The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: H-Trp-OMe.HCl(SMILESS: N[C@@H](CC1=CNC2=CC=CC=C12)C(OC)=O.[H]Cl,cas:7524-52-9) is researched.Quality Control of 2-Bromo-6-(bromomethyl)naphthalene. The article 《Visible-light mediated tryptophan modification in oligopeptides employing acylsilanes》 in relation to this compound, is published in Chemistry – A European Journal. Let’s take a look at the latest research on this compound (cas:7524-52-9).
A method for the selective tryptophan modification and labeling of tryptophan-containing peptides is described. Photoirradiation of acylsilanes generates reactive siloxycarbenes which undergo H-N-insertion into the indole moiety of tryptophan to give stable silyl protected hemiaminals. This method is successfully applied to chem. modify various tryptophan containing oligopeptides. The method enables the selective introduction of alkynes to peptides that are eligible for further alkyne-azide click chem. In addition, the dansyl fluorophore can be conjugated to a peptide using this approach.
After consulting a lot of data, we found that this compound(7524-52-9)Synthetic Route of C12H15ClN2O2 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem