioned in the article:

A novel catalyst, H₄SiW₆Mo₆O₄₀/SiO₂ was synthesized by a sol-gel technique, and characterized by FTIR and XRD. 2-Methyl-2-ethoxycarbonylemethyl-1, 3-dioxolane was synthesized from Et acetoacetate and ethylene glycol in the presence of H₄SiW₆Mo₆O₄₀/SiO₂ as catalyst. The factors influencing the synthesis were discussed and the best reaction conditions were found out. Exptl. results showed that H₄SiW₆Mo₆O₄₀/SiO₂ is an excellent catalyst. Under the exptl. conditions as follows: molar ratio of Et acetoacetate to ethylene glycol is 1:1.5, the mass ratio of the catalyst is 1.0% of all the reactants, volume of cyclohexane is 8 mL, and the reaction time is 60 min, the yield of 2-methyl-2-ethoxycarbonylmethyl-1, 3-dioxolane can reach 72.8%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Synthetic Route of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Synthetic Route of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem