Tag: 100-200

Preparation of 12-tungstophosphoric acid/SBA-15 catalyst by in-situ method and its catalytic performance was written by Liu, Shi-rong;Guo, Hong-qi;Mao, Ming-fu;Ni, Zhong-bin;Chen, Ming-qing. And the article was included in Jingxi Huagong in 2013.Formula: C8H14O4 The following contents are mentioned in the article:

The catalysts of 12-tungstophosphoric acid/SBA-15 with different loading capacity were prepared by in-situ method. The structure and properties of the catalysts were characterized by means of FTIR spectroscopy, TEM, X-ray diffraction, ³¹PNMR and N₂ adsorption-desorption. The results showed that, when the loading capacity was within the lower range, the catalysts retained the long range order structure of the SBA-15 material. With the increase of loading capacity, the aperture and sp. surface area decreased with the increase of loading capacity. However, the structure of SBA-15 was destroyed in some degree when the loading capacity was up to 33.3%. The 12-tungstophosphoric acid highly dispersed in the hole of SBA-15 still kept the Keggin structure, and had certain chem. interaction with the surface hydroxy of SBA-15. The catalytic properties in the synthesis of fructone showed that HPW/SBA-15 catalyst had high catalytic activity and selectivity, and showed excellent reusability. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Formula: C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Formula: C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Characterization of supported heteropoly acid (salt) and its catalytic behavior in synthesis of fructone was written by Zhang, Fumin;Yuan, Chaoshu;Ren, Xiaoqian;Wang, Jun. And the article was included in Huagong Xuebao (Chinese Edition) in 2006.Safety of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:

A series of 12-phosphotungstic acid (PW) and its cesium salt catalysts immobilized on various supports such as ultra-stable Y zeolite (USY), dealuminated USY (DUSY), SiO₂ and SBA-15 were prepared Their sp. surface area and acid strength were measured, and their catalytic performance was evaluated in the synthesis of fructone by acetalization of Et acetoacetate with ethylene glycol. The high catalytic activity was found over the prepared supported heteropoly compound catalysts in this reaction. However, for the supported PW catalysts, a severe leaching of heteropoly anions into water was observed, leading to their poor reusability. By contrast, the Cs salt of PW catalyst supported on DUSY exhibited very high catalytic activity with high water tolerance and reusability. The conversion of Et acetoacetate of 98.7% with the selectivity of fructone above 97% could be obtained over 30% Cs_2.5H_0.5 PW/DUSY under the optimal reaction conditions. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Safety of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Safety of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Acetalization of ethyl acetoacetate with glycol over silica gel supported phosphotungstic acid catalyst was written by Yu, Qingyue;Zhou, Zhiwei;Wu, Wenliang;Yun, Zhi. And the article was included in Huaxue Fanying Gongcheng Yu Gongyi in 2009.Application In Synthesis of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:

A series catalysts of phosphotungstic acid (PW) supported on silica gel were prepared by sol-gel method and characterized by means of X-ray diffraction (XRD), low temperature adsorption and desorption of N₂, and temperature-programmed desorption of ammonia (NH₃-TPD). The catalytic performance was determined by acetalization of Et acetoacetate with glycol. The results showed that when the loading mass fraction of PW was 40%, PW was highly dispersed on silica gel, the pores were regular, the surface area was 187 m²/g and the acid amount was high, and the conversion of Et acetoacetate and the selectivity of fructone were 96.8% and 98.5%, resp., under the conditions of the molar ratio of Et acetoacetate to glycol 1:1.3, reaction temperature 353 K and reaction time 30 min. The stability tests showed that the conversion of Et acetoacetate and the selectivity of fructone were 93.1% and 98.0%, resp., after the catalyst was used 15 times. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Application In Synthesis of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Application In Synthesis of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Facile synthesis of fructone from ethyl acetoacetate and ethylene glycol catalyzed by SO₃H-functionalized Bronsted acidic ionic liquids was written by Liu, Yong;Wang, Yi-Tao;Liu, Tao;Tao, Duan-Jian. And the article was included in RSC Advances in 2014.Electric Literature of C8H14O4 The following contents are mentioned in the article:

SO₃H-functionalized Bronsted acidic ionic liquids (BAILs) were synthesized and utilized as highly efficient catalysts for the production of fructone via the acetalization reaction of Et acetoacetate with ethylene glycol. In comparison with conventional H₂SO₄ and cation exchange resins, the BAILs such as triethyl(4-sulfobutyl)ammonium hydrogen sulfate ([BSEt₃N][HSO₄]) of strong acidity exhibited excellent catalytic activity. The effects of various parameters such as different BAILs, reaction temperature, catalyst dosage, and molar ratio of the reactants on the conversion of Et acetoacetate were investigated in detail. The exptl. results indicated that the catalytic performance of BAILs were closely related to their Hammett acidities. Moreover, it was found that [BSEt₃N][HSO₄] could be also recovered easily and used repetitively six times without obvious decline in activity and quantity. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Electric Literature of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Electric Literature of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Preparation and testing of ceasium Bronsted ion-exchanged Al-SBA-15 supported heteropoly acid as heterogeneous catalyst in the fructone fragrancy synthesis was written by Tran, Quang Vinh;Truong, Thi Hanh;Hung, Tran Quang;Doan, Huan V.;Pham, Xuan Nui;Le, Nam Thi Hoai;Bach, Long Giang;Nguyen, Van Tuyen. And the article was included in Journal of Porous Materials in 2020.Safety of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:

Here we report a new ceasium Bronsted ion-exchanged Al-SBA-15 (Cs/AS15) supported heteropoly acid (HPA) H₃PW₁₂O₄₀ (HPA-Cs/AS15) material which can be prepared and used as heterogeneous catalyst for the fructone fragrancy synthesis. It was demonstrated that Cs⁺ was more effective than NH₄⁺ as counter cation of ion-exchanged AS15 support for preparing HPA/AS15 catalyst with higher acidity and HPA leaching stability. HPA-Cs/AS15 material showed high acidity with the maximum NH₃ desorption peak appeared at 759.6°C in the NH₃-TPD spectrum, stronger than pure HPA (635.7°C) and the ammonium Bronsted ion-exchanged Al-SBA-15 supported HPA (HPA-NH₄/AS15) (559.1°C) materials. The HPA leaching stability test showed that the HPA content of HPA-Cs/AS15 catalyst reduced only by 2.55% after five washing times, much less than that of HPA-NH₄/AS15 catalyst (49.22%). The higher acidity helped improve the HPA-Cs/AS15 catalyst performance in the fructone fragrancy synthesis. The Et acetoacetate conversion over this catalyst was 94.82%, better than those over HPA-NH₄/AS15 (93.49%) and pure HPA (89.52%) catalysts, although HPA-Cs/AS15 catalyst had lower HPA content (23.16 wt%) than HPA-NH₄/AS15 (24.28 wt%). In addition, it was shown that the reaction conditions such as Et acetoacetate:ethanediol reactant molar ratio of 1:1.5, ethanediol used as the diol reactant, and toluene used as the solvent, the fructone fragrancy synthesis reaction over HPA-Cs/AS15 catalyst reached the highest Et acetoacetate conversion (95.58%). The toluene’s boiling temperature of 110.6°C can promote the dispersion and contact abilities of the reactants with HPA mols. presented inside the pores of HPA-Cs/AS15 catalyst. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Safety of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Safety of Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Royal jelly may improve the metabolism of glucose and redox state of ovine oocytes matured in vitro and embryonic development following in vitro fertilization was written by Eshtiyaghi, Mahbobeh;Deldar, Hamid;Pirsaraei, Zarbakht Ansari;Shohreh, Bahram. And the article was included in Theriogenology in 2016.Application of 6413-10-1 The following contents are mentioned in the article:

The aim of this study was to investigate the effect of different concentrations of royal jelly (RJ) on in vitro maturation (IVM), fertilization, cleavage, blastocyst rates, glutathione (GSH) content in ovine oocyte, mRNA abundance of antioxidant enzymes in both oocyte and cumulus, and glucose metabolism-related genes in cumulus cells. In vitro maturation of oocyte was performed in the presence of control (RJ₀), 2.5 (RJ_2.5), 5 (RJ₅), and 10 (RJ₁₀) mg/mL of RJ. Nuclear status, intracellular GSH content in oocytes, and mRNA abundance of selected genes were evaluated following 24 h of IVM. Following the IVM, fertilization and embryo culture were carried out in all the groups and embryonic development was examined The addition of 10-mg/mL RJ to maturation media not only yielded a higher number of oocytes at MII stage but also showed an increased level of intracellular GSH content than did RJ_2.5 and control groups. Fertilization, cleavage, and blastocyst rate were higher in the RJ₁₀ treatment group in comparison to the control one. In cumulus cells, the expression of PFKM, PFKL, and G6PDH were increased following the addition of RJ to the maturation media. Supplementation of 10-mg/mL RJ to IVM medium increased the GPx mRNA abundance in both oocyte and cumulus cells and SOD expression in the cumulus cells. The CAT mRNA abundance was not influenced by the addition of RJ to the maturation media in either oocyte or cumulus cells. It seems that the improvement of oocyte maturation and its subsequent development in RJ₁₀ group may be associated with amelioration of redox status in the oocytes and activation of glucose metabolic pathways in their surrounding cumulus cells. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Application of 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Application of 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic synthesis of acetals and ketals with H₃PW₁₂O₄₀/PAn was written by Yang, Shuijin;Zhang, Yijun;Du, Xinxian;Merle, Philippe G.. And the article was included in Rare Metals (Beijing, China) in 2008.Category: dioxole The following contents are mentioned in the article:

A new environmental friendly catalyst H₃PW₁₂O₄₀/PAn (PAn = polyaniline) was prepared and identified by means of FT-IR, XRD, and TG/DTA. The optimum conditions have been found; i.e., the mass ratio of PAn to H₃PW₁₂O₄₀ is 1:1.5, the volume of methanol is 20 mL, and the reflux reaction time is 3 h. The structural identity of Keggin units is preserved after the incorporation into polyaniline matrix. Catalytic activities of H₃PW₁₂O₄₀/PAn in synthesizing 2-methyl-2-ethoxycarbonylmethyl-1,3-dioxolane, 2,4-dimethyl-2-ethoxycarbonylmethyl-1,3-dioxolane, cyclohexanone ethylene ketal, cyclohexanone 1,2-propanediol ketal, butanone ethylene ketal, butanone 1,2-propanediol ketal, 2-phenyl-1,3-dioxolane, 4-methyl-2-phenyl-1,3-dioxolane, 2-propyl-1,3-dioxolane, and 4-methyl-2-propyl-1,3-dioxolane were reported. It has been demonstrated that H₃PW₁₂O₄₀/PAn is an excellent catalyst. Various factors concerned in these reactions were investigated. The optimum conditions are as follows: the molar ratio of aldehyde/ketone to glycol (r) is 1:1.5, the mass ratio of the catalyst used to the reactants is 0.6%, and the reaction time is 1.0 h. Under these conditions, the yield is as follows: 2-methyl-2-ethoxycarbonylmethyl-1,3-dioxolane, 69.0%; 2,4-dimethyl-2-ethoxycarbonylmethyl-1,3-dioxolane, 79.5%; cyclohexanone ethylene ketal, 78.9%; cyclohexanone 1,2-propanediol ketal, 85.3%; butanone ethylene ketal, 56.9%; butanone 1,2-propanediol ketal, 78.1%; 2-phenyl-1,3-dioxolane, 76.3%; 4-methyl-2-phenyl-1,3-dioxolane, 94.2%; 2-propyl-1,3-dioxolane, 70.7%; and 4-methyl-2-propyl-1,3-dioxolane, 79.2%. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Category: dioxole).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Category: dioxole

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Synthesis, activity and mechanism for double-ring conjugated enones was written by Zhou, Shiyang;Huang, Gangliang;Chen, Guangying;Liu, Jian. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2021.SDS of cas: 6413-10-1 The following contents are mentioned in the article:

The relationship between TLR4 and inflammation-related diseases has been paid more and more attention. The studies have shown that TLR4/NF-κB signaling pathway plays an important role in the transmission of inflammatory signals. A large number of pro-inflammatory factors, chemokines, adhesion factors, TLR4 and its ligands interact with each other, and jointly promote the development of diseases. In this work, 8 target compounds were synthesized to screen the inhibitory activity of TLR4 in vitro. The TLR4 inhibition test in vitro showed that the double-ring conjugated enones had a good inhibitory activity, and the IC₅₀ value of compound 4f was 0.56 ± 0.10 μM, and it was superior to the pos. control methotrexate. To further study the anti-inflammatory effect and mechanism of double-ring conjugated enones by using LPS induced rat synovial cell inflammation model. The mechanism test showed that compound 4f could effectively promote the apoptosis of rat synovial cells, and the mechanism might be related to the up-regulation of the expression of apoptosis-related protein Caspase-3. In addition, compound 4f could significantly inhibit the increase of inflammatory factors TNF-α, IL-1β and IL-6 in rat synovial cells induced by LPS, showing a good anti-inflammatory activity. In the TLR4/NF-κB signaling pathway test of rat synovial cells, compound 4f can effectively regulate the expression levels of TLR4, MyD88, NF-κB and IκB related proteins in TLR4/NF-κB signaling pathway, which may be due to its inhibition of LPS-induced inflammation in rat synovial cells. At the same time, it inhibits the abnormal proliferation of cells and its important mechanism promoted of apoptosis. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1SDS of cas: 6413-10-1).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.SDS of cas: 6413-10-1

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Evaluation of in silico models for the identification of respiratory sensitizers was written by Dik, Sander;Ezendam, Janine;Cunningham, Albert R.;Carrasquer, Carl Alex;van Loveren, Henk;Rorije, Emiel. And the article was included in Toxicological Sciences in 2014.Name: Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate The following contents are mentioned in the article:

Low mol. weight (LMW) respiratory sensitizers can cause occupational asthma but due to a lack of adequate test methods, prospective identification of respiratory sensitizers is currently not possible. This article presents the evaluation of structure-activity relationship (SAR) models as potential methods to prospectively conclude on the sensitization potential of LMW chems. The predictive performance of the SARs calculated from their training sets was compared to their performance on a dataset of newly identified respiratory sensitizers and nonsensitizers, derived from literature. The predictivity of the available SARs for new substances was markedly lower than their published predictive performance. For that reason, no single SAR model can be considered sufficiently reliable to conclude on potential LMW respiratory sensitization properties of a substance. The individual applicability domains (ADs) of the models were analyzed for adequacies and deficiencies. Based on these findings, a tiered prediction approach is subsequently proposed. This approach combines the two SARs with the highest pos. and neg. predictivity taking into account model specific chem. AD issues. The tiered approach provided reliable predictions for one-third of the respiratory sensitizers and nonsensitizers of the external validation set compiled by the authors. For these chems., a pos. predictive value of 96% and a neg. predictive value of 89% were obtained. The tiered approach was not able to predict the other two-thirds of the chems., meaning that addnl. information is required and that there is an urgent need for other test methods, e.g., in chemico or in vitro, to reach a reliable conclusion. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Name: Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Name: Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem

Catalytic performance of phosphotungstic acid (salt) supported on SiO₂ for acetalization of ethyl acetoacetate with glycol was written by Zhang, Fumin;Yuan, Chaoshu;Wang, Jun. And the article was included in Shiyou Huagong in 2005.Computed Properties of C8H14O4 The following contents are mentioned in the article:

12-Phosphotungstic acid (PW₁₂) and/or its Cs salt and K salt supported on SiO₂ were prepared by impregnation at ambient temperature The salts thus prepared were cesium tungstophosphate (Cs_2.5H_0.5PW₁₂O₄₀) and potassium tungstophosphate (K_2.5H_0.5PW₁₂O₄₀). Their catalytic performances in synthesis of fructone (i.e., 2-methyl-1,3-dioxolane-2-acetic acid Et ester), by acetalization of Et acetoacetate with glycol were investigated. Their properties were characterized by means of X-ray diffraction (XRD), N₂ adsorption and Hammett indicator. The catalyst stability was evaluated by treatment with water, during which concentration of leached heteropoly acid or salt was measured by UV-visual spectrophotometer. The catalyst activity rose with increase of PW₁₂ (Cs – or K -salt) loading, and conversion of Et acetoacetate became steady when loading was more than 30%. For PW₁₂/SiO₂, Cs_2.5 H_0.5 PW₁₂/SiO₂ and K_2.5H_0.3 PW₁₂/SiO₂ catalysts, selectivity of fructone was 97%, and conversions of Et acetoacetate was 69.8%, 68.6% and 68.4%, resp. The treatment of catalysts with water showed that deactivation of catalyst related correspondingly with the amount of leached active heteropoly species, and stabilities of three catalysts were in the order of 30% Cs_2.5H_0.5 PW₁₂/SiO₂ 30% K_2.5H_0.5PW₁₂/SiO₂>>30% PW₁₂/SiO₂. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Computed Properties of C8H14O4).

Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Computed Properties of C8H14O4

Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem