Day: November 22, 2022

Catalytic synthesis of 2-methyl-2-ethyl acetoacetate-1,3-dioxolane with iodine was written by Yang, Shuijin;Tong, Wenlong. And the article was included in Jingxi Shiyou Huagong Jinzhan in 2008.Reference of 6413-10-1 The following contents are mentioned in the article:

In this paper, 2-methyl-2-Et acetoacetate-1, 3-dioxolane was synthesized from Et acetoacetate and ethylene glycol using I₂ as catalyst. The effects of molar ratio of Et acetoacetate to ethylene, the catalyst dosage and reaction time on the yield of 2-methyl-2-Et acetoacetate-1,3-dioxolane were investigated. Comparison of catalytic activity of different catalysts was made. Exptl. result showed that yield of 2-methyl-2-Et acetoacetate-1,3-dioxolane could reach 73.2 % under the conditions as follows: molar ratio of Et acetoacetate to ethylene 1:1.8, the dosage of catalyst 0.3 % based on feed stocks, cyclohexane as carrying-water reagent, and the reaction time 1.0 h. The catalyst had a fairly high catalytic activity for the ketalization reaction, and had the characteristics in short reaction time, less catalyst dosage and high yield. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Reference of 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Reference of 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Studies on catalytic synthesis of fructone with modified fly ash was written by Liu, Xianxiang;Yin, Dulin;Yang, Yongjun;Zuo, Chuanpeng;Wang, Jihui. And the article was included in Riyong Huaxuepin Kexue in 2009.Category: dioxole The following contents are mentioned in the article:

The synthesis of fructone from Et acetoacetate and ethylene glycol using fly ash modified by ammonium persulfate as solid acid catalyst was investigated. Various reaction parameters such as reaction time, ratio of Et acetoacetate to ethylene glycol, catalyst amount and water-carrying reagent amount were studied. The optimum reaction conditions were as follows: the molar ratio of Et acetoacetate to ethylene glycol 1:1.8, the quantity of catalyst 1.5 weight% by weight of Et acetoacetate, amount of cyclohexane 15 mL, and the reaction time 3 h. Under this optimum condition, the yield of fructone reaches 95.9%. The exptl. results showed that fly ash modified by ammonium persulfate was an excellent catalyst for synthesis of fructone. Compared with other acid catalysts, the sulfonated activated carbon has higher activity, less used quantity and reusability. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Category: dioxole).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Hetaryl derivatives of 7-deazapurine ribonucleosides: potent cytostatic agents was written by Perlikova, Pavla;Naus, Petr;Bourderioux, Aurelie;Hocek, Michal. And the article was included in Collection Symposium Series in 2011.Application In Synthesis of ((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol The following contents are mentioned in the article:

A symposium. A series of novel 7-deazapurine ribonucleosides substituted with aryl and hetaryl groups has been prepared Suzuki or Stille cross-coupling reactions with 6-chloro-7-deazapurine ribonucleosides substituted with H, F of Cl atom in position 7 were used in the key step of the synthesis. Either cross-coupling of protected ribonucleoside with appropriate (het)aryl-boronic acid or stannane followed by deprotection, or single-step aqueous-phase Suzuki cross-coupling reaction of unprotected 7-deazapurine ribonucleoside with boronic acid provided target (het)aryl-7-deazapurine ribonucleosides. 6-Furyl- and 6-thienyl-7-deazapurine ribonucleosides showed cytostatic effect in multiple cancer cell lines in nano-molar range. Application of cyclosaligenyl and alanyl-ester phosphoramidate prodrugs did not improved cytostatic activity of parent nucleosides. This study involved multiple reactions and reactants, such as ((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol (cas: 158078-04-7Application In Synthesis of ((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol).

((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol (cas: 158078-04-7) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Application In Synthesis of ((3aR,4R,6R,6aR)-6-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Studies on catalytic synthesis of fructone by L-proline ionic liquid was written by Liu, Wenmin;Ding, Chenghua;Xing, Wenru;Shi, Xuejun;Liu, Yang. And the article was included in Nanyang Shifan Xueyuan Xuebao in 2010.Recommanded Product: 6413-10-1 The following contents are mentioned in the article:

The synthesis of fructone from Et acetoacetate and ethylene glycol using L-proline ionic liquid as catalyst was investigated. Various reaction parameters such as ratio of Et acetoacetate to ethylene glycol, catalyst amount, the catalyst dosage, the effects of the sort of water-carrying agent and the water-carrying agent amount and reaction time on the product yield were investigated in details. The exptl. results indicated that the molar ratio of Et acetoacetate to ethylene glycol was 1.0:1.4, the quantity of catalyst was equal to 2.0 g/mol Et acetoacetate, amount of cyclohexane was 40 mL, and the reaction time was 3.5 h. The yield of fructone reached 88.9% under the optimum condition. The isolation of the desired products could be achieved via simple separation and ionic liquids could be reused. The catalytic activity was not decreased obviously after recycling for 4 times. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Recommanded Product: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Recommanded Product: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Modeling ready biodegradability of fragrance materials was written by Ceriani, Lidia;Papa, Ester;Kovarich, Simona;Boethling, Robert;Gramatica, Paola. And the article was included in Environmental Toxicology and Chemistry in 2015.Related Products of 6413-10-1 The following contents are mentioned in the article:

Here, quant. structure activity relations were developed for predicting ready biodegradability of ∼200 heterogeneous fragrance materials. Two classification methods, classification and regression tree (CART) and k-nearest neighbors (kNN), were applied to perform the modeling. The models were validated with multiple external prediction sets, and the structural applicability domain was verified by the leverage approach. The best models had good sensitivity (internal ≥80%; external ≥68%), specificity (internal ≥80%; external 73%), and overall accuracy (≥75%). Results from the comparison with BIOWIN global models, based on group contribution method, show that specific models developed in this study perform better in prediction than BIOWIN6, in particular for the correct classification of not readily biodegradable fragrance materials. Environ Toxicol Chem 2015;9999:1-8. © 2015 SETAC. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Related Products of 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Related Products of 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis technology of fructone was written by Wang, Qing-ning;Zhang, Lei;Fang, Ming-feng;Jiang, Rui-yu. And the article was included in Riyong Huaxue Gongye in 2008.HPLC of Formula: 6413-10-1 The following contents are mentioned in the article:

Using acid-treated attapulgite clay as supporter, attapulgite clay supported phosphotungstic acid catalyst were prepared through impregnation method, and characterized by XRD, IR and UV spectrophotometry. Such catalyst was used for synthesis of fructone. Effects of molar ratio of Et acetoacetate to glycol, the dosage of catalyst, the dosage of water stripping agent, the reaction time, the reaction temperature on the esterification yield were investigated. The exptl. results showed that attapulgite clay supported phosphotungstic acid catalyst has good catalytic activity, structural stability, and can be reused. Optimum conditions for the synthesis are; molar ratio of Et acetoacetate to glycol is 1.0 = 1.5; the dosage of catalyst is 2 g; the amount of benzene as water stripping agent is 50 mL; the reaction time is 3 h; the reaction temperature is 110°. Its yield achieves higher than 89.7%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1HPLC of Formula: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.HPLC of Formula: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of 2-methyl-2-ethoxycarbonylmethyl-1,3-dioxolane with H₄SiW₆Mo₆O₄₀/SiO₂ was written by Wu, Mei;Ye, Ming-yan;Duan, Yun-li;Yu, Li;Lu, Bao-lan;Yang, Shui-jin. And the article was included in Jingxi Yu Zhuanyong Huaxuepin in 2012.Synthetic Route of C8H14O4 The following contents are mentioned in the article:

A novel catalyst, H₄SiW₆Mo₆O₄₀/SiO₂ was synthesized by a sol-gel technique, and characterized by FTIR and XRD. 2-Methyl-2-ethoxycarbonylemethyl-1, 3-dioxolane was synthesized from Et acetoacetate and ethylene glycol in the presence of H₄SiW₆Mo₆O₄₀/SiO₂ as catalyst. The factors influencing the synthesis were discussed and the best reaction conditions were found out. Exptl. results showed that H₄SiW₆Mo₆O₄₀/SiO₂ is an excellent catalyst. Under the exptl. conditions as follows: molar ratio of Et acetoacetate to ethylene glycol is 1:1.5, the mass ratio of the catalyst is 1.0% of all the reactants, volume of cyclohexane is 8 mL, and the reaction time is 60 min, the yield of 2-methyl-2-ethoxycarbonylmethyl-1, 3-dioxolane can reach 72.8%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Synthetic Route of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Synthetic Route of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of acetals and ketals with I₂/PAn was written by Yang, Shuijin;Tong, Wenlong;Yin, Guojun. And the article was included in Beijing Keji Daxue Xuebao in 2006.COA of Formula: C8H14O4 The following contents are mentioned in the article:

A new environmental friendly catalyst, I₂/Pan, was prepared The catalytic activities of I₂/PAn in synthesizing 2-methyl-2-ethoxycarbonylmethyl-1, 3-dioxolane, 2, 4-dimethyl-2-ethoxycarbonylmethyl-1, 3-dioxolane, cyclohexanone ethylene ketal, cyclohexanone 1,2-propanediol ketal, butanone ethylene ketal, butanone 1, 2-propanediol ketal, 2-phenyl-1, 3-dioxolane, 4-methyl-2-phenyl-1, 3-dioxolane, 2-propyl-1, 3-dioxolane, and 4-methyl-2-propyl-1, 3-dioxolane were reported. It is demonstrated that I₂/PAn is an excellent catalyst. Various factors concerned in these reactions were investigated. An optimum condition was found, i.e., the molar ratio of aldehyde/ketone to glycol is 1/1.6, the mass ratio of the catalyst used to the reactants is 0.2%, and the reaction time is 1.0 h. Under the optimum condition, the yields of these 10 kinds of acetals/ketals are 47.3∼94.2%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1COA of Formula: C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.COA of Formula: C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of heterogeneous mesoporous silica-supported 12-tungstophosphoric acid catalyst and its catalytic performance was written by Guo, Hong-qi;Mao, Ming-fu;Ni, Zhong-bin;Chen, Ming-qing;Liu, Shi-rong. And the article was included in Fenzi Cuihua in 2011.Synthetic Route of C8H14O4 The following contents are mentioned in the article:

12-Tungstophosphoric acid was supported on SBA-15 and amine-modified SBA-15 by impregnation. The structure and properties of the catalyst were characterized by FT-IR spectroscopy, X-ray diffraction, N₂ adsorption-desorption, TEM, Raman spectra and NH₃-TPD technol. The result confirmed the mesostructure for SBA-15 and the Keggin structure of the heteropolyanions was preserved. However, aggregation occurred in the high loading, and because of the pore blockage, the BET surface area, pore volume and pore diameter decreased obviously. The tungstophosphoric acid can disperse in the pore of the support SBA-15/NH₂, but the acidity of the catalyst reduced. The catalytic activities of the catalysts were evaluated for the esterification reaction of Et acetoacetate and ethylene glycol and the catalysts supported on amine-modified SBA-15 show excellent reusability and selectivity. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Synthetic Route of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of SO^2-₄/TiO₂-La₂O₃ solid superacid and its catalytic activities in acetalation and ketalation was written by Yang, Shui-jin;Bai, Ai-min;Sun, Ju-tang. And the article was included in Journal of Zhejiang University, Science, B in 2006.SDS of cas: 6413-10-1 The following contents are mentioned in the article:

SO^2-₄/TiO₂-La₂O₃, a novel solid superacid, was prepared and its catalytic activities at different synthetic conditions are discussed with esterification of n-butanoic acid and Bu alc. as probing reaction. The optimum conditions have also been found, mole ratio of n(La³⁺):n(Ti⁴⁺) is 1:34, the soaked consistency of H₂SO₄ is 0.8 mol/L, the soaked time of H₂SO₄ is 24 h, the calcining temperature is 480 °C, the calcining time is 3 h. Then it was applied in the catalytic synthesis often important ketals and acetals as catalyst and revealed high catalytic activity. Under these conditions on which the molar ratio of aldehyde/ketone to glycol is 1:1.5, the mass ratio of the catalyst used in the reactants is 0.5%, and the reaction time is 1.0 h, the yields of ketals and acetals can reach 41.4%∼95.8%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1SDS of cas: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.SDS of cas: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem