Dioxole related

Msutu, Ath’enkosi published the artcileAcetals: a new organocatalysis chemotype for one-pot enantioselective α-amination, Name: 1,4-Dioxaspiro[4.5]decane, the publication is Tetrahedron Letters (2014), 55(14), 2295-2298, database is CAplus.

Conditions are described for one-pot Bronsted acid and organocatalyzed enantioselective α-amination of acetals and associated functionalities. Of the organocatalysts screened, proline tetrazole gave the highest ee, while aqueous monochloroacetic acid proved to be the best Bronsted acid activator regarding minimizing racemization and maximizing product yield. The reaction opens up the way for using masked carbonyl functionalities in organocatalysis.

Tetrahedron Letters published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Name: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Xu, Yu-lin published the artcileSynthesis of cyclohexanone ethylene ketal using H₃PW₁₂O₄₀/SiO₂ as catalyst, Formula: C8H14O2, the publication is Jingxi Huagong (2013), 30(6), 614-617, 655, database is CAplus.

A new environmental friendly catalyst, H₃PW₁₂O₄₀/SiO₂ was prepared by the sol-gel method, and characterized by means of FTIR and XRD. Cyclohexanone ethylene ketal was synthesized from cyclohexanone and ethylene glycol using H₃PW₁₂O₄₀/SiO₂ as catalyst. The influence factors on the yield of cyclohexanone ethylene ketal were also discussed. The optimum conditions were identified: molar ratio of cyclohexanone to ethylene glycol is 1:1.3, mass fraction of catalyst to reactants is 1.2%, cyclohexane dosage is 3 mL and reaction time is 45 min. The yield of cyclohexanone ethylene ketal can reach 89.7% under the optimum conditions.

Jingxi Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C13H10F2, Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Wang, Wen-lan published the artcileSynthesis of vanillin propylene glycol acetal over different molecular sieve catalysts, COA of Formula: C11H14O4, the publication is Huaxue Gongchengshi (2009), 23(4), 1-3, database is CAplus.

The vanillin 1,2-propylene glycol acetal was synthesized using vanillin and 1,2-propylene glycol as starting materials and HZSM-5, HY, H beta, HMCM-22, HMCM-41 different type mol. sieve as the catalyst. The catalysts were characterized by means of N₂ adsorption-desorption and FT-IR of adsorption pyridine. The results indicate that the HMCM-22 mol. sieve has the higher activity and the each kind of mol. sieve active order is: HMCM-22 > H beta > USY > HY > HZSM-5 > HMCM-41. The higher activity was due to the large secondary pore structure of HMCM-22 mol. sieve and the suitable acidity.

Huaxue Gongchengshi published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C17H29BO2, COA of Formula: C11H14O4.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Li, Ming published the artcileA study on the cataluminescence of propylene oxide on FeNi layered double hydroxides/graphene oxide, COA of Formula: C6H12O2, the publication is New Journal of Chemistry (2021), 45(26), 11823-11830, database is CAplus.

In this work, FeNi layered double hydroxides/graphene oxide (FeNi LDH/GO) was prepared, which exhibits excellent selective cataluminescent performance towards propylene oxide. The selectivity and sensitivity of the cataluminescence (CTL) reaction were investigated in detail. Moreover, the catalytic reaction mechanism, including the intermediate products and the conversion of reactants to products, was discussed based on both the exptl. and computational results. Furthermore, the proposed FeNi LDH/GO based CTL sensor was successfully applied for the determination of propylene oxide residue in fumigated raisins, which indicates extensive application potential for rapid food safety evaluation.

New Journal of Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, COA of Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Du, Bin published the artcileStudy on catalytic synthesis of ethylene glycol cyclohexanone ketal by ferric solid superacid, Recommanded Product: 1,4-Dioxaspiro[4.5]decane, the publication is Liaoning Huagong (2012), 41(11), 1133-1135, database is CAplus.

Cyclohexanone ethylene glycol ketal was synthesized from cyclohexanone and ethylene glycol by using ferric solid superacid as the catalyst and cyclohexane as the water-carrying agent. The experiment results show that the ferric solid superacid has high activity and good stability; optimal synthesis conditions are as follows: molar ratio of cyclohexanone to ethylene glycol is 1:14, mass ratio of cyclohexanone to the catalyst is 32.8:1, volume ratio of cyclohexanone to cyclohexane is 2.08:1, and reaction time is 1 h. Under above conditions, the yield of cyclohexanone ethylene glycol ketal is over 86%.

Liaoning Huagong published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Recommanded Product: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Qian, Deyun published the artcileGold(I)-catalyzed highly diastereo- and enantioselective alkyne oxidation/cyclopropanation of 1,6-enynes, Application of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Angewandte Chemie, International Edition (2014), 53(50), 13751-13755, database is CAplus and MEDLINE.

A highly enantioselective oxidative cyclopropanation of 1,6-enynes catalyzed by cationic Au^I/chiral phosphoramidite complexes was presented. The new method provided convenient access to densely functionalized bicyclo[3.1.0]hexanes bearing three contiguous quaternary and tertiary stereogenic centers with high enantioselectivity (up to e.r. 98:2). Control experiments suggested that the quinoline moiety of the β-gold vinyloxyquinolinium intermediate in the reaction played an important role in promoting good enantioselectivity through a transitional auxiliary effect in the transition state.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Application of (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kikuchi, Hiroto published the artcileActivity of host-derived attractants and their related compounds toward the zoospores of phytopathogenic Aphanomyces cochlioides, Computed Properties of 110204-45-0, the publication is Bioscience, Biotechnology, and Biochemistry (1995), 59(11), 2033-5, database is CAplus.

Eleven flavones, including cochliophilin A and a chromone, were chem. prepared to determine the attracting activity for zoospores of Aphanomyces cochlioides, a causative fungus of spinach root rot. Analyses of the structure-activity relationship of each revealed a significant correlation between the zoospore attracting activity and the A-ring oxygenation at C-5 and C-7 in flavone skeleton. The relative attractancy of 4 regioisomers of N-trans-feruloyl 4-O-methyldopamine, which was identified as a zoospore attractant specific to another host plant Chenopodium album, was also examined

Bioscience, Biotechnology, and Biochemistry published new progress about 110204-45-0. 110204-45-0 belongs to dioxole, auxiliary class Flavonoids, name is 9-Hydroxy-6-phenyl-8H-[1,3]dioxolo[4,5-g]chromen-8-one, and the molecular formula is C16H10O5, Computed Properties of 110204-45-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Zieba, Andrzej published the artcilePalladium-Catalysed Carboborylation for the Synthesis of Borylated Indanes, Synthetic Route of 503538-69-0, the publication is European Journal of Organic Chemistry (2021), 2021(29), 4072-4075, database is CAplus.

A palladium-catalyzed carboborylation reaction for the synthesis of borylated indanes has been investigated. This reaction proceeds in good yields with an achiral catalyst, and is tolerant of substitution on the aryl ring, although sensitivity to the substitution of the alkene was observed Initial studies towards an enantioselective version of this reaction were undertaken, identifying phosphoramidites as a promising ligand class. This allowed for the synthesis of chiral indane and indolone products with moderate levels of enantioselectivity.

European Journal of Organic Chemistry published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C10H14O, Synthetic Route of 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Yang, Zhiwang published the artcilePreparation and application of SO₄^2-/SnO₂/SBA-15 solid acid catalyst for acetalization of cyclic ketones, Synthetic Route of 177-10-6, the publication is Cuihua Xuebao (2012), 33(5), 827-832, database is CAplus.

SO₄^2-/SnO₂/SBA-15 catalyst samples with different amounts of SnO₂ were prepared by a wetness impregnation method and characterized by X-ray diffraction, N₂ adsorption-desorption, and transmission electron microscopy. Their catalytic performance for the acetalization of 4-tert-butylcyclohexanone with glycol was investigated. The results showed that SBA-15 supported SO₄^2-/SnO₂ improved the catalytic activity markedly, which was caused by the increasing surface area of the sulfated tin oxide. The catalytic performance of SO₄^2-/20%SnO₂/SBA-15 for acetalization of several cyclic ketones with diols was also explored. Under the optimum conditions, a series of cyclic ketones such as cyclohexanone, 4-methylcyclohexanone, and 4-tert-butylcyclohexanone were well transformed into the corresponding products. The catalyst can be reused for several times without any significant loss in catalytic activity.

Cuihua Xuebao published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C17H18N2O6, Synthetic Route of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Hu, Jian published the artcilePalladium-Catalyzed Asymmetric Intermolecular Cyclization, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Angewandte Chemie, International Edition (2013), 52(33), 8676-8680, database is CAplus and MEDLINE.

The palladium(II)-catalyzed domino Heck cyclization reactions of o-vinylaryl triflates with cyclic alkenes to give polycyclic products, e.g., I, with high enantioselectivity was reported. The methodol. was applied to a short synthesis of diamine II, a precursor of (-)-martinellic acid.

Angewandte Chemie, International Edition published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem