What unique challenges do researchers face in 455-70-9

There is still a lot of research devoted to this compound(SMILES：COC(=O)C1=CC(F)=CN=C1)Name: Methyl 5-fluoro-3-pyridinecarboxylate, and with the development of science, more effects of this compound(455-70-9) can be discovered.

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Xing, Bo; Ni, Chuanfa; Hu, Jinbo researched the compound: Methyl 5-fluoro-3-pyridinecarboxylate( cas:455-70-9 ).Name: Methyl 5-fluoro-3-pyridinecarboxylate.They published the article 《Hypervalent Iodine(III) Catalyzed Balz-Schiemann Fluorination under Mild Conditions》 about this compound( cas:455-70-9 ) in Angewandte Chemie, International Edition. Keywords: arenediazonium tetrafluoroborate Balz Schiemann fluorination hypervalent iodine catalyst; fluoride aryl preparation; Balz-Schiemann reaction; aryl fluorides; diazonium salts; fluorination; iodine. We’ll tell you more about this compound (cas:455-70-9).

An unprecedented hypervalent iodine(III)-catalyzed Balz-Schiemann reaction was described. In the presence of a hypervalent iodine compound, the fluorination reaction proceeded under mild conditions (25-60 °C), and featured a wide substrate scope and good functional-group compatibility.

There is still a lot of research devoted to this compound(SMILES：COC(=O)C1=CC(F)=CN=C1)Name: Methyl 5-fluoro-3-pyridinecarboxylate, and with the development of science, more effects of this compound(455-70-9) can be discovered.

Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem