Tag: M.W=100-150

Jiang, Dabo published the artcileSynthesis of acetals (ketals) catalyzed by phosphogypsum, COA of Formula: C8H14O2, the publication is Shiyou Huagong (2016), 45(3), 330-334, database is CAplus.

The synthesis of acetals (ketones) catalyzed by phosphogypsum (PG) was explored. The effects of the mole ratio of ethylene glycol to cyclohexanone, catalyst dosage, reaction time, water-carrying agents, cyclohexane dosage and catalyst reuse times on the yields of cyclohexanone glycol ketal were investigated. The results showed that the yield of cyclohexanone glycol ketal reached 99.9% under the conditions of catalyst dosage 7.5% (w), mole ratio of ethylene glycol to cyclohexanone 1.5, cyclohexane 16 mL and reaction time 2.5 h. After PG was reused 8 times, the yield of cyclohexanone glycol ketal still reached 98.5%. The catalytic activities of PG in the syntheses of 12 acetals (ketones) were studied. PG indicated excellent catalytic performances for the synthesis of the 12 acetals (ketones) and was a environmentally friendly solid acid catalyst for the utilization of the byproduct PG from phosphate industry.

Shiyou Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, COA of Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Sun, Xudong published the artcileSynthesis of a novel multi-SO₃H functionalized ionic liquid and its catalytic activities, Application of 1,4-Dioxaspiro[4.5]decane, the publication is Kinetics and Catalysis (2012), 53(3), 301-305, database is CAplus.

A novel multi-SO₃H functionalized ionic liquid is synthesized and a detailed account of its catalytic activities in acetalization and acetylation is given. The results showed that the ionic liquid is very efficient in the conventional acid-catalyzed reactions with good to excellent yields within a short reaction time. Operational simplicity, small amounts required, low cost of the catalyst, high yields, scalability and reusability are the key features of this methodol., which indicates the high potentialities of the novel ionic liquid to be used in environmentally friendly processes.

Kinetics and Catalysis published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C7H5BF4O3, Application of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Hu, Jing published the artcileLeather odor analysis by GC-MS and simulation, HPLC of Formula: 177-10-6, the publication is Zhongguo Pige (2012), 41(5), 28-31, database is CAplus.

The volatile organic components of different leathers were extracted by Soxhlet extraction and determined with gas chromatog. and mass spectrometry (GC-MS). The leather fragrance was simulated by the sensor anal. based on the GC-MS results. The results show that there are many volatile organic components in the odor of the unfinished and finished sheep garment leathers, cow garment leather and cow car seat leather. These components are hydrocarbons, esters, aldehydes, acids, ethers and ketones, etc. Based on the GC-MS results, the leather fragrance is further prepared

Zhongguo Pige published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, HPLC of Formula: 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Ovsyannikova, M. N. published the artcileAntibacterial activity of substituted 1,3-dioxolanes, Computed Properties of 177-10-6, the publication is Pharmaceutical Chemistry Journal (2013), 47(3), 142-145, database is CAplus.

Cyclic ketals and acetals (1,3-dioxolanes) substituted at positions 2 and 4 of the dioxolane ring, prepared by condensation of glycerol and ethylene glycol with aldehydes and ketones, exhibited antimicrobial activity against Gram-pos. and Gram-neg. bacteria. This activity, which may be associated with the antiradical activity of the compounds and depended on their hydrophilic-hydrophobic balance, allows targeted variation in structural parameters for the creation of new active compounds Cyclic ketals with high antimicrobial activity can be used as antiseptics for sterilization of working surfaces and instruments.

Pharmaceutical Chemistry Journal published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Computed Properties of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Varfolomeev, S. D. published the artcileNew possibilities in the synthesis of fuel oxygenates from renewable sources, Synthetic Route of 177-10-6, the publication is Russian Chemical Bulletin (2019), 68(4), 717-724, database is CAplus.

A general problem in the production of the main types of liquid biofuel, bioethanol and biodiesel, is that renewable resources are not utilized completely. These are ballast polyols: hemicellulose or its structural units, pentaat. monosaccharides (xylose and arabinose), and biodiesel glycerol. The problem of utilization of these compounds by transforming them into a hydrophobized fuel form by the conversion to cyclic ketals (CK) during condensation with lower carbonyl compounds is reviewed. The CK-ethanol pair significantly increases the octane number and provides phase stability of fuel compositions The ability of CK to inhibit radical processes responsible for fuel characteristics was studied in model reactions with Ph radicals and at. chlorine. The carbon-centered radicals formed in protic media are transformed into more stable cyclic radical cations. Alternative methods of processing natural raw materials using biocatalysis and supercritical fluid technologies are analyzed.

Russian Chemical Bulletin published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C10H12F6N4O6PdS2, Synthetic Route of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Brockway, Anthony J. published the artcileSynthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) – An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity, COA of Formula: C8H14O2, the publication is Bioorganic & Medicinal Chemistry (2017), 25(20), 5433-5440, database is CAplus and MEDLINE.

We describe our efforts to improve the pharmacokinetic properties of a mechanism-based suicide inhibitor of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (AdoMetDC), essential for the survival of the eukaryotic parasite Trypanosoma brucei responsible for Human African Trypanosomiasis (HAT). The lead compound, 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (1, also known as MDL 73811, or AbeAdo), has curative efficacy at a low dosage in a hemolymphatic model of HAT but displayed no demonstrable effect in a mouse model of the CNS stage of HAT due to poor blood-brain barrier permeation. Therefore, we prepared and evaluated an extensive set of analogs with modifications in the aminobutenyl side chain, the 5′-amine, the ribose, and the purine fragments. Although we gained valuable structure-activity insights from this comprehensive dataset, we did not gain traction on improving the prospects for CNS penetration while retaining the potent antiparasitic activity and metabolic stability of the lead compound 1.

Bioorganic & Medicinal Chemistry published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, COA of Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Li, Guixian published the artcileEfficient and highly-selective cycloaddition of epoxides with carbonyl compound over Wells-Dawson type heteropolyacids, COA of Formula: C6H12O2, the publication is Journal of Molecular Catalysis A: Chemical (2005), 236(1-2), 72-76, database is CAplus.

Wells-Dawson type Heteropolyacids (H_6+nP₂Mo_18-nV_nO₆₂) (n = 0-2, 4) have proved to be efficient heterogeneous catalysts for the reaction of epoxides with carbonyl compounds to form 1,3-dioxolane derivatives Especially, when H₇P₂Mo₁₇VO₆₂ was used to catalyze the reaction between acetone and epoxypropane, the selectivity to 1,3-dioxolane reached to 93.3% with nearly complete conversion of epoxide and 1.1 × 10⁴ h^-1 of TOF.

Journal of Molecular Catalysis A: Chemical published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, COA of Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

He, Si-Qing published the artcilePreparation of carboxyethyltin group-functionalized highly ordered mesoporous organosilica composite material with double acid sites, Name: 1,4-Dioxaspiro[4.5]decane, the publication is Journal of Materials Science (2019), 54(6), 4601-4618, database is CAplus.

A series of highly ordered mesoporous ethane-bridged organosilica composite materials functionalized by carboxyethyltin group, SnR-Si(Et)Si-X (SnR and Si(Et)Si denote [Sn(CH₂)₂COOH]³⁺ and ethane-bridged organosilica groups, resp.), were successfully designed through one-step co-condensation-hydrothermal method. The pore morphol. and textural properties, Sn(IV) coordination environment, the type of acid site, Bronsted and Lewis acid strength were systematically characterized by LXRD, TEM observation, N₂ porosimetry measurements, MAS NMR (²⁹Si, ¹³C, ¹¹⁹Sn), UV-Vis diffuse reflectance spectrum, as well as ¹H and ³¹P MAS NMR, FT-IR anal. of adsorbed pyridine, acid-base titration Composite materials SnR-Si(Et)Si-X possess Bronsted and Lewis acid sites, which originates from -COOH in [Sn(CH₂)₂COOH]³⁺ group and bridging OH in [Si(OH)SnR] group as well as tetrahedral coordination framework Sn(IV) in the open configuration [SnR(SiO)₃(OH)], resp. The above 2D hexagonal mesoporous structure with unique textural properties, double acid sites (Bronsted and Lewis acid sites) and hydrophobic surface make SnR-Si(Et)Si-X exhibit excellent acid catalytic activity, reusability and water tolerance toward ketalization of cyclohexanone with glycol in absence of azeotrope agent at low temperature

Journal of Materials Science published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Name: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Li, Zi-Liang published the artcileThree molybdophosphates based on Strandberg-type anions and Zn(II)-H₂biim/H₂O subunits: syntheses, structures and catalytic properties, Recommanded Product: 1,4-Dioxaspiro[4.5]decane, the publication is Dalton Transactions (2014), 43(15), 5840-5846, database is CAplus and MEDLINE.

Three new inorganic-organic hybrid compounds based on Strandberg-type anions and Zn(II)-H₂biim/H₂O subunits, namely {H₄(H₂biim)₃}[Zn(H₂biim)(H₃biim)(H₂O)(HP₂Mo₅O₂₃)]₂·3H₂O (1), {H₉(H₂biim)₇}[(μ-biim){(Zn(H₂O)₂)_0.5(HP₂Mo₅O₂₃)}₂]·7H₂O (2) and {H₇(H₂biim)₇}[Zn(H₂biim)(H₂O)₂(HP₂Mo₅O₂₃)][H₂P₂Mo₅O₂₃]·8H₂O (3) (H₂biim = 2,2′-biimidazole), have been synthesized in aqueous solutions and characterized. They were also used as efficient and reusable catalysts for the protection of carbonyl compounds Their fascinating structural features are that mono Zn(II)-supporting biphosphopentamolybdate ({P₂Mo₅}) clusters exist in their crystal structures, and the nitrogen donor ligand H₂biim exhibits three different coordination modes in these three compounds, resp.: for 1, two 2,2′-biimidazole mols., as mono- and bidentate ligands coordinate to the same Zn(II) ion; for 2, one bi-neg. tetradentate ligand μ-biim bridges two Zn(II) ions, while for 3, one neutral bidentate H₂biim ligand links one Zn(II) ion. Most importantly, compounds 1–3 represent the first example where Strandberg-type POMs are used as acid-catalysts in an organic reaction.

Dalton Transactions published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Recommanded Product: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zhu, Zai-ming published the artcileSynthesis of cyclohexanone ethylene ketal catalyzed by Keggin-type Ni/Cu/2,2′-H₂ biim-tungstosilicates, Application of 1,4-Dioxaspiro[4.5]decane, the publication is Yingyong Huagong (2015), 44(5), 882-886, 889, database is CAplus.

A series of Keggin-type Ni/Cu/H₂biim-tungstosilicates (H₂ biim = 2,2′-biimidazole) were synthesized with the parent tungstosilicic acid as a reactant and H₂ biim, Ni²⁺/Cu²⁺ and their complexes as raw materials by a direct precipitation method. They were characterized by single crystal XRD, IR and elemental anal. The acid-catalyzed synthesis of cyclohexanone ethylene ketal by the reaction of cyclohexanone with ethylene glycol was selected as a model reaction. The catalytic activities of these tungstosilicates were investigated. The results show that the introduction of large cation reduced the POM’s solubility, and the catalysts can be recycled and reused, so that their utilization can be improved. Moreover, the catalytic activities of these heterogeneous catalysts were almost unchanged after three cycles.

Yingyong Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C15H23BO2, Application of 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem