Brief introduction of 7524-52-9

There is still a lot of research devoted to this compound(SMILES:N[C@@H](CC1=CNC2=CC=CC=C12)C(OC)=O.[H]Cl)Reference of H-Trp-OMe.HCl, and with the development of science, more effects of this compound(7524-52-9) can be discovered.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Copper-promoted N-arylation of the indole side chain of tryptophan using triarylbismuthines, published in 2020-09-07, which mentions a compound: 7524-52-9, Name is H-Trp-OMe.HCl, Molecular C12H15ClN2O2, Reference of H-Trp-OMe.HCl.

A simple protocol for the regioselective N-arylation of the indole side chain of tryptophan using triarylbismuth reagents as the arylating agent is reported. The reaction is catalyzed by copper(II) acetate, and operates in the presence of triethylamine or pyridine under air at 50°C. This reaction allows the transfer of aryl groups bearing electron neutral, donating or withdrawing substituents at any position of the ring, shows high functional group tolerance, and retains the integrity of the stereogenic center. The protocol was utilized to N-arylate tryptophan-containing di- and tripeptides.

There is still a lot of research devoted to this compound(SMILES:N[C@@H](CC1=CNC2=CC=CC=C12)C(OC)=O.[H]Cl)Reference of H-Trp-OMe.HCl, and with the development of science, more effects of this compound(7524-52-9) can be discovered.

Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem