So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.He, Zhi-Tao; Zhao, Yi-Shuang; Tian, Ping; Wang, Chuan-Chuan; Dong, Han-Qing; Lin, Guo-Qiang researched the compound: 5-(11bR)-Dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl-5H-dibenz[b,f]azepine( cas:1265884-98-7 ).Synthetic Route of C34H22NO2P.They published the article 《Copper-Catalyzed Asymmetric Hydroboration of α-Dehydroamino Acid Derivatives: Facile Synthesis of Chiral β-Hydroxy-α-amino Acids》 about this compound( cas:1265884-98-7 ) in Organic Letters. Keywords: dehydroamino acid preparation asym hydroboration copper catalyst; hydroxy amino acid asym preparation. We’ll tell you more about this compound (cas:1265884-98-7).
The Cu-catalyzed asym. conjugate hydroboration reaction of β-substituted α-dehydroamino acid derivatives has been established, affording enantio-enriched syn- and anti-β-boronate-α-amino acid derivatives with excellent combined yields (83-99%, dr ≈ 1:1) and excellent enantioselectivities (92-98% ee). The hydroboration products were expediently converted into valuable β-hydroxy-α-amino acid derivatives, which were widely used in the preparation of chiral drugs and bioactive mols.
As far as I know, this compound(1265884-98-7)Synthetic Route of C34H22NO2P can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem