Sedative effects of inhaled Perilla frutescens essential oils on mice was written by Ota, Yue;Ito, Michiho. And the article was included in Journal of Natural Medicines in 2021.SDS of cas: 607-91-0 This article mentions the following:
Perilla frutescens is an ingredient for cooking and for Japanese traditional medicine formulations. Essential oils extracted from P. frutescens are classified according to their composition, which are genetically regulated. Here, we extracted five types of essential oil from P. frutescens and studied their sedative activities. We grew P. frutescens strains that give oils of type PK, PA, PP, EK, and C, and extracted the essential oils by hydrodistillation We then measured the spontaneous locomotor activity of mice who had inhaled the oils in an open field test. All types of essential oil except the PK type decreased the spontaneous locomotor activity of mice. The EDs were 4.0 x 10-3 to 4.0 x 10-2 mg/cage (PA type), 4.0 x 10-4 mg/cage (PP type), 4.0 x 10-5 mg/cage (EK type), and 4.0 x 10-5 to 4.0 x 10-3 mg/cage (C type). Our results show that the essential oils of type PA, PP, EK, and C have a sedative effect. In the experiment, the researchers used many compounds, for example, 6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0SDS of cas: 607-91-0).
6-Allyl-4-methoxybenzo[d][1,3]dioxole (cas: 607-91-0) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.SDS of cas: 607-91-0
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem