Catalytic synthesis of 2-methyl-2-ethyl acetoacetate-1,3-dioxolane with iodine was written by Yang, Shuijin;Tong, Wenlong. And the article was included in Jingxi Shiyou Huagong Jinzhan in 2008.Reference of 6413-10-1 The following contents are mentioned in the article:
In this paper, 2-methyl-2-Et acetoacetate-1, 3-dioxolane was synthesized from Et acetoacetate and ethylene glycol using I2 as catalyst. The effects of molar ratio of Et acetoacetate to ethylene, the catalyst dosage and reaction time on the yield of 2-methyl-2-Et acetoacetate-1,3-dioxolane were investigated. Comparison of catalytic activity of different catalysts was made. Exptl. result showed that yield of 2-methyl-2-Et acetoacetate-1,3-dioxolane could reach 73.2 % under the conditions as follows: molar ratio of Et acetoacetate to ethylene 1:1.8, the dosage of catalyst 0.3 % based on feed stocks, cyclohexane as carrying-water reagent, and the reaction time 1.0 h. The catalyst had a fairly high catalytic activity for the ketalization reaction, and had the characteristics in short reaction time, less catalyst dosage and high yield. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Reference of 6413-10-1).
Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Reference of 6413-10-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem