The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine( cas:1265884-98-7 ) is researched.Application In Synthesis of 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine.Deng, Jun; Zhou, Shupeng; Zhang, Wenhao; Li, Jian; Li, Ruofan; Li, Ang published the article 《Total Synthesis of Taiwaniadducts B, C, and D》 about this compound( cas:1265884-98-7 ) in Journal of the American Chemical Society. Keywords: enantioselective synthesis taiwaniadduct B C D; iridium catalyzed asym polyene cyclization taiwaniadduct synthesis; erbium catalyzed Diels Alder taiwaniadduct synthesis; carbonyl ene cyclization taiwaniadduct synthesis. Let’s learn more about this compound (cas:1265884-98-7).
The first total syntheses of taiwaniadducts B, C, and D have been accomplished. Two diterpenoid segments [trans-ozic Me ester (I) and II] were prepared with high enantiopurity, both through Ir-catalyzed asym. polyene cyclization. A sterically demanding I + II intermol. Diels-Alder reaction promoted by Er(fod)3 assembled the scaffold of taiwaniadducts B and C. A carbonyl-ene cyclization forged the cage motif of taiwaniadduct D at a late stage, providing over 200 mg of this compound
Compound(1265884-98-7)Application In Synthesis of 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine), if you are interested, you can check out my other related articles.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem