Tag: 192.2112

The chemical and metabolite profiles of Gualou-Xiebai-Banxia decoction, a classical traditional Chinese medicine formula, by using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry and in-house software was written by Xiang, Zheng;Wang, Yuzhen;Liu, Shundi. And the article was included in Journal of Ethnopharmacology in 2022.Category: dioxole This article mentions the following:

Gualou-Xiebai-Banxia decoction (GXBD) was a classical traditional Chinese medicine formula for the treatment of coronary heart disease. However, the current study on the chem. and metabolite profiles of GXBD did not follow the ancient prescription and extraction method, which hindered the discovery of effective compounds and quality control. In this study, we prepared GXBD by ancient prescription and extraction methods, and then analyzed the chem. components and xenobiotics of GXBD in vivo using high-performance liquid chromatog. coupled with quadrupole time-of-flight mass spectrometry and inhouse software.49 chem. constituents were preliminarily identified, including 7 terpenoids, 6 flavonoids, 5 alkaloids, 17 organic acids, 8 steroids and steroidal saponins, 2 nucleosides and 4 other types of compounds, of which 10 constituents were confirmed unambiguously with authentic standards Moreover, 129 metabolites were tentatively identified, including 83 metabolites in plasma, 39 metabolites in urine, 25 metabolites in bile and 9 metabolites in feces. Our study speculated that luteolin, adenosine, vanillic acid and curbitacin B might be possible effective components of GXBD for the treatment of coronary heart disease. Dehydration, deglycosylation, dehydrogenation, acetylation and taurine regulation were the main biotransformation reactions of GXBD. Our results provided an important basis for the discovery of effective compounds and quality control of GXBD. In addition, inhouse software was an useful tool for identifcation of metabolites. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Category: dioxole).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Essential Oil of Deverra tortuosa Aerial Parts: Detailed Chemical Profile, Allelopathic, Antimicrobial, and Antioxidant Activities was written by Fayed, Eman M.;Abd-EIGawad, Ahmed M.;Elshamy, Abdelsamed I.;El-Halawany, El-Sayed F.;EI-Amier, Yasser A.. And the article was included in Chemistry & Biodiversity in 2021.Synthetic Route of C11H12O3 This article mentions the following:

Essential oils (EOs) are a promising group of natural products of the aromatic plants due to their various biol. effects such as allelopathic, antioxidant, antimicrobial activities. The present study aimed to construct the detailed chem. profile of the EO derived from Deverra tortuosa aerial parts along with assessing its allelopathic, antimicrobial, and antioxidant potentialities. The EO was extracted by hydrodistillation and analyzed via gas chromatog.-mass spectrometry (GC/MS). The allelopathic activity of the EO was assessed against the germination and seedling growth of the weed Chenopodium murale. Also, the EO was tested against five microbes. The antioxidant activity was determined using the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). The GC/MS anal. of EO revealed the presence of 86 compounds with a preponderance of oxygenated sesquiterpenes and monoterpene hydrocarbons. Widdrol, β-phellandrene, piperitol, cubedol, α-terpinene, (E)-10-heptadecen-8-ynoic acid Me ester, citronellyl tiglate, and m-cymene were the major compounds A comparative profile was established between the EOs constituents of our study with the documented EOs of D. tortuosa and the other Deverra species around the world via agglomerative hierarchical clustering (AHC) and principal components anal. (PCA). The EO showed a substantial allelopathic activity against C. murale, as well as it showed considerable antimicrobial and antioxidant activities. Thereby, the EO of D. tortuosa could be considered as a promising environmental-friendly bioherbicide against weeds. Also, it could be integrated into food preservation due to its potent antimicrobial and antioxidant activities. However, further study is recommended for more characterization of the major compounds and evaluation of their activities, either singular or synergistic, and assess their efficiency and biosafety. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Synthetic Route of C11H12O3).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Synthetic Route of C11H12O3

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Phytochemical components and biological activities of essential oils from three selected medicinal plants was written by Zhang, Lanyue;Ye, Mao;Shi, Yaohui;Zhu, Haiping;Chi, Lejing;Pan, Chunxing;Xu, Yani;Zheng, Xi;Xiang, Hongping;Li, Chunlian. And the article was included in Industrial Crops and Products in 2021.Application In Synthesis of 6-Allyl-4-methoxybenzo[d][1,3]dioxole This article mentions the following:

Essential oils extracted from herbs have been utilized in food and medicine on the account of their increasing physicochem. characteristics. This present study aimed to investigate the phytochem. components, anti-inflammatory, cytotoxic, anti-microbial and anti-oxidant activities of essential oils from Pogostemon cablin (P. cablin), Angelica dahurica (A. dahurica) and Myristica fragrans (M. fragrans), all belong to”medicine food homol. “herbs. Approx. 107 components were identified by gas chromatog. mass spectrometry (GC-MS) from these essential oils. The main compounds of P. cablin essential oils (PCEOs) were patchouli alc. (27.72%),α -buaiacene (17.94%) and α -guaiene (14.15%); in A. dahurica essential oils (ADEOs) were anethole (24.91%) and cinnamaldehyde (18.35%); and in M. fragrans essential oils (MFEOs) were (1S)-(-)-α -pinene (23.39%), α ;-terpineol (18.60%) and caryophyllene (10.34%). These essential oils were found to have strong anti-inflammatory activities through decreasing the production of cyclooxygenase-2 (COX-2), interleukin-6 (IL-6), nuclear factor-kappa B p65 (P65) and tumor necrosis factor-α (TNF-α). These essential oils also had significant anti-bacterial activities against both Gram-neg. and Gram-pos. strains and anti-fungal activities. Moreover, effective anti-oxidant properties of three essential oils were estimated (0.001962%-0.19%). The study also explored the effect of these essential oils on the survival of Brain microglia (BV2) microglial cells (IC₅₀ = 145.50-281.52μg/mL). Based on these bioactivities, these essential oils could be used as food additives, fragrances, cosmetics and health products. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Application In Synthesis of 6-Allyl-4-methoxybenzo[d][1,3]dioxole).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Application In Synthesis of 6-Allyl-4-methoxybenzo[d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

High Performance Liquid Chromatography versus Stacking-Micellar Electrokinetic Chromatography for the Determination of Potentially Toxic Alkenylbenzenes in Food Flavouring Ingredients was written by Dang, Huynh N. P.;Quirino, Joselito P.. And the article was included in Molecules in 2022.Name: 6-Allyl-4-methoxybenzo[d][1,3]dioxole This article mentions the following:

Alkenylbenzenes, including eugenol, methyleugenol, myristicin, safrole, and estragole, are potentially toxic phytochems., which are commonly found in foods. Occurrence data in foods depends on the quality of the anal. methodologies available. Here, we developed and compared modern reversed-phase high performance liquid chromatog. (HPLC) and stacking-micellar electrokinetic chromatog. (MEKC) methods for the determination of the above alkenylbenzenes in food flavouring ingredients. The anal. performance of HPLC was found better than the stacking-MEKC method. Compared to other HPLC methods found in the literature, our method was faster (total run time with conditioning of 15 min) and able to sep. more alkenylbenzenes. In addition, the anal. methodol. combining an optimized methanol extraction and proposed HPLC was then applied to actual food flavouring ingredients. This methodol. should be applicable to actual food samples, and thus will be vital to future studies in the determination of alkenylbenzenes in food. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Name: 6-Allyl-4-methoxybenzo[d][1,3]dioxole).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Name: 6-Allyl-4-methoxybenzo[d][1,3]dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

The effect of nutmeg essential oil constituents on Novikoff hepatoma cell viability and communication through Cx43 gap junctions was written by Mickus, Rokas;Janciuke, Gintare;Raskevicius, Vytautas;Mikalayeva, Valeryia;Matulyte, Inga;Marksa, Mindaugas;Maciunas, Kestutis;Bernatoniene, Jurga;Skeberdis, Vytenis Arvydas. And the article was included in Biomedicine & Pharmacotherapy in 2021.Category: dioxole This article mentions the following:

Essential oils from plants are a potential source of mols. having anti-inflammatory, anticancer, cardiotropic, and other activities. However, most of these effects lack mechanistic explanations and structure-activity relationship testing. In the present study, we: (1) identified the nutmeg essential oil (NEO) composition; (2) using mol. docking, we determined the putative regulatory binding sites on the connexin 43 (Cx43) that is responsible for gap junction-dependent intercellular communication (GJIC) in the majority of tissues; (3) examined the effect of NEO and its three constituents – sabinene, α-pinene, and α-copaene – on GJ conductance and gating in Novikoff cells expressing endogenous Cx43; and (4) verified whether NEO effects on GJIC correlated with its action on Novikoff cell viability, proliferation, and colony formation capability. Our results revealed NEO and its constituents as potent and efficient Cx43 GJ inhibitors acting by slow gating mechanism. In addition, NEO reduced Novikoff hepatoma cell viability, proliferation, and colony formation capability; however, this was achieved at higher doses and was unrelated to its effects on GJIC. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Category: dioxole).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Production of Marinated Chinese Lotus Root Slices Using High-Pressure Processing as an Alternative to Traditional Thermal-and-Soaking Procedure was written by Yuan, Lin;Xu, Feifei;Xu, Yingying;Wu, Jihong;Lao, Fei. And the article was included in Molecules in 2022.Product Details of 607-91-0 This article mentions the following:

Marinated vegetables are traditional cold dishes with a long history and special flavor in the Chinese deli market. However, the traditional thermal-and-soaking (TS) procedure often results in unreproducible flavor quality properties of marinated vegetables and waste of brine and time in production A novel green and sustainable technique, high-pressure processing (HPP), has caught the attention of the food industry. In this study, the effects of HPP and TS treatment on the visual, flavor, textural, and microbiol. qualities of Chinese marinated lotus root slices were investigated. Compared to the TS products, lighter color, more varieties of volatile compounds, and crunchier texture were detected in the HPP products. Throughout the 4°C, 25°C, and 45°C shelf life challenges, the HPP products retained their original color and crunchiness better than the TS ones, whereas no significant differences were found in total viable counts (TVCs) in the first half of the shelf lives. The Arrhenius model under the first-order reaction of TVC deterioration showed a good fit to the shelf life of the HPP marinated lotus root slices. This study demonstrates that HPP may assist in making the best use of brine in a more time-efficient manner to improve the visual, flavor, and textural quality of traditional Chinese marinated lotus root slices. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0Product Details of 607-91-0).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Product Details of 607-91-0

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Sedative effects of inhaled Perilla frutescens essential oils on mice was written by Ota, Yue;Ito, Michiho. And the article was included in Journal of Natural Medicines in 2021.SDS of cas: 607-91-0 This article mentions the following:

Perilla frutescens is an ingredient for cooking and for Japanese traditional medicine formulations. Essential oils extracted from P. frutescens are classified according to their composition, which are genetically regulated. Here, we extracted five types of essential oil from P. frutescens and studied their sedative activities. We grew P. frutescens strains that give oils of type PK, PA, PP, EK, and C, and extracted the essential oils by hydrodistillation We then measured the spontaneous locomotor activity of mice who had inhaled the oils in an open field test. All types of essential oil except the PK type decreased the spontaneous locomotor activity of mice. The EDs were 4.0 x 10-3 to 4.0 x 10-2 mg/cage (PA type), 4.0 x 10-4 mg/cage (PP type), 4.0 x 10-5 mg/cage (EK type), and 4.0 x 10-5 to 4.0 x 10-3 mg/cage (C type). Our results show that the essential oils of type PA, PP, EK, and C have a sedative effect. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0SDS of cas: 607-91-0).

6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.SDS of cas: 607-91-0

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem