Tag: 116.1583

Preparation of H₄SiW₁₂O₄₀ and its application in catalytic synthesis of ketal was written by Luo, Yumei;Lv, Yinhua;Liu, Jiangyan. And the article was included in Huaxue Yanjiu Yu Yingyong in 2005.Name: 2-Ethyl-2-methyl-1,3-dioxolane This article mentions the following:

A method for preparing catalyst H₄SiW₁₂O₄₀ was discussed. The catalytic activity of H₄SiW₁₂O₄₀ was validated in synthesizing cyclohexanone 1,2-propanediol ketal and the reaction conditions in synthesizing the other ketal (acetal) were also discussed. The yields of the other products were 85.5% for cyclohexanone 1,2-propanediol ketal, 89.6% for cyclohexanone ethylene ketal, 79.5% for butanone ethylene ketal, 89.1% for butyraldehyde ethylene acetal, and 81.5% for butyraldehyde 1,2-propanediol acetal. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Name: 2-Ethyl-2-methyl-1,3-dioxolane).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Name: 2-Ethyl-2-methyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

A simple approach to the preparation of H₆P₂W₁₈O₆₂/Cu₃(BTC)₂ (BTC = 1,3,5-benzenetricarboxylate) and its catalytic performance in the synthesis of acetals/ketals was written by Liu, Xiaoxia;Luo, Jing;Sun, Tingquan;Yang, Shuijin. And the article was included in Reaction Kinetics, Mechanisms and Catalysis in 2015.Synthetic Route of C6H12O2 This article mentions the following:

H₆P₂W₁₈O₆₂/Cu₃(BTC)₂ (BTC = 1,3,5-benzenetricarboxylate) as a new catalyst was prepared by the impregnation method and used to synthesize cyclohexanone ethylene ketal as a probe reaction, which has shown its favorable catalytic activity. FT-IR, XRD, SEM, N₂ adsorption-desorption isotherms and TG/DTA were used to characterize its composition, structure, morphol., stability and toleration for thermal in order to further prepare the catalyst with effective performance. Moreover, we have also explored the optimized conditions of carrying out the probe reaction by orthogonal experiments The optimized conditions were as follows: fixing cyclohexanone consumption was 0.02 mol, n(cyclohexanone):n(ethylene glycol) = 1:1.3, the mass ratio of the catalyst to total reactant was 0.2 %, cyclohexane dosage was 4 mL, and the reaction time was 75 min. The yield of the acetals and ketones could reach 54.9 ∼ 83.5 % under the optimum conditions. In addition, H₆P₂W₁₈O₆₂/Cu₃(BTC)₂ exhibited good reusability and the approaches above may enable rational design of advanced and environmental-friendly MOF-based catalysts. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Synthetic Route of C6H12O2).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C6H12O2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Control of the Dual Reactivity (Iminium-Dienamine) of β-Arylmethyl α,β-Unsaturated Aldehydes in Organocatalytic 1,3-Dipolar Cycloadditions with N-Benzoyl C,N-Cyclic Azomethine Imines was written by Izquierdo, Cristina;Esteban, Francisco;Parra, Alejandro;Alfaro, Ricardo;Aleman, Jose;Fraile, Alberto;Ruano, Jose Luis Garcia. And the article was included in Journal of Organic Chemistry in 2014.Name: 2-Ethyl-2-methyl-1,3-dioxolane This article mentions the following:

1,3-Dipolar cycloadditions of C,N-cyclic azomethine imines with α,β-unsaturated aldehydes can be performed with complete control of the regio-, exo-, and enantioselectivity under aminocatalytic conditions. The so far never studied competence of the iminium-dienamine reactivity inherent to β-alkyl α,β-unsaturated aldehydes was studied, which was possible by allowing achievement of complete control of the chemoselectivity in reactions of the β-arylmethyl derivatives with azomethine imines by using different additives and organocatalysts, whose role was rationalized by DFT calculations and chem. proofs. Thus, it was possible to selectively obtain the pyrazolidines resulting from both the attack to the C2-C3 (via iminium) and the C3-C4 (via dienamine) bonds at the starting enals, which can be used as precursors of interesting tetrahydroisoquinolinic compounds In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Name: 2-Ethyl-2-methyl-1,3-dioxolane).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Name: 2-Ethyl-2-methyl-1,3-dioxolane

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of acetals or ketals via acetalization or ketalization of aldehydes or ketones with glycols using titania-supported molybdotungstophosphoric acid (H₃Mo₆PW₆O₄₀) as catalyst was written by Yang, Shuijin;Tong, Wenlong. And the article was included in Xiyou Jinshu Cailiao Yu Gongcheng in 2007.Category: dioxole This article mentions the following:

A new environmentally friendly catalyst, H₃PW₆Mo₆O₄₀/TiO₂ is reported here. Optimized reaction conditions involved: mass ratio of m(TiO₂):m(H₃PW₆Mo₆O₄₀) 1/2.0, volume of water 30 mL, the reflux reaction time 2 h, activated temperature 150°. H₃PW₆Mo₆O₄₀/TiO₂ was used as catalyst in the synthesis of acetals and ketals, namely cyclohexanone ethylene ketal (i.e., 1,4-dioxaspiro[4.5]decane), cyclohexanone 1,2-propanediol ketal, butanone ethylene ketal, butanone 1,2-propanediol ketal, 2-phenyl-1,3-dioxolane, 4-methyl-2-phenyl-1,3-dioxolane, 2-propyl-1,3-dioxolane, 4-methyl-2-propyl-1,3-dioxolane. Effects of n(aldehyde/ketone):n(glycol), catalyst dosage and reaction time on yield were investigated. Optimized reaction conditions were: n(aldehyde/ketone):n(glycol) = 1.0:1.4; mass fraction of catalyst to reactants, 0.8%; reaction time, 1.0 h and cyclohexane as water-stripping reagent, 10 mL. Under these conditions, yield of cyclohexanone ethylene ketal, cyclohexanone 1,2-propanediol ketal, butanone ethylene ketal, butanone 1,2-propanediol ketal, 2-phenyl-1,3-dioxolane, 4-methyl-2-phenyl-1,3-dioxolane, 2-propyl-1,3-dioxolane and 4-methyl-2-propyl-1,3-dioxolane were 81.3%, 86.9%, 53.0%, 66.9%, 72.3%, 79.0%, 66.8%, 76.9% resp. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Category: dioxole).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation and catalytic activity of SO₄^2-/TiO₂-WO₃ was written by Yang, Shui-Jin;Bai, Ai-Min;Yu, Xie-Qing;Sun, Ju-Tang. And the article was included in Youji Huaxue in 2004.Formula: C6H12O2 This article mentions the following:

A novel solid superacid catalyst, SO₄^2-/TiO₂-WO₃, was prepared Its catalytic activity for twelve important ketals and acetals was measured with esterification of butyric acid with Bu alc. as probing reaction. The preparation conditions of SO₄^2-/TiO₂-WO₃ have also been investigated, i.e., the mass ratio of the H₂WO₄ used in the compound is 12.5%, the calcining temperature is 580°, the calcining time is 3 h, and the soaked consistency of H₂SO₄ is 1.0 mol/L^-1. Exptl. results showed that S0₄^2-/TiO₂-WO₃ is an excellent catalyst for the synthesis of twelve important ketals and acetals. The optimum reaction conditions are that the molar ratio of aldehyde/ketone to glycol is 1:1.5, the mass ratio of the catalyst used in the reactants is 0.5%, and the reaction time is 1.0 h. Under these conditions, the yield of 2-methyl-2-ethoxycarbonylmethyl-1,3-dioxolane is 78.7%, 2,4-dimethyl-2-ethoxycarbonylmethyl-1,3-dioxolane 83.0%, cyclohexanone ethylene ketal 85.9%, cyclohexanone 1,2-propanediol ketal 84.6%, butanone ethylene ketal 70.7%, butanone 1,2-propanediol ketal 88.3%, 2-propyl-1,3-dioxolane 80.6%, 4-methyl-2-propyl-1,3-dioxolane 79.6%, 2-isopropyl-1,3-dioxolane 64.2%, 4-methyl-2-isopropyl-1,3-dioxolane 83.3%, 2-phenyl-1,3-dioxolane 75.3%, 4-methyl-2-phenyl-1,3-dioxolane 95.1%, resp. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Formula: C6H12O2).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Formula: C6H12O2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Organocatalytic enantioselective conjugate addition of 2-nitrocyclohexanone to acrylaldehyde: a concise two-step synthesis of chiral building block 1-azaspiro[4.5]decan-6-one was written by Ding, Xiao-Hua;Cui, Wei-Chen;Li, Xiang;Ju, Xuan;Liu, Dan;Wang, Shaozhong;Yao, Zhu-Jun. And the article was included in Tetrahedron Letters in 2013.Recommanded Product: 126-39-6 This article mentions the following:

A gram-scale organocatalytic enantioselective Michael addition of α-nitrocyclohexanone to acrolein has been developed, and it was successfully applied to a concise two-step synthesis of (1S)-azaspiro[4.5]decan-6-one I, a useful chiral building block for the synthesis of a variety of natural alkaloids. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Recommanded Product: 126-39-6).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: 126-39-6

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of butanone ethylene ketal with SO₄^2-/TiO₂-La₂O₃ was written by Bai, Ai-min;Du, Xin-xian;Yang, Shui-jin. And the article was included in Huagong Keji in 2007.Recommanded Product: 126-39-6 This article mentions the following:

Butanone ethylene ketal was synthesized from butanone and ethylene glycol in the presence of SO₄^2-/TiO₂-La₂O₃. The factors influencing the synthetic process were discussed and the best conditions were found out. The optimum conditions are: molar ratio of butanone to ethylene glycol is 1:2.0, the quantity of catalyst is equal to 0.50% of feed stocks, the reaction temperature is 79-89°C, and the reaction time is 2.0 h. SO₄^2-/TiO₂-La₂O₃ is an excellent catalyst. For synthesizing butanone ethylene ketal and its yield can reach over 58.1%. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Recommanded Product: 126-39-6).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: 126-39-6

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis of (±)-Serralongamine A and the Revised Structure of Huperzine N was written by Saborit, Gisela V.;Bosch, Caroline;Parella, Teodor;Bradshaw, Ben;Bonjoch, Josep. And the article was included in Journal of Organic Chemistry in 2016.Synthetic Route of C6H12O2 This article mentions the following:

A revised structure for the Lycopodium alkaloid huperzine N,is proposed and confirmed by synthesis. The key synthetic steps involve an epimerization of a cis-5-oxodecahydroquinoline to the corresponding trans isomer and a coupling, followed by a diastereoselective hydrogenation using Wilkinson’s catalyst to incorporate the pyridylmethyl moiety. This route allowed the alkaloid serralongamine A, I, to be synthesized for the first time, and two addnl. steps led to the revised structure of huperzine N, II, both products bearing an unusual decahydroquinoline stereostructure. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Synthetic Route of C6H12O2).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Synthetic Route of C6H12O2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

The synthesis of ketal catalyzed with H₃PW₁₂O₄₀ supported onto active carbon was written by Gao, Jin-zhang;Wei, Yun-xia;Wang, Xue-mei;Guo, Hao;Yang, Wu. And the article was included in Xibei Shifan Daxue Xuebao, Ziran Kexueban in 2006.Computed Properties of C6H12O2 This article mentions the following:

The behavior of H₃PW₁₂O₄₀ supported onto active carbon (HPW/C) is studied. The catalytic activity for the formation of ketal by using 2-butanone and ethylene glycol is also studied. The target compound thus prepared was 2-ethyl-2-methyl-1,3-dioxolane (2-butanone ethylene ketal). The results show that the yield of ketal is up to 67.3% by using the proposed catalyst, which is higher than that of using the unique H₃PW₁₂O₄₀. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Computed Properties of C6H12O2).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Computed Properties of C6H12O2

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation of SO₄^2-/TiO₂-MoO₃ solid superacid and its catalytic activity in acetalation and ketalation was written by Yang, Shuijin;Liang, Yongguang;Yu, Xieqing;Sun, Jutang. And the article was included in Chinese Journal of Chemical Engineering in 2005.Recommanded Product: 126-39-6 This article mentions the following:

The SO₄^2-/TiO₂-MoO₃ solid superacid was prepared and its catalytic activity under different synthetic conditions was examined with esterification of n-butanoic acid and Bu alc. as probing reaction. Optimum conditions for catalyst preparation were determined, i.e., the mass ratio of MoO₃ is 25%, the calcination temperature 450°, and the soaked consistency of H₂SO₄ is 0.5 mol·L^-1. The superacid catalyst was evaluated in the preparation of six ketals and acetals. Under molar ratio of aldehyde/ketone to glycol 1:1.5, mass ratio of catalyst to reactants of 0.5%, and reaction time of 1.0 h, the yield of ketals and acetals was up to 63.2%. The catalyst can be easily recovered and reused. In the experiment, the researchers used many compounds, for example, 2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6Recommanded Product: 126-39-6).

2-Ethyl-2-methyl-1,3-dioxolane (cas: 126-39-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Recommanded Product: 126-39-6

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem