Dioxole related

Tan, Xin published the artcileThree-Dimensional Phosphine Metal-Organic Frameworks Assembled from Cu(I) and Pyridyl Diphosphine, COA of Formula: C8H14O2, the publication is Chemistry of Materials (2012), 24(3), 480-485, database is CAplus.

Metal-organic frameworks (MOFs) with phosphine based ligands are extremely attractive for catalysis. Phosphine was successfully incorporated for the first time into three-dimensional (3D) MOFs. The MOFs are based on rigid L₂M₂ dimeric secondary building blocks assembled from Cu(I) and a pyridyl diphosphine ligand, 4-(3,5-bis(diphenylphosphino)phenyl)pyridine, with Br^– (CuL-Br), Cl^– (CuL-Br), or PF₆^– (CuL-PF₆) as counteranions [L = 4-(3,5-bis(diphenylphosphino)phenyl)pyridine]. The structures have a 4.12² net topol., which can be further simplified to 6⁴.8²-qtz. The MOFs contain 1D homochiral channels. The PF₆^– anions hosted in the 1D channel of CuL-PF₆ can be readily exchanged with Br^– or Cl^– while keeping the framework intact. The materials show anion-tunable flexible porosity. CuL-Br reveals gradual uptake of MeOH, while CuL-PF₆ exhibits stepwise sorption for MeOH. The heterogeneous Lewis acid catalytic activity of the MOFs was shown in ketalization reaction. CuL-Br and CuL-PF₆ are active in the reactions between ethylene glycol and 2-butanone/cyclohexanone, up to 93% yield with 0.2 mol % catalyst loading. In contrast, no reaction happens between ethylene glycol and bulky benzophenone, suggesting profound size selectivity. The catalysts can be reused with the framework left intact for three runs without loss of activity.

Chemistry of Materials published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C16H20N2, COA of Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Hurley, Scott published the artcileEffects of impregnated metal ions on air/CO₂-gasification of woody biomass, Safety of 2,2,4-Trimethyl-1,3-dioxolane, the publication is Bioresource Technology (2010), 101(23), 9301-9307, database is CAplus and MEDLINE.

Several impregnated metal ions (Fe (III), Co (II), Ni (II), and Ru (IV)) and a raw iron ore (natural limonite) were examined as catalysts for gasification of pine sawdust in air/CO₂ at 700 and 800°. The yields of char and tar both increased with increasing CO₂ content in the feed gas. All the impregnated metal ions, in particular Ni (II), Co (II) and Ru (IV), were very effective for promoting biomass gasification in CO₂, leading to greatly reduced yields of tar and char accompanied by significantly enhanced formation of CO and H₂. At 800°, the impregnation of Fe (III), Ni (II), Co (II) or Ru (IV) led to almost complete conversion of the solid biomass into gas/liquid products, producing an extremely low char yield ( < 1-4%), and a very high yield of combustible gas (from 51.7% for Fe to 84% for Ru). The tar yield reduced from 32.1% without catalyst to 19-27% with the impregnated metal ions.

Bioresource Technology published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Safety of 2,2,4-Trimethyl-1,3-dioxolane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Bonner, Trevor G. published the artcileOpening of cyclic acetals by trichloro-, dichloro-, and tribromoborane, HPLC of Formula: 1193-11-9, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1981), 1807-10, database is CAplus.

Reaction of cyclic acetals with BCl₃ gave α-chloro ethers which on in situ LiAlH₄ reduction gave hydroxy ethers in 49-99% yield. E.g., treatment of 2-propyl-1,3-dioxolane with BCl₃ (CH₂Cl₂, ∼0°, 0.2 h) followed by LiAlH₄ (Et₂O, 30 min) gave >95% HO(CH₂)₂OBu. The rate determining step in this reaction is the formation of an intermediate oxocarbenium ion. BBr₃ was a more, and BHCl₂ a less, powerful reagent than BCl₃ for this reaction.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, HPLC of Formula: 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Jung, Jong-Min published the artcileControl of the fate of toxic pollutants from catalytic pyrolysis of polyurethane by oxidation using CO₂, COA of Formula: C6H12O2, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2022), 442(Part_1), 136358, database is CAplus.

In automotive industry, plastic consumption has substantially increased due to its affordability, durability, and lightness. However, the massive generation of plastic wastes from the automotive industry becomes a growing environmental concern. Current disposal methods of end-of-life vehicles (ELVs) are incineration and landfilling, but these methods generate toxic chems. and leachate into the environment. To propose more sustainable disposal platform for ELVs, this study used a pyrolysis process using CO₂ as a reaction medium. As a case study, automotive seat form (ASF) in ELVs was disposed and valorized through the CO₂-assisted pyrolysis. ASF, composed of polyurethane, generated harmful aromatic compounds during pyrolysis process such as benzene, aniline and their derivatives To convert harmful chems. into value-added syngas (H₂ and CO), catalytic pyrolysis of ASF was performed using a nickel catalyst. Effects of both CO₂ and nickel catalyst showed 89.9 wt% reduction of toxic chem. production by converting them into syngas, as comparing to pyrolysis without Ni catalyst. Gas-phase-reaction between CO₂ and pyrogenic products from ASF resulted in more than 200 times of CO production Also, CO₂ suppressed catalyst deactivation. Therefore, this study suggested that CO₂ and plastic waste from ELVs can be converted to value-added products through CO₂-assisted catalytic pyrolysis.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, COA of Formula: C6H12O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Kim, Sung Phil published the artcileElm tree (Ulmus parvifolia) bark bioprocessed with mycelia of shiitake (Lentinus edodes) mushrooms in liquid culture: Composition and mechanism of protection against allergic asthma in mice, Recommanded Product: 1,4-Dioxaspiro[4.5]decane, the publication is Journal of Agricultural and Food Chemistry (2016), 64(4), 773-784, database is CAplus and MEDLINE.

Mushrooms can break down complex plant materials into smaller, more digestible and bioactive compounds The present study investigated the antiasthma effect of an Ulmus parvifolia bark extract bioprocessed in Lentinus edodes liquid mycelium culture (BPUBE) against allergic asthma in chicken egg ovalbumin (OVA)-sensitized/challenged mice. BPUBE suppressed total IgE release from U266B1 cells in a dose-dependent manner without cytotoxicity. Inhibitory activity of BPUBE against OVA-specific IgE secretion in bronchoalveolar lavage fluid (BALF) was observed in OVA-sensitized/challenged asthmatic mice. BPUBE also inhibited OVA-specific IgG and IgG1 secretion into serum from the allergic mice, suggesting the restoration of a Th2-biased immune reaction to a Th1/Th2-balanced status, as indicated by the Th1/Th2 as well as regulatory T cell (Treg) cytokine profile changes caused by BPUBE in serum or BALF. Inflammatory cell counts in BALF and lung histol. showed that leukocytosis and eosinophilia induced by OVA-sensitization/challenge were inhibited by the oral administration of BPUBE. Amelioration of eosinophil infiltration near the trachea was associated with reduced eotaxin and vascular cell adhesion mol.-1 (VCAM-1) levels. Changes in proinflammatory mediator levels in BALF suggest that BPUBE decreased OVA-sensitization-induced elevation of leukotriene C₄ (LTC₄) and prostaglandin D₂ (PGD₂). The finding that asthma-associated biomarker levels of OVA-sensitized/challenged mice were much more inhibited with BPUBE treatment than NPUBE (not-bioprocessed Ulmus parvifolia extract) treatment suggested the production of new bioactive compounds by the mushroom mycelia that may be involved in enhancing the observed antiasthmatic properties. The possible relation of the composition determined by proximate anal. and GC/MS to observed bioactivity is discussed. The results suggest that the elm tree (Ulmus parvifolia) bark bioprocessed with mycelia of shiitake (Lentinus edodes) mushrooms has the potential to prevent and/or treat allergic asthma.

Journal of Agricultural and Food Chemistry published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Recommanded Product: 1,4-Dioxaspiro[4.5]decane.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Tolstoy, Paivi published the artcileSynthesis of Enantiomerically Enriched 3-Amino-2-oxindoles through a Palladium-Mediated Asymmetric Intramolecular Arylation of α-Ketimino Amides, HPLC of Formula: 503538-69-0, the publication is Organic Letters (2012), 14(18), 4810-4813, database is CAplus and MEDLINE.

A highly efficient and enantioselective synthesis of 3-amino-2-oxindoles through a palladium-catalyzed asym. intramol. arylation of α-ketimino amides using (R)-DiFluorPhos as the coordinating ligand is reported. This report constitutes the first enantioselective palladium-catalyzed arylation of ketimines.

Organic Letters published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C15H21BO4, HPLC of Formula: 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Mastagli, Pierre published the artcileComparison of molybdic anhydride, titanium tetrachloride, stannic chloride, and aluminum chloride as catalysts in the synthesis of dioxanes and dioxolanes, Related Products of dioxole, the publication is Compt. Rend. (1962), 2978-80, database is CAplus.

Ethylene glycol, propylene glycol, and 1,3-butanediol are treated with aldehydes and ketones in the presence of TiCl₄ and the glycols are also treated with cyclohexanone in the presence of SnCl₄, AlCl₃, and MoO₃ to give 1,3-dioxolanes, 1,3-dioxanes, and dioxaspiro compounds TiCl₄ (2 ml.) and 1 mole diol are heated, 2/3 mole carbonyl compound is added slowly, the mixture is kept for 24 hrs., the product is decanted from unreacted diol, and washed with carbonated H₂O. The product is then taken up in C₆H₆, the C₆H₆ solution dried, and the C₆H₆ is distilled from the solution as part of the azeotrope. The carbonyl compounds are PrCHO, BzH, and Me₂CO. Prepared in this manner are I (R, R’, R”, b.p., n_D, % yield given): Pr, H, H, 132°, n^22.6_D 1.4332, 90; Ph, H, H, b₂₅ 129°, n²⁰_D 1.533, 80°; Me, Me, H, 92°, n¹⁸_D 1.4001, 51; Pr, H, Me, 141-4°, n^17.4_D 1.4123, 90°; Ph, H, Me, b₁₂ 128°, n^22.6_D 1.5165, 80; Me, Me, Me, 97-9°, n^16.6_D 1.4038, 53. Also prepared are II (same data given): Pr, H, Me, 159-61°, n^17.6_D 1.4246, 83; Ph, H, Me, b₂₀ 140°, n²²_D 1.5149, 92°; Me, Me, Me, 131°, n^16.4_D 1.4203, 42. The diols are treated with cyclohexanone in the presence of MoO₃, TiCl₄, SnCl₄, and AlCl₃ to yield the following compounds [b.p., n_D, % yield with MoO₃, TiCl₄, SnCl₄, and AlCl₃ given]: 1,4-dioxaspiro[4.5]decane, 176-80°, n^20.6_D 1.4581, 43, 76, 76, 75; 2-methyl-1,4-dioxaspiro[4.5]decane, 182-6°, n²⁰_D° 1.4518, 55, 85, 77, 76; 2-methyl-1,5-dioxaspiro[5.5]undecane, 205-8°, n²³_D 1.4582, 20.5, 75, 70, 70.

Compt. Rend. published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Related Products of dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Chan, Sau Hing published the artcileAsymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems, Computed Properties of 503538-69-0, the publication is Tetrahedron: Asymmetry (2007), 18(22), 2625-2631, database is CAplus.

The iridium complex-catalyzed asym. hydrogenation of quinolines in a poly(ethylene glycol) di-Me ether (DMPEG)/hexane biphasic system was studied. Catalysts with C₂-sym. ligands such as Xyl-P-Phos, Cl-MeO-BIPHEP, SYNPHOS, and DifluorPhos are highly effective for this type of reaction. Most of the catalysts tested can be retained in DMPEG (M_n = 500), and the asym. hydrogenation of various quinoline substrates can be carried out in DMPEG/hexane biphasic system with up to 92% ee. The catalysts and the products can be separated via simple phase separation, and the reactivity/stereoselectivity of the catalysts can be retained for at least three reaction cycles.

Tetrahedron: Asymmetry published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Computed Properties of 503538-69-0.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Burns, Alan R. published the artcileEnantioselective, rhodium-catalyzed 1,4-addition of organoboron reagents to electron-deficient alkenes, Formula: C38H24F4O4P2, the publication is Organic Reactions (Hoboken, NJ, United States) (2017), 1-686, database is CAplus.

A review. The enantioselective 1,4-addition of organometallic reagents to electron-deficient alkenes is one of the most important methods for carbon-carbon bond formation. Within this field, the rhodium-catalyzed 1,4-addition of organoboron reagents to electron-deficient alkenes occupies a prominent position owing to (1) the availability, stability, and functional group tolerance of organoboron reagents, (2) the wide range of acceptors that may be employed, (3) the ability of a broad range of structurally distinct families of chiral ligands to induce high enantioselectivities in the reactions, and (4) the usually mild and exptl. convenient conditions, which generally do not require any special precautions to exclude air or moisture.

Organic Reactions (Hoboken, NJ, United States) published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Formula: C38H24F4O4P2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Lee, Joon-Bae published the artcileThe comparison of derivatization methods for the determination of ethylene glycol in lubricant oil sample by GC/MS, Application In Synthesis of 177-10-6, the publication is Bulletin of the Korean Chemical Society (2012), 33(12), 4243-4246, database is CAplus.

The study evaluates several derivatization methods for the determination of ethylene glycol (EG) in lubricant oil with GC/MS. EG was derivatized with bistrimethylsilyltrifluoroacetamide (BSTFA), 1-butylboronic acid and cyclohexanone, and then compared with each other’s results. The optimized anal. procedure for EG in lube oil samples with GC/MS including extraction and derivatization is presented. For the anal. of alcs. by GC/MS, BSTFA is the widely used reagent for trimethylsilylization (TMS) derivatization.

Bulletin of the Korean Chemical Society published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Application In Synthesis of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem