Cascade radical reaction of substrates with a carbon-carbon triple bond as a radical acceptor was written by Miyabe, Hideto;Asada, Ryuta;Takemoto, Yoshiji. And the article was included in Beilstein Journal of Organic Chemistry in 2013.Quality Control of 2-Bromomethyl-1,3-dioxolane This article mentions the following:
The limitation of hydroxamate ester as a chiral Lewis acid coordination moiety was demonstrated in an intermol. reaction involving a radical addition and sequential allylation processes. Next, the effect of hydroxamate ester was studied in the cascade addition-cyclization-trapping reaction of substrates with a carbon-carbon triple bond as a radical acceptor. When substrates with a methacryloyl moiety and a carbon-carbon triple bond as two polarity-different radical acceptors were employed, the cascade reaction proceeded effectively. A high level of enantioselectivity was also obtained by a proper combination of chiral Lewis acid and these substrates. In the experiment, the researchers used many compounds, for example, 2-Bromomethyl-1,3-dioxolane (cas: 4360-63-8Quality Control of 2-Bromomethyl-1,3-dioxolane).
2-Bromomethyl-1,3-dioxolane (cas: 4360-63-8) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Quality Control of 2-Bromomethyl-1,3-dioxolane
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem