On August 25, 2020, Zhang, Chen; Zhu, Guozhi; Lu, Yonghua; Gao, Qiu; Liao, Yuting; Li, Yao; Yan, Pangke published a patent.Application of 124038-36-4 The title of the patent was Preparation of 8-hydroxy-1H-quinolin-2-one bridge derivatives as muscarinic receptor M3 antagonists and beta 2-adrenergic receptor agonists. And the patent contained the following:
The invention discloses preparation method of 8-hydroxy-1H-quinolin-2-one bridge ring derivatives, which has the characteristics of diverse structure and high activity. For example, the invention compound I was prepared via multi-step reaction of 4-[[3-[[(7-tertbutoxycarbonyl-3-oxa-7-azabicyclo[3.3.1]nonane-9-yl)oxocarbonylamino]-Ph methyl] phenoxy] methyl] benzoic acid. The invention compounds can be used as muscarinic receptor M3 antagonists and beta 2-adrenergic receptor agonists. The experimental process involved the reaction of Methyl 3-(1,3-dioxolan-2-yl)benzoate(cas: 124038-36-4).Application of 124038-36-4
The Article related to preparation hydroxyquinolinone muscarinic receptor m3 antagonist adrenergic receptor agonist, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Application of 124038-36-4
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem