On January 31, 1997, Zhu, Bao Hua; Liu, Ze Hua; Yan, Hong; Liu, Jun; Chen, Huilan published an article.Computed Properties of 38838-06-1 The title of the article was The coenzyme B12 analogs-ribosylcobalamins: synthesis, characterization, and photolysis studies. And the article contained the following:
Two analogs of Coenzyme B12, i.e., 1-methyl-5-deoxy-β-D(-)ribofuranos-5-ylcobalamin (RibCbl) and 1-methyl-5-deoxy-2,3-isopropylidene-β-D(-)-ribofuranos-5-yl-cobalamin(RibCbl*), were synthesized. They were characterized by UV-vis and 2D 1H NMR spectroscopies. Furthermore, aerobic and anaerobic photolysis of the two compounds have been studied. Kinetic data of anaerobic photoinduced homolysis for two ribosylcobalamin(AdoCbl) have been determined The half-times under the same exptl. conditions are: RibCbl*, t1/2 = 488 min; RibCbl, t1/2 = 122 min; and AdoCbl, t1/2 = 3 min, resp. Therefore, both of ribosylcobalamins are less photosensitive than Coenzyme B12. These results are discussed in terms of the in-cage chem. process as well as steric and electronic effects of the axial ligand on the Co-C bond homolysis. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Computed Properties of 38838-06-1
The Article related to steric effect bond homolysis methyldeoxyribofuranosylcobalamin preparation, methyldeoxyribofuranosylcobalamin aerobic anaerobic photolysis kinetics, coenzyme b12 analog ribosylcobalamin preparation photolysis and other aspects.Computed Properties of 38838-06-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem