Tag: M.W=300-400

In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system. 57-50-1, Name is Sucrose, SMILES is O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@H]1O[C@@]2(CO)[C@H]([C@@H]([C@@H](CO)O2)O)O, in an article , author is Chang, Hong-Tai, once mentioned of 57-50-1, Application of 57-50-1.

Methyl 2-iodobenzoates 1a-c undergo cyclization reactions with various aromatic aldehydes 2 a-m (RC6H4CHO: R=H 2a, 4-CH3 2b, 4-tBu 2 c, 4-OMe 2 d, 3-OMe 2 e, 4-Cl 2 f, 4-CF3 2g, 4-CN 2h, 4-Ph 2i; benzo[d][1,3]dioxole-5-carbaldehyde (2j), -napthaldehyde (2k), benzofuran-2-carbaldehyde (21), and isonicotinaldehyde (2m)) in the presence of [CoI2(dppe)] (dppe = 1,2-bis(diphenylphosphino)ethane) and Zn powder in dry THF at 75 degrees C for 24 h to give the corresponding phthalide derivatives 3a-m and 3q-t in good to excellent yields. Under similar reaction conditions, less reactive aliphatic aldehydes, heptanal (2n), butyraldehyde (2o), and 2-phenylacetaldehyde (2p) also underwent cyclization reactions with la to provide 3n-p, respectively, in fair to good yields. The catalytic reaction can be further extended to cinnamyl aldehyde (2q) with la to give the corresponding phthalide derivative 3u. This synthetic method is compatible with a variety of functional groups on the aryl ring of 2. The high efficiency of the cobalt catalyst containing a dppe (dppe=1,2-bis(diphenylphosphino)ethane) ligand encouraged us to investigate the asymmetric version of the present catalytic reaction by employing bidentate chiral ligands. Thus, aromatic aldehydes 2a-c, 2f, and 2g undergo cyclization with 2-iodobenzoate (1a) smoothly in the presence of [CoI2(S,S)-dipamp}] ((SS)-dipamp(1S,2S)-(+)-bis[2-methoxyphenyl]phenylphosphino)ethane) and zinc powder in THF at 75 degrees C for 24 h, giving the corresponding (S)-phthalides 4a-e in 81-89% yields with 70-98% ee. A possible mechanism for the present catalytic reaction is proposed.

Application of 57-50-1, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 57-50-1.

Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. Name: Hoffer’s chlorosugar4330-21-6, Name is Hoffer’s chlorosugar, SMILES is O=C(O[C@@H]1[C@@H](COC(C2=CC=C(C)C=C2)=O)O[C@H](Cl)C1)C3=CC=C(C)C=C3, belongs to dioxole compound. In a article, author is Rosokha, Sergiy V., introduce new discover of the category.

Additions of inert tetrabutylammonium hexafluorophosphate (Bu4NPF6) to a solution of TMDO/DDQ in dichloromethane (where TMDO = 2,2,6,6-tetramethylbenzo[1,2-d, 4,5-d]bis[1,3]-dioxole, donor, and DDQ = dichlorodiyano-p-benzoquinone acceptor) is accompanied by drastic changes in the electronic spectrum which are related to the appearance of the DDQ and TMDO+ ion radicals and a decrease in the concentration of the neutral molecules and the charge transfer complex [TMDO,DDQ]. These changes point to a considerable rise (of about three orders of magnitude) in the apparent electron transfer equilibrium constant (K-ET) for this donor/acceptor pair upon increasing the electrolyte concentration from 0 to 0.5 M. Accordingly, the ion-radical fractions and K-ET values are higher in dichloromethane, at high electrolyte concentrations, than in acetonitrile (where the effect of Bu4NPF6 is less pronounced). Similar trends of the apparent equilibrium constants are observed for the tetramethyl-p-phenylenediamine/tetracynaoethylene pair. Electron-transfer equilibrium constants for both donor/acceptor dyads obtained from spectral measurements are related to those derived from the redox potentials of the reactants. The effects of media variations on the electron-transfer equilibria are discussed within the ion-pairing and ionic-activity frameworks.

I am very proud of our efforts over the past few months and hope to 4330-21-6 help many people in the next few years. Name: Hoffer’s chlorosugar.

Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

New research progress on 3130-19-6 in 2021. Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. In an article, author is Radice, Stefano, once mentioned the application of 3130-19-6, COA of Formula: https://www.ambeed.com/products/3130-19-6.html, Name is Bis(7-oxabicyclo[4.1.0]heptan-3-ylmethyl) adipate, molecular formula is C20H30O6, molecular weight is 366.4486, MDL number is MFCD00191811, category is dioxole. Now introduce a scientific discovery about this category.

In this paper is presented a study on the effects of physical treatments, namely electron beam irradiation or fluorination, on a perfluoropolymer copolymer of tetrafluoroethylene with 2,2,4-trifluoro-5-trifluoromethoxy-1,3-dioxole (Hyflon (R) AD copolymer). The analysis has been carried out by means of IR spectroscopy and quantum chemical modeling based on density functional theory; this combined experimental/ theoretical approach has proven effective for the interpretation of previously unassigned IR bands, which are associated to functional groups generated by polymer degradation and chain scission. We performed a systematic screening of chemical groups and structures compatible with degradation pathways that are possible from the chemical point of view: the chemical mechanisms and the correlation with the spectroscopic experimental data (both frequency and intensity) provide guidelines in understanding the phenomena. Moreover, the spectroscopic experimental/theoretical and chemical approaches allowed us to identify some chemical structures responsible for the unassigned IR bands in the C=O stretching frequency region above 1800 cm(-1), which is typical for carbonyl groups in fluorinated systems. (C) 2014 Elsevier B.V. All rights reserved.

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Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 4330-21-6, Name is Hoffer’s chlorosugar, SMILES is O=C(O[C@@H]1[C@@H](COC(C2=CC=C(C)C=C2)=O)O[C@H](Cl)C1)C3=CC=C(C)C=C3, in an article , author is Yeung, Sing Yee, once mentioned of 4330-21-6, Product Details of 4330-21-6.

Both the traditional Chinese medicinal fungus, Antrodia camphorata, and its secondary metabolite, 4,7-dimethoxy-5-methylbenzo[d][1,3]dioxole, have been reported to possess promising anticancer activity. In this work the natural product and analogues bearing more polar substituents were synthesised and assessed for antiproliferative activity in the NCI-60 screen. Although each compound inhibited the growth of some cell lines at 10 mu M, none had sufficient activity to warrant further investigation.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 4330-21-6. Product Details of 4330-21-6.

Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

Academic researchers, R&D teams, teachers, students, policy makers and the media all rely on us to share knowledge that is reliable, accurate and cutting-edge. 57-50-1, Name is Sucrose, SMILES is O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@H]1O[C@@]2(CO)[C@H]([C@@H]([C@@H](CO)O2)O)O, in an article , author is Semjonovs, Nikita, once mentioned of 57-50-1, Formula: https://www.ambeed.com/products/57-50-1.html.

The title compound, C23H25N3O4, {systematic name: 1-benzy1-4-[(3 aR,5R,6R,6aR)-6-benzyloxy-2,2-dimethyltetrahydrofuro [2,3-d] [1,3] dioxo1-5 y11-1H-1,2,3-triazolel, consists of a substituted 2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole. The furanose ring adopts an envelope conformation close to C3-exo, where the C atom substituted by the benzyloxy group is the flap. The fused dioxolane ring also adopts an envelope conformation, with the methylene C atom as the flap. In the crystal, molecules are linked by weak C-H center dot center dot center dot O hydrogen bonds, forming zigzag chains along [010].

Formula: https://www.ambeed.com/products/57-50-1.html, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 57-50-1 is helpful to your research.

Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

While the job of a research scientist varies, most chemistry careers in research are based in laboratories, where research is conducted by teams following scientific methods and standards. Computed Properties of https://www.ambeed.com/products/68515-73-1.html68515-73-1, Name is (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)tetrahydro-2H-Pyran-3,4,5-triol, SMILES is O[C@H]1C(OCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O, belongs to dioxole compound. In a article, author is Lai, Chun-Ze, introduce new discover of the category.

Fluorous media are the least polar and polarizable condensed phases known. Their use as membrane materials considerably increases the selectivity and robustness of ion-selective electrodes (ISEs). In this research, a fluorous amorphous perfluoropolymer was used for the first time as a matrix for an ISE membrane. Electrodes for pH measurements with membranes composed of poly[4,5-difluoro-2,2-bis(trifluoromethyl)-1,3-dioxole]-co-poly(tetrafluoroethylene) (87% dioxole monomer content; known as Teflon AF2400) as polymer matrix, a linear perfluorooligoether as plasticizer, sodium tetrakis[3,5-bis(perfluorohexyl)phenyl]borate providing for ionic sites, and bis[(perfluorooctyl)propyl]-2,2,2-trifluoroethylamine as H+ ionophore were investigated. All electrodes had excellent potentiometric selectivities, showed Nernstian responses to H+ over a wide pH range, exhibited enhanced mechanical stability, and maintained their selectivity over at least 4 weeks. For membranes of low ionophore concentration, the polymer affected the sensor selectivity noticeably at polymer concentrations exceeding 15%. Also, the membrane resistance increased quite strongly at high polymer concentrations, which cannot be explained by the Mackie-Meares obstruction model. The selectivities and resistances depend on the polymer concentration because of a functional group associated with Teflon AF2400, with a concentration of one functional group per 854 monomer units of the polymer. In the fluorous environment of these membranes, this functional group binds to Na+, K+, Ca2+, and the unprotonated ionophore with binding constants of 10(3.5), 10(1.8), 10(6.8), and 10(4.4) M-1, respectively. Potentiometric and spectroscopic evidence indicates that these functional groups are COCH groups formed by the hydrolysis of carboxylic acid fluoride (COF) groups originally present in Teflon AF2400. The use of higher ionophore concentrations removes the undesirable effect of these COOH groups almost completely. Alternatively, the C(=O)F groups can be eliminated chemically, or they can be used to readily introduce new functionalities.

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Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

As a society publisher, everything we do is to support the scientific community – so you can trust us to always act in your best interests, and get your work the international recognition that it deserves. Related Products of 68515-73-168515-73-1, Name is (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)tetrahydro-2H-Pyran-3,4,5-triol, SMILES is O[C@H]1C(OCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O, belongs to dioxole compound. In a article, author is Hayashi, Ryoji, introduce new discover of the category.

We searched for a strong and selective nonprostanoid IP agonist bearing piperidine and benzanilide moieties. Through optimization of substituents on the benzanilide moiety, the crucial part of the agonist, 43 (2-((1-(2-(N-(4-tolyl) benzo[d][1,3]dioxole-5-carboxamido) ethyl) piperidin-4-yl)oxy) acetic acid monohydrate monohydrochloride) was discovered and exhibited strong platelet aggregation inhibition (IC50 = 21 nM) and 100-fold selectivity for IP receptor over other PG receptors. The systemic exposure level and bioavailability after oral administration of 43 were also good in dog. (C) 2016 Elsevier Ltd. All rights reserved.

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1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. Application In Synthesis of Bis(7-oxabicyclo[4.1.0]heptan-3-ylmethyl) adipate3130-19-6, Name is Bis(7-oxabicyclo[4.1.0]heptan-3-ylmethyl) adipate, SMILES is O=C(CCCCC(OCC1CC2OC2CC1)=O)OCC3CC4OC4CC3, belongs to dioxole compound. In a article, author is CORTEZ, E, introduce new discover of the category.

1,3-Dioxole, OCH2OCH=CH, has been synthesized and its far-infrared and low-frequency Raman spectra have been analyzed. The gas-phase far-infrared spectrum shows a series of eleven single-quantum-jump and three triple-quantum-jump transitions in the 40-330 cm-1 region. The low-frequency Raman spectrum exhibits eight ring-puckering transitions corresponding to DELTAupsilon = 2 or 4 transitions in the 160-300-cm-1 region. The ring-puckering potential energy function was determined to be V(cm-1) = (1.59 x 10(6))x4 – (4.18 x 10(4))x2, where x is the ring puckering coordinate in angstroms. This function indicates that the molecule is puckered with a barrier to planarity of 275 cm-1 and a bending angle of 24-degrees. The unexpected nonplanarity of 1,3-dioxole is attributed to the anomeric effect which can be present in molecules with O-C-O linkages. Molecular mechanics calculations utilizing the MM3 parametrization predict a planar structure for this molecule. However, the anomeric effect dictates that each of the =C-O-C-O torsional angles should have a strong desire to increase from 0-degrees toward 90-degrees in order to optimize n-sigma* overlap. When the MM3 force field is modified to reflect this by increasing the magnitude of the 2-fold torsional potential energy term V2 to -5.965 kcal/mol, a reasonably good agreement between the experimental and molecular mechanics potential functions can be obtained.

Application In Synthesis of Bis(7-oxabicyclo[4.1.0]heptan-3-ylmethyl) adipate, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 3130-19-6.

Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

The dynamic chemical diversity of the numerous elements, ions and molecules that constitute the basis of life provides wide challenges and opportunities for research. 4330-21-6, Name is Hoffer’s chlorosugar, SMILES is O=C(O[C@@H]1[C@@H](COC(C2=CC=C(C)C=C2)=O)O[C@H](Cl)C1)C3=CC=C(C)C=C3, in an article , author is Skrobiszewski, Andrzej, once mentioned of 4330-21-6, Recommanded Product: Hoffer’s chlorosugar.

Eighteen racemic beta-aryl-gamma-lactones derived from simple aromatic aldehydes have been obtained in the chemical synthesis. Iodolactones (5c and 6c) were synthesized from (E)-4-(benzo[d][1′,3′]-dioxol-5′-yl)-but-3-en-2-one (1). Reductive dehalogenation of iodolactones 5a-c and 6a-c afforded gamma-ethyl-gamma-lactones (7a-c, 8a-c) whereas the unsaturated lactones (9a-c, 10a-c) were obtained by dehydrohalogenation of iodolactones. All synthesized lactones were fully characterized by spectroscopic data (NMR, IR, HRMS) and subjected to the tests on the antifeedant activity towards Tribolium confusum, Trogoderma granarium and Sitophilus granaries as well to the tests on the antifungal activity towards four Fusarium species. The biological tests allowed to find some relationships between the structure and biological activity of the compounds studied. gamma-Ethyl- gamma-lactones 7a-c, 8a-c and unsaturated lactones 9a-c, 10a-c were usually stronger antifeedants than their parent iodolactones 5a-c and 6a-c. trans-Iodolactones 6a-c were more active than cis isomers 5a-c both in antifeedant and antifungal assays. The structure of aromatic substituent was the key factor in antifungal activity. The lactones with benzo [d][1,3]dioxole ring (5c, 6c, 7c, 8c, 9c) were the most active whereas those with unsubstituted benzene ring exhibited almost no activity.

Recommanded Product: Hoffer’s chlorosugar, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 4330-21-6.

Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem

You could be based in a university, combining chemical research with teaching; in a pharmaceutical company, working on developing and trialing new drugs; helping to ensure national healthcare provision keeps pace with new discoveries. COA of Formula: https://www.ambeed.com/products/68515-73-1.html68515-73-1, Name is (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)tetrahydro-2H-Pyran-3,4,5-triol, SMILES is O[C@H]1C(OCCCCCCCCCC)O[C@H](CO)[C@@H](O)[C@@H]1O, belongs to dioxole compound. In a article, author is Oh, Chang Ho, introduce new discover of the category.

Atom-economical syntheses of isomeric 5-acetoxy-2-alkyl-2-cyclopentenones (2) and acetoxymethyl (x-alkylailen ones (3) have been described via Au-catalyzed hydrative rearrangement of 1,1-diethynyl-carbinol acetates (1). In anhydrous condition, Au(I)-catalyzed [3,3]-rearrangement of 1 afforded the 3-alkynylallenyl acetate 4 in low yield. Treatment of 1 with Au(I) catalyst in wet CH2Cl2 produced either 2 or 3 as a major product depending on the temperature, reaction time. and catalyst loading. D has been proposed as an intermediate, which might be formed via Au(I)-induced internal oxacyclization of the intermediate 4 followed by chemoselective nucleophilic attack by the water molecule. Formation of 2 or 3 might be explained via sequential 1,3-dioxole ring opening and gold-promoted 5-endo-dig carbocyclization or simple protonation of the intermediate D, respectively.

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Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem