Dioxole related

Krutskii, L. N. published the artcileReaction of 2-chloro-1,3,2-dioxaphospholanes and -phosphorinanes with 1,3-dioxacyclanes, Category: dioxole, the publication is Zhurnal Obshchei Khimii (1983), 53(7), 1525-32, database is CAplus.

The title reaction proceeds primarily via rearrangement of the intermediately formed spiro phosphorus salts, e.g. I (from II and III) and cleavage of the 1,3,2-dioxaphosphacyclane ring to give products, e.g. IV. Reaction of V (R¹ = Me, Et, CH₂Cl; R² = H, CH₂Cl) with ClCH₂OR³ (R³ = Pr, Bu) gave [Cl(CH₂)₃O](R¹R²CHO)P(O)CH₂OR³.

Zhurnal Obshchei Khimii published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Category: dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Patel, Rajani published the artcileGas chromatography-mass spectrometry analysis of chemical components of two different stages of root part of moolak (Raphanus sativus Linn.), SDS of cas: 177-10-6, the publication is International Journal of Research in Ayurveda & Pharmacy (2021), 12(2), 11-14, database is CAplus.

Moolak or Radish (Raphanus sativus Linn.) is grown all over the world. Radish is eaten raw as salad due to its pungent flavor. Tender radish root is consumed with leafy vegetable and radish in its starting stage of bolting is consumed as stew. After late bolting stage, only new leaves produced in inflorescence axis and seeds are consumed as edible substance and mature seeds are used for medicinal purpose like Kushtha (Skin disease). Formulations of Moolak seed is already mentioned in Ayurvedic literatures. Here we are taking tender and early bolt stage of radish where tender is balmoolak and Bolt is vriddha moolak. This study shows the differences in chem. composition of two stages of moolak to know about their medicinal properties, because medicinal properties of herbs are due to phytoconstituents. GC-MS (Gas chromatog.-mass spectrometry) technique is used to identify bioactive compounds in methanolic extract of Raphanus sativus. Tender radish (balmoolak) has shown total 38 peaks and Bolt radish (vriddhamoolak) showed total 41 peaks of phytoconstituents. 15 compounds are common among both samples.

International Journal of Research in Ayurveda & Pharmacy published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, SDS of cas: 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Deng, Gui-sheng published the artcileAcetalization of carbonyl compounds with diols catalyzed by InCl₃.4H₂O, Formula: C8H14O2, the publication is Hunan Shifan Daxue Ziran Kexue Xuebao (2012), 35(4), 35-39, database is CAplus.

Acetalization of aromatic and aliphatic aldehydes with diols catalyzed by InCl₃.4H₂O was carried out in refluxing benzene to give the corresponding acetals in 76%-85% yields. And ketone acetals were obtained in 75%-82% yields in the same method.

Hunan Shifan Daxue Ziran Kexue Xuebao published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C8H14O2, Formula: C8H14O2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Artz, William E. published the artcileVolatiles in a fat-based fat substitute model compound, esterified propoxylated glycerol soyate, Synthetic Route of 1193-11-9, the publication is Journal of Food Lipids (2001), 8(3), 191-204, database is CAplus.

Static headspace and GC/IR-MS (capillary gas-liquid chromatog., with an IR detector and a mass spectrometer), were used to collect, sep., identify, and quantitate the volatile products in the EPG-08 soyate sample, (esterified propoxylated glycerol, which is a model fat substitute compound with 8 mol of propylene oxide per mol. of glycerol), EPG-00 soyate (essentially trans-esterified soybean oil with no added propylene oxide), and a 50:50 (volume:volume) mixture of the 2 oil samples. Each sample was heated at ∼192 °C for 12 h/day until the oil contained ≥20% triacylglycerol polymer. The EPG-08 soyate samples were heated for 36 h, whereas the EPG-00 soyate and the 50:50 mix samples were heated for 48 h^–. The major volatile decomposition products found included hexanal, heptanals, trans-2-heptenal, trans-2-octenal, and trans,trans-2,4-decadienal. All of the volatiles detected in the oil samples were found previously in heated soybean oil, with the exception of 2,2,4-trimethyl-1,3-dioxolane, 2-ethyl-4-methyl-1,4-dioxolane, and acetoxy-acetone found in the EPG-08 soyate samples. The presence of many of the volatiles found with headspace anal., were confirmed using solid phase microextraction-GC/IR-MS.

Journal of Food Lipids published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Synthetic Route of 1193-11-9.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Eliel, Ernest L. published the artcileCarbon-13 NMR spectra of saturated heterocycles. VIII. Tetrahydrofurans and 1,3-dioxolanes, Related Products of dioxole, the publication is Organic Magnetic Resonance (1979), 12(8), 461-6, database is CAplus.

¹³C NMR spectra were obtained for 17 Me- and Et-substituted tetrahydrofurans and 58 alkyl- and aryl-substituted 1,3-dioxolanes. Additive substituent parameters calculated for compounds containing recurring substituents were compared with similar parameters in cyclopentanes and 6-membered rings. The additivity of the parameters is good considering the conformational flexibility of 5-membered ring systems.

Organic Magnetic Resonance published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Related Products of dioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Gan, Wangbao published the artcileSynthesis of vanillin propylene glycol acetal by microwave irradiation and its application in flavors, HPLC of Formula: 68527-74-2, the publication is Xiangliao Xiangjing Huazhuangpin (2008), 1-3, database is CAplus.

Vanillin propylene glycol acetal was synthesized under microwave irradiation from vanillin and 1,2-propylene glycol in the presence of citric acid. The factors that influenced the reaction under microwave heating were investigated, the yield of 41.04% was obtained under conditions of 1,2-propylene glycol_vanillin=1.2:1 (mol/mol), citric acid 2 g/mol (based on the amount of vanillin), irradiation power 600W, time 12 min. Its application in baked food was tested.

Xiangliao Xiangjing Huazhuangpin published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C11H14O4, HPLC of Formula: 68527-74-2.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Teng, Jun-jiang published the artcileCatalytic synthesis of cyclohexanone ethylene ketal by polyaniline doped with sodium hydrogen sulfate, Quality Control of 177-10-6, the publication is Riyong Huaxue Gongye (2012), 42(3), 209-212, database is CAplus.

Cyclohexanone ethylene ketal was synthesized from cyclohexanone and ethylene glycol as starting materials using polyaniline (PAn) doped with 20% (mass fraction) of sodium hydrogen sulfate (PAn-NaHSO₄) as catalyst. Catalytic activity of PAn-NaHSO₄ was investigated. Effect of factors such as mole ratio of ethylene glycol to cyclohexanone, dosage of the catalyst, reaction time, dosage of water stripping agent on product yield were examined systematically and optimum reaction conditions were identified by orthogonal designed experiment Under optimal conditions: based on amount of cyclohexanone 0.1 mol, mole ratio n(ethylene glycol): n(cyclohexanone) = 1.6:1, mass fraction of PAn-NaHSO₄ 1.2% of the total reactants, water stripping agent cyclohexane 9 mL and reaction time 2.5 h, yield of the product achieves 96.79%. The product was identified as cyclohexanone ethylene ketal by IR and GC-MS. Purity of product achieves 99.0%. After reusing the catalyst for 5 times, yield of the product is still higher than 90.0%.

Riyong Huaxue Gongye published new progress about 177-10-6. 177-10-6 belongs to dioxole, auxiliary class Dioxolane,Spiro, name is 1,4-Dioxaspiro[4.5]decane, and the molecular formula is C17H14N2O2, Quality Control of 177-10-6.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Susanti, Nora published the artcileIncreased stability of Styrax benzoin extract and fraction with the addition of Cosolvents, Application of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, the publication is Journal of Physics: Conference Series (2021), 012049, database is CAplus.

The gum resin of S. benzoin is a very important commodity in the world of industrialization and really needs the attention of the frankincense farmers. This is based on the many benefits of the plants which are only limited to livelihoods.The purpose of the research are to know the results of increasing the stability of the gum styrax benzoin with the addition of cosolvents. The identification of the components of secondary metabolites using phytochem. screening.The methodol. of the research is maceration the gum styrax benzoin ash with Etanol solvent until all samples are immersed and carried out in a glass bottle for three days. The research was continued with identification of the components of secondary metabolites using phytochem. screening. The findings of the research is anal. using phytochem. screening shows the secondary metabolites styrax benzoin such as alkaloids, flavonoid, tannin, saponin, and terpenoid. The limitations of the research is focuses on 3 variations in the Cosolvent of propylene glycol, polyethylene glycol and triethanolamine. The reserch have value specifically the gum styrax benzoin is used as the solubility of several pharmaceutical compounds

Journal of Physics: Conference Series published new progress about 68527-74-2. 68527-74-2 belongs to dioxole, auxiliary class Dioxolane,Benzene,Phenol,Ether, name is 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol, and the molecular formula is C44H28ClFeN4, Application of 2-Methoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Bantreil, Xavier published the artcileEnantioselective γ-lactam synthesis via palladium-catalyzed intramolecular asymmetric allylic alkylation, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Synlett (2009), 1441-1444, database is CAplus.

A Pd(0)-catalyzed intramol. allylic alkylation in the presence of chiral atropisomeric bidentate ligands, e.g., (R)-3,5-t-Bu-MeOBIPHEP, takes place in up to 92:8 er in agreement with DFT calculations and provides easy access to enantioenriched disubstituted γ-lactams. E.g., 2.5 mol% [Pd(η³-C₃H₅)Cl]₂ in CH₂Cl₂ was added to 7.5 mol% (R)-BINAP at room temperature to which 1 equivalent of MeO₂CCH₂C(O)B(Bn)CH₂CH:CHCH₂OAc in CH₂Cl₂, BSA and KOAc were successively added to give N-benzyl-3-carbomethoxy-4-vinyl-γ-lactam in 88% yield.

Synlett published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem

Bantreil, Xavier published the artcileγ- And δ-Lactams through Palladium-Catalyzed Intramolecular Allylic Alkylation: Enantioselective Synthesis, NMR Investigation, and DFT Rationalization, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, the publication is Chemistry – A European Journal (2011), 17(10), 2885-2896, S2885/1-S2885/122, database is CAplus and MEDLINE.

The Pd-catalyzed intramol. allylic alkylation of unsaturated amides to give γ- and δ-lactams has been studied in the presence of chiral ligands. Ligand (R)-3,5-tBu-MeOBIPHEP ((MeOBIPHEP = 6,6′-dimethoxybiphenyl-2,2-diyl)bis(diphenylphosphine)) afforded the best results and allowed the cyclization reactions to take place in up to 94:6 enantiomeric ratio. A model Pd-allyl complex has been prepared and studied through NMR spectroscopic anal., which provided insight into the processes responsible for the observed enantiomeric ratios. DFT studies were used to characterize the diastereomeric reaction pathways. The calculated energy differences were in good agreement with the exptl. observed enantiomeric ratios.

Chemistry – A European Journal published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, Recommanded Product: (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole.

Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem