On June 28, 2002, Poulsen, Carina Storm; Madsen, Robert published an article.Application of 38838-06-1 The title of the article was Carbohydrate Carbocyclization by a Zinc-Mediated Tandem Reaction and Ring-Closing Enyne Metathesis. And the article contained the following:
Me 5-deoxy-5-iodo-pentofuranosides are reductively ring-opened and propargylated in a tandem fashion in the presence of zinc. The 1,7-enynes thus obtained are subjected to ring-closing enyne metathesis with catalyst to produce functionalized 1-vinyl cyclohexenes. By adding BnNH2 to the tandem reaction, an amino group can be introduced in the 1,7-enyne products. Addition of 2-TMS-ethynylcerium(III) chloride after the reductive ring-opening produces the corresponding 1,6-enynes. Further annulation of the product 1,3-dienes can be achieved through a Diels-Alder reaction with good control of stereochem. These procedures constitute efficient methods for rapid carbocyclization and annulation of carbohydrates to produce a variety of functionalized five- and six-membered ring cyclitol systems, e.g. I. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Application of 38838-06-1
The Article related to zinc catalyst ring closure diels alder carbocyclization annulation deoxyiodopentofuranoside, ring opening deoxyiodopentofuranoside amino cyclitol preparation diels alder, amino cyclitol preparation diels alder carbocyclization annulation deoxyiodopentofuranoside and other aspects.Application of 38838-06-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem