One-step for the preparation of α-haloacetal of ketones with N-bromosuccinimide/N-chlorosuccinimide (NBS/NCS) and ethylene glycol was written by Zheng, Zubiao;Han, Bingbing;Wu, Fang;Shi, Tengfei;Liu, Jie;Zhang, Yong;Hao, Jialong. And the article was included in Tetrahedron in 2016.Formula: C10H11BrO2 This article mentions the following:
A new process that could directly prepare α-haloacetal of ketones from various ketones with N-halosuccinimide (NBS/NCS) and ethylene glycol in one step without any other catalysts is reported. The effects of solvents, NBS/NCS and reaction temperature were studied. Under the optimal condition, most of α-haloacetals of ketones were obtained in 90-100% yield. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Formula: C10H11BrO2).
2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Formula: C10H11BrO2
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem