Liu, Ren-Rong published the artcileEnantioselective alkynylation of N-sulfonyl α-ketiminoesters via a Friedel-Crafts alkylation strategy, SDS of cas: 503538-69-0, the publication is Chemical Communications (Cambridge, United Kingdom) (2017), 53(43), 5890-5893, database is CAplus and MEDLINE.
Enantioselective alkynylation of cyclic N-sulfonyl α-ketiminoesters I (R = H, 5-OMe, 7-Cl, etc.; R1 = Et, Me, i-Pr, n-Bu) with terminal alkynes R2CCH (R2 = C6H5, 3-FC6H4, 4-thien-2-yl, etc.) was developed by using an Ni(ClO4)2/(R)-DTBM-Segphos complex as a catalyst. A range of propargylic amides bearing quaternary stereocenters II was afforded in excellent enantioselectivities (up to 97% ee). Theor. studies revealed that this reaction proceeded via a Friedel-Crafts-type reaction pathway.
Chemical Communications (Cambridge, United Kingdom) published new progress about 503538-69-0. 503538-69-0 belongs to dioxole, auxiliary class (Atropisomeric Bisphosphine Ligands, name is (R)-5,5′-Bis(diphenylphosphino)-2,2,2′,2′-tetrafluoro-4,4′-bi-1,3-benzodioxole, and the molecular formula is C38H24F4O4P2, SDS of cas: 503538-69-0.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem