Little discovery in the laboratory: a new route for 22353-34-0

There are many compounds similar to this compound(22353-34-0)Reference of 5-Chloropyridin-3-amine. if you want to know more, you can check out my other articles. I hope it will help you,maybe you’ll find some useful information.

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Addressing species specific metabolism and solubility issues in a quinoline series of oral PDE4 inhibitors, published in 2010-01-01, which mentions a compound: 22353-34-0, Name is 5-Chloropyridin-3-amine, Molecular C5H5ClN2, Reference of 5-Chloropyridin-3-amine.

Species specific conversion of the lead PDE4 inhibitor 1 to the quinolone 3 was identified as the major route of metabolism in the cynomolgus monkey. Modification of the template to give the cinnoline 9 retained potency and selectivity, and greatly improved the pharmacokinetic profile in the cynomolgus monkey compared with 1. Addnl. SAR studies aimed at improving the solubility of 9 are also described.

There are many compounds similar to this compound(22353-34-0)Reference of 5-Chloropyridin-3-amine. if you want to know more, you can check out my other articles. I hope it will help you,maybe you’ll find some useful information.

Reference:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem