New research progress on 29390-67-8 in 2021. Chemical research careers are more diverse than they might first appear, as there are many different reasons to conduct research and many possible environments. In an article, author is Kancharla, Suman, once mentioned the application of 29390-67-8, Recommanded Product: 29390-67-8, Name is Mono-(6-amino-6-deoxy)-β-cyclodextrin, molecular formula is C42H71NO34, molecular weight is 1133.9995, MDL number is MFCD03452964, category is dioxole. Now introduce a scientific discovery about this category.
In view of generatingnew compounds for future drug development, we have synthesized some 2-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxylquinazolin-4(3H)-one derivatives of 4,5-dimethoxy-2-nitrobenzamide (5), synthesized by the ortho-nitro acid 4 was converted to its acid chloride by using thionyl chloride, followed by treatment with ammonia (aq.) gave the substituted ortho-nitro benzanilide (5). 4,5-Dimethoxy-2-nitrobenzamide (5) react withbenzo(d)[1,3] dioxole-5-carbaldehyde (6a) in presence of SnCl2 center dot 2H(2)O in MeOH was heated to gave 2-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxylquinazolin-4(3H)-ones (7a-k). All the synthesized compounds were fully characterized on the basis of their detailed spectral studies and were evaluated for their antimicrobial activities in two Gram-positive bacteria (Staphylococcus aureus, Bacillus subtillis) and two Gram-negative bacteria (Echerichia coli and Pseudomonas aeuroginosa) and two fungi (Aspergillusniger and Aspergillusfumigatus) strains using Cup plate method
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Reference:
1,3-Benzodioxole – Wikipedia,
,Dioxole | C3H4O2 – PubChem