Tag: 200-300

Synthesis, characterization, and structures of α-substituted selenenyl-acetophenones was written by Hodage, Ananda S.;Phadnis, Prasad P.;Wadawale, Amey;Priyadarsini, K. I.;Jain, Vimal K.. And the article was included in Phosphorus, Sulfur and Silicon and the Related Elements in 2014.Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

A series of α-substituted selenenyl acetophenone derivatives of the types, [PhC(OCH₂CH₂O)CH₂Se]₂, [PhC(OCH₂CH₂O)CH₂SeR], (PhCOCH₂Se)₂, and [PhCOCH₂SeR] were prepared These compounds were characterized by elemental analyses, IR and NMR (¹H, ¹³C, ⁷⁷Se) spectroscopy. The structures were established on the basis of the spectroscopic data and confirmed by single crystal x-ray diffraction anal. of bis(1-phenyldioxolonylmethyl) diselenide [monoclinic, space group I2/a, a 11.934 (3), b 10.872 (2), c 15.133 (6) Å, α 90.00, β 95.00, γ 90.00°, V 1955.3 (10) ų, Z 4] and bis(phenacyl) diselenide [orthorhombic, space group Pbca, a 8.705 (3), b 17.760 (9), c 19.517 (7) Å, α 90.00, β 90.00, γ 90.00°, V 3017 (2) ų, Z 8]. The former shows intramol. Se- – -O interaction, while the latter exhibits inter-mol. nonbonding Se- – -O interaction. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation and reactions of N-phenacyl-N-tosylhydroxylamine and -hydrazines was written by Wessig, Pablo;Henning, Hans Georg. And the article was included in Liebigs Annalen der Chemie in 1991.Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

O-Alkyl-N-phenacyl-N-tosylhydroxylamines PhCOCH₂NTsOCH₂R (I; Ts = tosyl; R = H, Ph, p-BrC₆H₄) were prepared in two steps from O-alkylhydroxylamines. In the presence of a base, I undergo rearrangement and cleavage to N-tosylphenacylamine and aldehydes RCHO. N-Alkyl-N‘-phenacyl-N,N‘-ditosylhydrazines TsNR¹NR²Ts (R¹ = R² = CH₂COPh or CH₂CO₂Et; R¹ = CH₂COPh, R² = CH₂Ph) were obtained by stepwise treatment of N,N‘-ditosylhydrazine with alkyl halides and phenacyl bromide/potassium tert-butoxide/DMF. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis and reactivity of some α-bromoketals was written by Kahlert, E. U.;Zymalkowski, F.. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 1975.SDS of cas: 3418-21-1 This article mentions the following:

Ketals I [X = (CH2)n, n = 1-3; OCH2] and II (R = H, Me, Et), prepared by reaction of the bromo ketone with ethylene glycol, were treated with secondary amines to give α,β-unsaturated ketals. If elimination of HBr was impossible, Br was substituted by amine. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1SDS of cas: 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.SDS of cas: 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Electrochemical oxidation of conjugated arylolefins to α-bromoketals was written by Nikishin, Gennady I.;Elinson, Michail N.;Makhova, Irina V.. And the article was included in Tetrahedron Letters in 1988.Recommanded Product: 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

Conjugated arylolefins electrolyzed in alcs. in the presence of alkali metal bromides were transformed into α-bromoketals. Thus RC₆H₄CH:CHR¹ (R = R¹ = H; R = p-Me, R = H; R = m-Cl, R¹ = H; R = H, R¹ = Me; R = p-MeO, R¹ = Me) was electrolyzed in MeOH containing NaBr in an undivided cell with a Pt anode, Cu-Zn (60:40) cathode at 60° under constant c.d. 220 mA/cm². RC₆H₄C(OMe)₂CHR¹Br was formed. Electrolysis of C₆H₅CH:CH₂ in ethylene glycol gave cyclic α-bromoketal. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Recommanded Product: 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

One-pot synthesis of some new α-bromoketals and acetals via 1,8-diazabicyclo[5.4.0] undec-7-ene-hydrobromide-perbromide was written by Hajizadeh, Neda;Bakavoli, Mehdi;Pordel, Mehdi. And the article was included in Iranian Journal of Chemistry & Chemical Engineering in 2017.Recommanded Product: 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

α-Bromoketals and acetals are important synthetic precursors in organic synthesis. In this work, some new α-bromoketals are synthesized by the reaction of aryl Me ketones with diols in the presence of 1,8-diazabicyclo[5.4.0] undec-7-ene (DBU) hydrobromide-perbromide in good isolated yields. The latter compound converts aldehydes to acetals and serves as a new and efficient reagent for the synthesis of acetals. Comparative studies of the preparation of α-bromoketal and acetals using some reported methods vs. the present method show that DBUH-Br₃ is one of the most efficient reagents for the preparation of these compounds Conversion of carbonyl compounds to corresponding α-bromoketals and acetals in the presence of DBUH-Br₃ under microwave irradiation is also described. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Recommanded Product: 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Recommanded Product: 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

A convenient procedure for the synthesis of acetals from α-halo ketones was written by Carlson, Rolf;Gautun, Hanna;Westerlund, Andreas. And the article was included in Advanced Synthesis & Catalysis in 2002.Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane This article mentions the following:

A study for determining the scope and limitations of a procedure for synthesizing ethylene acetals from haloketones is presented. The method uses 1,2-bis(trimethylsilyloxy)ethane, BTSE, as reagent and Nafion-TMS as catalyst. Two procedures have been tested: (A) stoichiometric amounts of the haloketone and BTSE and a catalytic amount of Nafion-TMS were heated to reflux in chloroform solution, and (B) stoichiometric amounts of the reactants and a catalytic amount of Nafion-TMS were heated to 90-100°C in the absence of solvent. The following ketones have been tested: 2-bromo-1-phenyl-1-ethanone, 2-bromo-cyclopentenone, 3-bromo-3-methyl-2-butanone, 3-chloro-3-methyl-2-butanone, 1-bromo-3,3-dimethyl-2-butanone, 1-chloro-3,3-dimethyl-2-butanone, 2-bromocyclohexanone, 2-chloro-1-cyclohexyl-1-ethanone, 1,1-dibromo-3,3-dimethyl-2-butanone, 1,3-dibromo-3-methyl-2-butanone, 1,3-dibromo-2-butanone, 1,3-dibromo-2-propanone, 2-chloro-1-phenyl-1-ethanone, and endo-2-bromocamphor. Yields were in the range 57-100% with the exceptions of endo-2-bromocamphor which afforded <10% yield and the dibromoketones 1,1-dibromo-3,3-dimethyl-2-butanone and 1,3-dibromo-3-methyl-2-butanone for which the method failed. Factors determining the scope and limitations are briefly discussed. Full exptl. details and spectroscopic data of the acetals are given. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Quality Control of 2-(Bromomethyl)-2-phenyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

One-step for the preparation of α-haloacetal of ketones with N-bromosuccinimide/N-chlorosuccinimide (NBS/NCS) and ethylene glycol was written by Zheng, Zubiao;Han, Bingbing;Wu, Fang;Shi, Tengfei;Liu, Jie;Zhang, Yong;Hao, Jialong. And the article was included in Tetrahedron in 2016.Formula: C10H11BrO2 This article mentions the following:

A new process that could directly prepare α-haloacetal of ketones from various ketones with N-halosuccinimide (NBS/NCS) and ethylene glycol in one step without any other catalysts is reported. The effects of solvents, NBS/NCS and reaction temperature were studied. Under the optimal condition, most of α-haloacetals of ketones were obtained in 90-100% yield. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Formula: C10H11BrO2).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Formula: C10H11BrO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Purines. L. Synthesis and antileukemic activity of the antibiotic guanine 7-oxide and its 9-substituted derivatives was written by Ogawa, Kazuo;Nishii, Masahiro;Inagaki, Jinichiro;Nohara, Fujio;Saito, Tohru;Itaya, Taisuke;Fujii, Tozo. And the article was included in Chemical & Pharmaceutical Bulletin in 1992.Computed Properties of C10H11BrO2 This article mentions the following:

Condensation of phenacyl bromide with amines gave PhCOCH₂NHCH₂R [R = 4-MeOC₆H₄, 3,4-(MeO)₂C₆H₃, 3,4-methylenedioxyphenyl] which were condensed with a chloropyrimidinone to give adducts I. Cyclization of I gave substituted guanine oxides II which were debenzylated to give the title compound (III). A series of alkyl and cycloalkyl substituted guanine oxides were prepared by the same methodol. All the substituted guanine oxides were tested for antileukemic activity and none were superior to III. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Computed Properties of C10H11BrO2).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Computed Properties of C10H11BrO2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

One-pot synthesis of α-bromoacetals of ketones from secondary alcohols and 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) in ethylene glycol was written by Han, Bingbing;Zheng, Zubiao;Wu, Fang;Wang, Aidong. And the article was included in Synthetic Communications in 2017.Related Products of 3418-21-1 This article mentions the following:

α-Bromoacetals of ketones were prepared from various secondary alcs. with 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) and ethylene glycol through oxidation, bromination, and acetalization in one pot without the use of other catalysts under mild conditions. The effects of DBDMH, the solvent, and N-bromosuccinimide on the reaction were investigated. Under the optimal conditions, most α-bromoacetals of ketones were obtain in 90-98% yields. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Related Products of 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Related Products of 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis 2-bromomethyl-2-aryl-1,3-dioxolanes – the precursors of adrenoceptor blockers was written by Vershinin, S. S.;Kotlov, V. M.;Klimakov, V. S.;Mindiyarova, E. R.;Zorin, V. V.. And the article was included in Bashkirskii Khimicheskii Zhurnal in 2011.Reference of 3418-21-1 This article mentions the following:

The effective method for preparation of 2-bromomethyl-2-R-1,3-dioxolanes I [R = Ph, 4-ClC₆H₄], the precursors of adrenoceptor blockers α and β, is developed. Intermediate 2-methyl-2-R-1,3-dioxolanes were obtained in high yields (up to 95%) via microwave-assisted heterocyclization of RC(O)Me with HOCH₂CH₂OH, which proceeds 12 times faster than heat-assisted reactions. Bromination of the resultant intermediates with mol. bromine selectively gave I [R = Ph, 4-ClC₆H₄] in 98 and 96% yields, resp. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1Reference of 3418-21-1).

2-(Bromomethyl)-2-phenyl-1,3-dioxolane (cas: 3418-21-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Reference of 3418-21-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem