Category: Dioxole

Synthesis and application of poly(diallyldimethylammonium tribromide) as a novel polymeric brominating agent was written by Hossein, Mahdavi;Zahra, Kachoei. And the article was included in Chinese Journal of Chemistry in 2010.Product Details of 3418-21-1 This article mentions the following:

In this study, the synthesis and applications of a new supported tribromide reagent is reported. This supported tribromide is used in α-bromoacetalization of ketones, bromination of alkenes and regioselective bromination of activated aromatic compounds This method is mild and no Br₂ and HBr were used. Other advantages of this reagent are stability, high efficiency, simple filterability and reusability. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Product Details of 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Product Details of 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis and structural characterization of lower rim halogenated pyrogallol[4]arenes: bi-layers and hexameric nano-capsules was written by Dalgarno, Scott J.;Power, Nicholas P.;Antesberger, Jochen;McKinlay, Robert M.;Atwood, Jerry L.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2006.Application In Synthesis of 2-(4-Chlorobutyl)-1,3-dioxolane This article mentions the following:

Two lower rim halogenated pyrogallol[4]arenes have been synthesized and structurally characterized as either bi-layer or hexameric nano-capsule motifs depending upon chain length and functionalization. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Application In Synthesis of 2-(4-Chlorobutyl)-1,3-dioxolane).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Application In Synthesis of 2-(4-Chlorobutyl)-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

A study of deketalization of rigid β-aminoketones was written by Kim, Jack C.;Lee, Yong Tae;Yoon, Ung Chan;Cho, In Seop;Moon, Sung Hwan;Han, Sun Hong. And the article was included in Taehan Hwahakhoe Chi in 1988.SDS of cas: 3418-21-1 This article mentions the following:

The causes of failure in the deketalization of rigid β-aminoketals were sep. investigated by examining the deketalization of ketals I (R = NH₂, N⁺Me₃, NHAc), and by examining the deketalization of non-rigid β-aminoketal 2-amino-1-ethylenedioxyacetophenone (II) and non-rigid aliphatic acetals R¹CH(OMe)₂ (III, R¹ = NMe₂, CH₂NH₂). While I (R = NH₂, N⁺Me₃) were not hydrolyzed in the various acidic conditions, I (R = NHAc) was easily deketalized. These results indicate the importance of electrostatic repulsion in the dicationic intermediates as a factor in the failure of deketalization. The easy deketalization of compounds II and III indicate that the structural characters of rigid β-aminoketals are also important factors in the hydrolysis of β-aminoketals. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1SDS of cas: 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.SDS of cas: 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

One-pot α-bromoacetalization of carbonyl compounds was written by Visweswariah, Sandhya;Prakash, G.;Bhushan, Vidya;Chandrasekaran, S.. And the article was included in Synthesis in 1982.Safety of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

Alkanones and cycloalkanones were treated with HOCH₂CH₂OH and PhN⁺Me₃ Br₃^– to yield α-bromo ketone ethylene ketals. Thus, PhN⁺Me₃ Br₃^– was added to Me₂CO, HOCH₂CH₂OH, and THF, and the mixture was stirred ≥ 20 h at room temperature to give bromoacetone ethylene ketal. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Safety of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Safety of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Polymer supported arene-catalyzed lithiation reactions was written by Gomez, Cecilia;Ruiz, Sonia;Yus, Miguel. And the article was included in Tetrahedron in 1999.Application In Synthesis of 2-(4-Chlorobutyl)-1,3-dioxolane This article mentions the following:

The reaction of functionalized chlorinated materials with an excess of lithium and a catalytic amount of a naphthalene (P_N) or biphenyl (P_B) supported polymer (easily prepared by radical copolymerization of 2-vinylnaphthalene or 4-vinylbiphenyl with vinylbenzene and divinylbenzene) in THF and electrophiles [Me₃SiCl, ⁱPrCHO, PhCHO, Et₂CO, (CH₂)₄CO, (CH₂)₅CO, (c-C₃H₅)₂CO, iPr₂CO, PhCOMe, PhCH=NPh] at -78 or -50°C leads, after hydrolysis with water, to the expected functionalized products. Such polymeric reagents were 2-ethenylnaphthalene polymer with ethenylbenzene and diethenylbenzene and 4-ethenyl-1,1′-biphenyl polymer with ethenylbenzene and diethenylbenzene. The polymeric catalyst is quant. recovered and can reused several times without any loss of activity. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Application In Synthesis of 2-(4-Chlorobutyl)-1,3-dioxolane).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Application In Synthesis of 2-(4-Chlorobutyl)-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Facile synthesis of enol ethers by cleavage of α-bromoacetals and α-bromoketals mediated by SmI₂ was written by Park, H. S.;Kim, S. H.;Park, M. Y.;Kim, Y. H.. And the article was included in Tetrahedron Letters in 2001.Synthetic Route of C10H11BrO2 This article mentions the following:

Cyclic α-bromo acetals, cyclic α-bromo ketals and cyclic α-bromo thioketals, derived from cyclic and acyclic ketones and aldehydes, reacted with samarium diiodide at -78° in THF to furnish enol ethers or thioenol ethers containing hydroxy or thiol moieties in high yields. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Synthetic Route of C10H11BrO2).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Synthetic Route of C10H11BrO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis and screening of a new group of fungicides: 1-(2-phenyl-1,3-dioxolan-2-ylmethyl)-1,2,4-triazoles was written by Van Gestel, Jef;Heeres, Jan;Janssen, Marcel;Van Reet, Gustaaf. And the article was included in Pesticide Science in 1980.Application of 3418-21-1 This article mentions the following:

The title triazole fungicides prepared by condensation of substituted phenacyl bromides with vicinal diols, and subsequent treatment of the resulting bromoketals with Na 1,2,4-triazole, were screened for activity against 7 species. E.g., I [71500-05-5] was effective in controlling powdery mildew and barley and in controlling bean rust; it was also systemically active. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Application of 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Application of 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Arene-catalyzed lithiation reactions with lithium at low temperature was written by Yus, Miguel;Ramon, Diego J.. And the article was included in Journal of the Chemical Society, Chemical Communications in 1991.Name: 2-(4-Chlorobutyl)-1,3-dioxolane This article mentions the following:

The reaction of functionalized alkyl chlorides or Ph sulfides with an excess of lithium powder in the presence of a catalytic amount of an arene (1%; naphthalene, biphenyl, 4,4′-di-tert-butylbiphenyl) in THF at -78° gives the corresponding organolithium compounds, which react with electrophiles such as water, isobutyraldehyde, or cyclohexanone to yield the expected reaction products. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Name: 2-(4-Chlorobutyl)-1,3-dioxolane).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Name: 2-(4-Chlorobutyl)-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Intramolecular 1,6-hydride transfer in acyclic 1,6-diols: a mechanistic study was written by Gil, Juan F.;Ramon, Diego J.;Yus, Miguel. And the article was included in Tetrahedron in 1994.Product Details of 118336-86-0 This article mentions the following:

The reaction of acyclic 1,6-diol I with 85% phosphoric acid at toluene reflux ketone II through an intramol. 1,6-hydride transfer. This fact is proven by using a deuterated 1,6-diol, in which the corresponding 1,6-deuteride transfer occurs. A mechanistic proposal through a protonated oxepane is formulated, which implies an actual 1,3-hydride transfer; this mechanism differs from the reported one in the literature for cyclic 1,6-diols, in which a real 1,6-hydride transfer takes place due to a proximity effect. In the experiment, the researchers used many compounds, for example, 2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0Product Details of 118336-86-0).

2-(4-Chlorobutyl)-1,3-dioxolane (cas: 118336-86-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Product Details of 118336-86-0

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Cyclopentyl methyl ether-NH₄X: a novel solvent/catalyst system for low impact acetalization reactions was written by Azzena, Ugo;Carraro, Massimo;Mamuye, Ashenafi Damtew;Murgia, Irene;Pisano, Luisa;Zedde, Giuseppe. And the article was included in Green Chemistry in 2015.Synthetic Route of C10H11BrO2 This article mentions the following:

Cyclopentyl Me ether, a low impact ether forming a pos. azeotrope with water, was successfully employed as a solvent in the synthesis of 1,3-dioxanes and 1,3-dioxolanes carried out under Dean-Stark conditions by the acetalization of aliphatic and aromatic aldehydes or ketones, employing ammonium salts as environmentally friendly acidic catalysts. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Synthetic Route of C10H11BrO2).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C10H11BrO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem