On February 12, 2010, Yadav, J. S.; Reddy, P. Narayana; Reddy, B. V. Subba published an article.COA of Formula: C9H15IO4 The title of the article was Stereoselective total synthesis of (-)-ovalicin. And the article contained the following:
A new synthetic route for epoxyketone I is described, which is a key intermediate in Barton’s synthesis of ovalicin (II), a powerful anti-angiogenetic inhibitor, from com. available D-ribose. The key reactions involved in this synthesis are ring-closing metathesis, Rubottom oxidation and Corey-Chaykovsky epoxidation The subsequent transformations are carried out according to Barton’s strategy to complete the total synthesis of (-)-ovalicin. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).COA of Formula: C9H15IO4
The Article related to ovalicin stereoselective total synthesis ring closing metathesis, rubottom oxidation stereoselective total synthesis ovalicin, corey chaykovsky epoxidation stereoselective total synthesis ovalicin and other aspects.COA of Formula: C9H15IO4
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem