Day: November 21, 2022

Fasi, Andras published the artcileIsomerization and Dimerization Reactions of Methyloxirane over Various Types of Zeolite and Zeotype, Application In Synthesis of 1193-11-9, the publication is Journal of Catalysis (2001), 200(2), 340-344, database is CAplus.

The ring-opening reactions of methyloxirane on various zeolites and zeotypes (HZSM-5, CuZSM-5, HY, AlMCM-41, SiMCM-41, and BMCM-41) were investigated at 363 K either in a pulse reactor or in a circulation system, in the presence of hydrogen or nitrogen. The acidic mol. sieves were found to be active in isomerization (the products are propionaldehyde and acetone) and dimerization (the products are dioxolane and dioxane derivatives) reactions. Deoxygenation was of minor importance in hydrogen or nitrogen atm. The major product formation pathway was dimerization on every catalytically active material. This transformation route was favored by the confined environment. (c) 2001 Academic Press.

Journal of Catalysis published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Application In Synthesis of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Gendrineau, Thomas published the artcileRoom-Temperature Rhodium-Catalyzed Asymmetric 1,4-Addition of Potassium Trifluoro(organo)borates, COA of Formula: C38H24F4O4P2, the publication is Organic Letters (2009), 11(15), 3486-3489, database is CAplus and MEDLINE.

For the first time, the room-temperature rhodium-catalyzed asym. 1,4-addition of potassium aryltrifluoroborates to α,β-unsaturated substrates is described. Thanks to the use of a chiral diene as ligand for rhodium and triethylamine as base, to facilitate transmetalation of the boron species, high yields and enantioselectivities were generally achieved. Moreover, the use of such tetravalent boron species offers some improvements compared to the use of boronic acids in term of stability and ease of purification

Organic Letters published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, COA of Formula: C38H24F4O4P2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kamaraj, Chinnaperumal published the artcileNovel and environmental friendly approach; Impact of Neem (Azadirachta indica) gum nano formulation (NGNF) on Helicoverpa armigera (Hub.) and Spodoptera litura (Fab.), Category: dioxole, the publication is International Journal of Biological Macromolecules (2018), 107(Part_A), 59-69, database is CAplus and MEDLINE.

The future of this study was to prepare a natural pesticide which will not harm the environment and yet control pests. Neem gum nano formulation (NGNF), a novel biopesticide prepared from the Neem gum extract (Azadirachta indica) (NGE) was evaluated for its antifeedant, larvicidal and pupicidal activities against Helicoverpa armigera (Hub.) and Spodoptera litura (Fab.) at 100 ppm. The NGNF showed significant (100%) antifeedant, larvicidal and pupicidal activities against H. armigera and S. litura. The LC₅₀ values of 10.20, 12.49 and LC₉₀ values of 32.68, 36.68 ppm on H. armigera and S. litura, resp. at 100 ppm. The NGNF treatments showed differences in the activities of detoxifying enzymes, carboxylesterases, glucosidases and glutathione S-transferases in the larval gut. Earthworm toxicity illustrated that 6.25 ppm of chem. insecticides (cypermethrin) varied widely in their contact toxicities compared to 100 ppm of NGNF and control in both contact filter paper and artificial soil test. The NGNF were characterized and confirmed by FTIR, XRD, SEM and EDX anal. Ten compounds were identified from the Neem gum extract (NGE) by Gas Chromatog.-Mass Spectrometry (GC-MS) anal. The major compounds were fatty acids like Hexadecanoic acid, oleic acid, and ricinoleic acid. NGNF could be used as an agent to prepare novel bio-pesticides formulations.

International Journal of Biological Macromolecules published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Espinosa, A. published the artcileOxocarbonium ions: deketalization of 1,3-dioxolanes and other processes in nonaqueous media, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Anales de Quimica (1991), 87(3), 391-5, database is CAplus.

Alcoholysis of [(hydroxypropoxy)ethyl]dioxolane I (R = Me) resulted in deketalization to give alkoxybutanones R¹OCH₂CH₂COMe (R¹ = C₁-C₃ alkyl). The deketalization indicates that the oxocarbonium ion intermediates undergo an oxirane elimination. The effect of alc. solvating power on exchange product yields was studied using I (R = H, Me). A linear relation was found for transetherification, transacetalization, and transacetalization-cyclization.

Anales de Quimica published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Liu, Taotao published the artcileZeolite nanofiber assemblies as acid catalysts with high activity for the acetalization of carbonyl compounds with alcohols, Category: dioxole, the publication is RSC Advances (2014), 4(35), 18217-18221, database is CAplus.

Zeolite nanofiber assemblies (HNB-MOR) as efficient heterogeneous catalysts for the formation of a range of acetals in good yields. The mesoporosity of HNB-MOR benefits mass transfer, and the strong acidic sites on HNB-MOR facilitate acetalization activity. The catalyst can be reused 10 times without loss of activity.

RSC Advances published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Shan, Gang published the artcileC-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Angewandte Chemie, International Edition (2018), 57(43), 14250-14254, database is CAplus and MEDLINE.

In the presence of a nonracemic cyclopentenopyridine rhodium complex, O-(arylpentynyl) arylhydroxamates such as I underwent enantioselective C-H activation and cyclization reactions mediated by dibenzoyl peroxide and CsOAc in 2-chloroethanol/1,2-dichloroethane to yield atropisomeric arylisoquinolinones such as II in 45-95% yields and in 78:22-96:4 er. Five of the arylisoquinolinone products (including II) inhibited the Hedgehog pathway in human cells; one of the compounds tested inhibited the Hedgehog pathway but did not displace labeled cyclopamine from Smoothened, implying that at least one of the arylisoquinolinones does not inhibit the Hedgehog pathway through binding to Smoothened.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C18H34N4O5S, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Rigo, Davide published the artcileAcid-Catalyzed Reactions of Isopropenyl Esters and Renewable Diols: A 100% Carbon Efficient Transesterification/Acetalization Tandem Sequence, from Batch to Continuous Flow, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is ACS Sustainable Chemistry & Engineering (2019), 7(23), 18810-18818, database is CAplus.

A new acid-catalyzed tandem sequence was investigated for the upgrading of renewable 1,2-diols such as propylene glycol (PG) and ethylene glycol (EG), with isopropenyl esters. For example, at 50 °C and in the presence of Amberlyst-15, the reaction of PG with nontoxic isopropenyl acetate allowed an initial irreversible monotransesterification of the diol, releasing acetone which then promoted acetalization on a second mol. of the glycol. The overall protocol was 100% carbon efficient, affording water as the sole byproduct. The reaction scope was extended to higher homologs of enol esters as isopropenyl-octanoate and phenylbutyrate. Addnl., the tandem sequence was successfully transferred in the continuous-flow (CF) mode where the catalyst (Amberlyst-15) could be used virtually indefinitely without loss of performance, and the solvent (THF or CPME) was quant. recovered and reused. Under CF conditions, the reaction of PG with isopropenyl acetate could be run at 30 °C and atm. pressure with a (nonoptimized) productivity up to 9.7 mmol g_cat^-1 h^-1, 3 times higher than that achieved in the batch mode. When ethylene glycol was used, a lower tandem selectivity was observed due to predominance of transesterification products, mono- and diesters, over the acetal compound A 100% carbon efficient upgrading of renewable 1,2-diols through tandem monotransesterification and acetalization reactions mediated by isopropenyl esters is presented.

ACS Sustainable Chemistry & Engineering published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Yuan, Zhenbo published the artcilePalladium-Catalyzed Asymmetric Intramolecular Reductive Heck Desymmetrization of Cyclopentenes: Access to Chiral Bicyclo[3.2.1]octanes, Application In Synthesis of 503538-69-0, the publication is Angewandte Chemie, International Edition (2019), 58(9), 2884-2888, database is CAplus and MEDLINE.

A palladium-catalyzed asym. reductive Heck reaction of unactivated aliphatic alkenes, with eliminable β-hydrogen atoms, was realized for the first time. A series of optically active bicyclo[3.2.1]octanes bearing chiral quaternary and tertiary carbon stereocenters were obtained in good yields with excellent enantioselectivities, exhibited good functional-group tolerance and scalability. Moreover, deuterated optically active bicyclo[3.2.1]octanes were also obtained in high efficiency.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C9H10O4, Application In Synthesis of 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Lu, Ting published the artcileFour Strandberg-type polyoxometalates with organophosphine centre decorated by transition metal-2,2′-bipy/H₂O complexes, Recommanded Product: 1,4-Dioxaspiro[4.5]decane, the publication is Journal of Solid State Chemistry (2017), 52-57, database is CAplus.

Four inorganic-organic hybrid compounds composed of Strandberg-type organophosphomolybdate anion [(C₆H₅PO₃)₂Mo₅O₁₅]^4- (abbreviated as (PhP)₂Mo₅) and transition metal (TM)-2,2′-bipy/H₂O complex units, namely [(TM(H₂O)(bipy))₂(C₆H₅PO₃)₂Mo₅O₁₅]_n (TM = Co, (1); Ni, (2)), [(Cu(bipy)₂)₂(C₆H₅PO₃)₂Mo₅O₁₅]·2H₂O (3) and [(Zn(bipy)(μ-OH))₂(Zn(bipy)₂(C₆H₅PO₃)₂Mo₅O₁₅)₂]·3H₂O (4) (bipy = 2,2′-bipyridine), were successfully constructed under hydrothermal conditions, and their structures were determined by single crystal x-ray diffraction anal. and spectroscopic methods. The central heteroatoms in these polyoxometalates (POMs) are all organophosphine (RP) groups. Compound 1 and compound 2 are isostructural (PhP)₂Mo₅-based TM-coordination polymers with the two-dimensional layer frameworks. In compound 3, the bi-supporting structure containing one (PhP)₂Mo₅ unit and two [Cu(bipy)₂]²⁺ cations. For compound 4, it can be regarded as a dimer of two bi-supporting {Zn(bipy)₂(PhP)₂Mo₅Zn(bipy)} clusters that were connected by two μ-OH groups. The acid-catalytic activities and fluorescence properties of the four hybrids have been investigated.

Journal of Solid State Chemistry published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Recommanded Product: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Likhterov, V. R. published the artcile1,3-Dioxolanes. I. Chlorination of some cyclic ketals of acetone and vicinal glycols, Product Details of C6H12O2, the publication is Zhurnal Organicheskoi Khimii (1968), 4(1), 69-72, database is CAplus.

Chlorination of 2,2,4-trimethyl-1,3-dioxolane (I), 2,2-dimethyl-4-chloromethyl-1,3-dioxolane, 2,2-dimethyl-4-methoxymethyl-1,3-dioxolane, 2,2-dimethyl-4-acetoxymethyl-1,3-dioxolane (II), and 2,2-dimethyl-1,3-dioxolane is described. The exothermic reaction was carried out with cooling at 15-20° by passing Cl through the dioxolane followed by distillation The starting dioxolanes were all known previously with the exception of II, b2 71-2°. Chlorination gave 2-chloromethyl-2-methyl-4-(R-substituted)-1,3-dioxolanes (III) (R, % yield, b.p./mm., and n20D given): Me, 73.5, 53-4°/15, 1.4352; CH2Cl, 78.3, 71-2°/2, 1.4701; MeOCH2, 71.3, 69-71°/2, 1.4486; MeCO2CH2, 72.0, 103-5°/2, 1.4535; H, 76.0, 60-3°/20, 1.4450. Alk. hydrolysis of III (R = MeCO2CH2) gave III (R = CH2OH), b3 96-8°, n20D 1.4688 (containing 46-50% cis- and 50-4% trans-isomer). Reaction of III (R = CH2Cl) with MeCO2K gave III (R = MeCO2CH2). Action of PCl5 on III (R = CH2OH) gave III (R = CH2Cl). Hydrolysis of III gave MeCOCH2Cl, identified by the m.p. of its 2,4-dinitrophenylhydrazone derivative

Zhurnal Organicheskoi Khimii published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Product Details of C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem