Tag: 666.8022

Synthesis of Trisaccharides by Hetero-Diels-Alder Welding of Two Monosaccharide Units was written by Himanen, Jatta A.;Pihko, Petri M.. And the article was included in European Journal of Organic Chemistry in 2012.SDS of cas: 171086-52-5 This article mentions the following:

A new strategy for the synthesis of di- and trisaccharides based on the de novo synthesis of the linking saccharide unit is presented. In this strategy, functionalized monosaccharide building blocks already incorporating the glycosidic linkages are welded together using a metal-catalyzed hetero-Diels-Alder (HDA) reaction to generate a new monosaccharide unit between them. The highest yields and selectivities in the HDA reaction were obtained by using chiral Schiff base chromium complexes. Disaccharide products were accessible by reaction of Danishefsky’s diene with acetyl- and benzyl-protected galactoside aldehydes. For the synthesis of trisaccharide products, acetyl-protected glucose or galactose-derived dienes were fused with monosaccharide-derived aldehydes using chromium catalysts for the HDA reaction. The desired trisaccharide products were obtained in moderate to good yields with excellent stereoselectivity. The central pyranulose-ring generated in the process possessed an L-cis-enulose configuration according to NMR spectroscopy and modeling studies. In the experiment, the researchers used many compounds, for example, ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) (cas: 171086-52-5SDS of cas: 171086-52-5).

((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) (cas: 171086-52-5) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.SDS of cas: 171086-52-5

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Enantioselective conjugate additions of aldoximes to 3-crotonoyl-2-oxazolidinone and 1-crotonoyl-3-phenyl-2-imidazolidinone catalyzed by the aqua complex between R,R-DBFOX/Ph and zinc(II) perchlorate was written by Nakama, Kimitaka;Seki, Sumito;Kanemasa, Shuji. And the article was included in Tetrahedron Letters in 2002.Safety of ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) This article mentions the following:

Conjugate addition reactions of aldoximes to 3-crotonoyl-2-oxazolidinone and to 1-crotonoyl-3-phenyl-2-imidazolidinone are accelerated in the presence of a catalytic amount of Lewis acids. The chiral ligands included (4R,4′R)-2,2′-(4,6-dibenzofurandiyl)bis[4,5-dihydro-4-phenyloxazole] (I), (4S,4′S)-2,2′-(1-methylethylidene)bis[4-(1,1-dimethylethyl)-4,5-dihydrooxazole], (4R,4′R)-2,2′-(1-methylethylidene)bis[4,5-dihydro-4-phenyloxazole], 2,6-bis[(4R)-4,5-dihydro-4-phenyl-2-oxazolyl]pyridine, (4S,5S)-2,2-dimethyl-α,α,α’,α’-tetra-1-naphthalenyl-1,3-dioxolane-4,5-dimethanol. The most effective catalyst was derived from zinc perchlorate hexahydrate and I. The reaction of 2-furancarboxaldehyde oxime in dichloromethane in the presence of I-zinc perchlorate hexahydrate complex gave a moderate enantioselectivity of 64% ee at 0°C. Reactions using other metal complexes are also discussed. In the experiment, the researchers used many compounds, for example, ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) (cas: 171086-52-5Safety of ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol)).

((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) (cas: 171086-52-5) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Safety of ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol)

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of Trisaccharides by Hetero-Diels-Alder Welding of Two Monosaccharide Units was written by Himanen, Jatta A.;Pihko, Petri M.. And the article was included in European Journal of Organic Chemistry in 2012.SDS of cas: 171086-52-5 This article mentions the following:

A new strategy for the synthesis of di- and trisaccharides based on the de novo synthesis of the linking saccharide unit is presented. In this strategy, functionalized monosaccharide building blocks already incorporating the glycosidic linkages are welded together using a metal-catalyzed hetero-Diels-Alder (HDA) reaction to generate a new monosaccharide unit between them. The highest yields and selectivities in the HDA reaction were obtained by using chiral Schiff base chromium complexes. Disaccharide products were accessible by reaction of Danishefsky’s diene with acetyl- and benzyl-protected galactoside aldehydes. For the synthesis of trisaccharide products, acetyl-protected glucose or galactose-derived dienes were fused with monosaccharide-derived aldehydes using chromium catalysts for the HDA reaction. The desired trisaccharide products were obtained in moderate to good yields with excellent stereoselectivity. The central pyranulose-ring generated in the process possessed an L-cis-enulose configuration according to NMR spectroscopy and modeling studies. In the experiment, the researchers used many compounds, for example, ((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) (cas: 171086-52-5SDS of cas: 171086-52-5).

((4S,5S)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(di(naphthalen-1-yl)methanol) (cas: 171086-52-5) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.SDS of cas: 171086-52-5

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem