Tag: M.W=200-250

Tu, Yuan-hong published the artcileSynthesis of vanillin 1,2-propylene glycol acetal catalyzed by silica supported ferric sulfate, SDS of cas: 68527-74-2, the publication is Riyong Huaxue Gongye (2008), 38(1), 39-41, database is CAplus.

Vanillin 1,2-propylene glycol acetal was synthesized using 1,2 -propylene glycol and vanillin as starting materials and silica supported ferric sulfate as catalyst. Effects of factors on yield of product, such as molar ratio of the reactants, reaction time, catalyst dosage and its stability, were investigated. Exptl. results showed that the preferential conditions were as follows: based on 0.1 mol of vanillin, the molar ratio of vanillin to 1,2 -propylene glycol was 1.0: 1.4; the dosage of catalyst was 2.5% of the total weight of the reactants; the amount of cyclohexane as water stripping agent was 12 mL; the reaction time was 3.0 h; under these conditions, the yield could achieve 86.0%.

Riyong Huaxue Gongye published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C6H10F3NO, SDS of cas: 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Mao, Deshou published the artcileAnalysis of volatile constituents from cocoa extract (Theobroma cacao. L) by using stir bar sorptive extraction-thermal desorption/gas chromatography-mass spectrometry, Product Details of C11H14O4, the publication is Xiangliao Xiangjing Huazhuangpin (2012), 5-9, 13, database is CAplus.

The volatile constituents of Cocoa extract were identified by using stir bar sorptive extraction-thermal desorption/gas chromatog.-mass spectrometry (SBSE-TDU/GC-MS). With the MS library search and retention index comparison, 73 compounds were confirmed with PDMS twister, and the main constituents included isovaleric acid (25.28%), isovaleraldehyde propylene glycol acetal (14.57%), benzyl acetate (10.60%), 1,2-propylene glycol (9.17%), phenethyl alc. (9.00%), dibenzyl ketone (5.00%), phenethyl phenylacetate (4.50%), isoamyl isovalerate (3.63%), 2,3,5-trimethylpyrazine (2.34%), 2-methoxy-3-Me pyrazine (2.29%), 2-isopropyl-5-methyl-2-hexenal (1.53%), Et linoleate (1.25%) and acetic acid (1.10%), while with EG-silicone twister, 59 chems. were determined, which included the following main compounds: 2,3,5-trimethylpyrazin (63.59%), acetic acid (12.06%), isovaleraldehyde propylene glycol acetal (4.96%), benzyl acetate (3.92%), palmitic acid (1.89%), guaiacol (1.41%), isovaleric acid (1.08%), dibenzyl ketone (1.08%) and glycerin (1.01%). The research provided technol. supports for exploitation and quality control of cocoa extract

Xiangliao Xiangjing Huazhuangpin published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Product Details of C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Liu, Yu-ping published the artcileSynthesis of vanillin propylene glycol acetal catalyzed by NaHSO₄, Synthetic Route of 68527-74-2, the publication is Jingxi Huagong (2004), 21(11), 831-832, 846, database is CAplus.

Synthesis of vanillin propylene glycol acetal (I) was studied. Factors influencing the yield, such as different dehydrating agents, catalyst amounts, mole ratio of materials, were discussed and the better reaction conditions were determined Thus, 0.48 mol propylene glycol reacted with 0.2 mol vanillin in the presence of 1 g NaHSO₄ as catalyst and 100 mL benzene to give I in 85.2% yield. The structure of I was identified by means of GC, refractive index, IR and GC-MS.

Jingxi Huagong published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Synthetic Route of 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Gan, Wangbao published the artcileSynthesis of vanillin propylene glycol acetal by microwave irradiation and its application in flavors, HPLC of Formula: 68527-74-2, the publication is Xiangliao Xiangjing Huazhuangpin (2008), 1-3, database is CAplus.

Vanillin propylene glycol acetal was synthesized under microwave irradiation from vanillin and 1,2-propylene glycol in the presence of citric acid. The factors that influenced the reaction under microwave heating were investigated, the yield of 41.04% was obtained under conditions of 1,2-propylene glycol_vanillin=1.2:1 (mol/mol), citric acid 2 g/mol (based on the amount of vanillin), irradiation power 600W, time 12 min. Its application in baked food was tested.

Xiangliao Xiangjing Huazhuangpin published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, HPLC of Formula: 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Susanti, Nora published the artcileIncreased stability of Styrax benzoin extract and fraction with the addition of Cosolvents, Application of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, the publication is Journal of Physics: Conference Series (2021), 012049, database is CAplus.

The gum resin of S. benzoin is a very important commodity in the world of industrialization and really needs the attention of the frankincense farmers. This is based on the many benefits of the plants which are only limited to livelihoods.The purpose of the research are to know the results of increasing the stability of the gum styrax benzoin with the addition of cosolvents. The identification of the components of secondary metabolites using phytochem. screening.The methodol. of the research is maceration the gum styrax benzoin ash with Etanol solvent until all samples are immersed and carried out in a glass bottle for three days. The research was continued with identification of the components of secondary metabolites using phytochem. screening. The findings of the research is anal. using phytochem. screening shows the secondary metabolites styrax benzoin such as alkaloids, flavonoid, tannin, saponin, and terpenoid. The limitations of the research is focuses on 3 variations in the Cosolvent of propylene glycol, polyethylene glycol and triethanolamine. The reserch have value specifically the gum styrax benzoin is used as the solubility of several pharmaceutical compounds

Journal of Physics: Conference Series published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C44H28ClFeN4, Application of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kerber, Paul J. published the artcileKinetics of Aldehyde Flavorant-Acetal Formation in E-Liquids with Different E-Cigarette Solvents and Common Additives Studied by ¹H NMR Spectroscopy, Name: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, the publication is Chemical Research in Toxicology (2022), 35(8), 1410-1417, database is CAplus and MEDLINE.

Flavorants, nicotine, and organic acids are common additives found in the e-liquid carrier solvent, propylene glycol (PG) and/or glycerol (GL), at various concentrations Some of the most concentrated and prevalent flavorants in e-liquids include trans-cinnamaldehyde, vanillin, and benzaldehyde. Aldehyde flavorants have been shown to react with PG and GL to form flavorant-PG and -GL acetals that have unique toxicity properties in e-liquids before aerosolization. However, there is still much that remains unknown about the effects of different e-cigarette solvents, water, nicotine, and organic acids on the rate of acetalization in e-liquids We used ¹H NMR spectroscopy to determine the first-order initial rate constant, half-life, and % acetal formed at equilibrium for flavorant-acetal formation in simulated e-liquids Herein, we report that acetalization generally occurs at a faster rate and produces greater yields in e-liquids with higher ratios of GL (relative to PG). trans-Cinnamaldehyde acetals formed the fastest in 100% PG-simulated e-liquids, followed by benzaldehyde and vanillin based on their half-lives and rate constants The acetal yield was greatest for benzaldehyde in PG e-liquids, followed by trans-cinnamaldehyde and vanillin. Acetalization in PG e-liquids containing aldehyde flavorants was inhibited by water and nicotine but catalyzed by benzoic acid. Flavorant-PG acetal formation was generally delayed in the presence of nicotine, even if benzoic acid was present at 2-, 4-, or 10-fold the nicotine concentration, as compared to the PG e-liquids with 2.5 mg/mL flavorant. Thus, com. e-liquids with aldehyde flavorants containing a higher GL ratio (relative to PG), little water, no nicotine, nicotine with excess organic acids, or organic acids without nicotine would undergo acetalization the fastest and with the highest yield. Many com. e-liquids must therefore contain significant amounts of flavorant acetals.

Chemical Research in Toxicology published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Name: 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Huang, Shi-jie published the artcileQuality control of tobacco flavor by GC-MS combined with clustering analysis, COA of Formula: C11H14O4, the publication is Anhui Nongye Kexue (2009), 37(14), 6344-6346, database is CAplus.

[Objective] The research aimed to establish the GC-MS fingerprint of tobacco flavor A# and provide new methods for the quality control of tobacco flavor. [Method] Eight batches of tobacco flavor A# were determined by GC-MS combined with clustering anal. [Result] The fingerprints of tobacco flavor A#, including 23 mutual peaks were developed after determination of 6 batches of flavor according to the clustering anal. [Conclusion] The separation effect of peaks in fingerprints is better and the characteristic is also obvious. The RSD values of precision and reproducibility are less than 3%. This method can be used for the quality control of tobacco flavor.

Anhui Nongye Kexue published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, COA of Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Luo, Zhi-chen published the artcileSyhthesis of vanillin 1, 2-propylene glycol acetal with copper p-toluene sulfonate catalyst, COA of Formula: C11H14O4, the publication is Huaxue Shijie (2010), 51(11), 675-677, database is CAplus.

Vanillin-1,2-propylene glycol acetal was synthesized from vanillin and 1,2-propylene glycol using copper p-toluene sulfonate as catalyst and benzene as water stripping agent. The effects of molar ratio of the reactants, catalyst dosage and reaction time on yield were investigated. Copper p-toluene sulfonate showed high catalytic activity, and the catalyst was reused for 3 times. The preferential conditions are as follows: based on 15.2g(0.1 mol) of vanillin, the molar ratio of vanillin to 1,2-propylene glycol is 1: 1.60; the dosage of catalyst is 0.9g, the amount of benzene as water stripping agent is 25 mL; and the reaction time is 2.5 h. The yield can achieve 87%.

Huaxue Shijie published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, COA of Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Moreno, Jose Maria published the artcileMOFs based on 1D structural sub-domains with Bronsted acid and redox active sites as effective bi-functional catalysts, Quality Control of 68527-74-2, the publication is Catalysis Science & Technology (2020), 10(11), 3572-3585, database is CAplus.

A novel family of lamellar MOF-type materials, which contain Bronsted acid sites together with redox active centers, based on assembled 1D organic-inorganic nanoribbons were obtained through direct solvothermal synthesis routes, using specific monotopic benzylcarboxylate spacers with thiol substituents in the para-position like structural modulator compounds and effective post-synthesis oxidized treatments to generate accessible sulfonic groups. Low-dimensional aluminum metal-organic materials, containing free sulfonic pendant groups (Al-ITQ-SO₃H), were successfully tested in several acid reactions, such as acetalization, esterification and ring opening of epoxides with a significant impact on fine chem. processes. The direct introduction of stabilized Pd nanoparticles, cohabitating with pendant sulfonic groups, allowed the preparation of active bi-functional MOF-type hybrid materials (Al-ITQ-SO₃H/Pd) capable of carrying out one-pot two-step oxidation-acetalization reactions, exhibiting high yield and high activity during consecutive catalytic cycles.

Catalysis Science & Technology published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, Quality Control of 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Sipes, I. G. published the artcileHydroxy- and alkoxy-substituted benzyl derivatives (addendum), Quality Control of 68527-74-2, the publication is WHO Food Additives Series (2009), 533-548, database is CAplus.

A review discusses the assessment of dietary exposure, absorption, distribution, metabolism, and safety of hydroxy- and alkoxy-substituted benzyl derivatives for use as flavoring agents. The acute toxicity, genotoxicity, and reproductive/developmental toxicity of these flavoring agents are also tackled.

WHO Food Additives Series published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C12H9NO, Quality Control of 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem