LeBouf, Ryan F. published the artcileHeadspace analysis for screening of volatile organic compound profiles of electronic juice bulk material, Name: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Analytical and Bioanalytical Chemistry (2018), 410(23), 5951-5960, database is CAplus and MEDLINE.
The use of electronic nicotine delivery systems continues to gain popularity, and there is concern for potential health risks from inhalation of aerosol and vapor produced by these devices. An anal. method was developed that provided quant. and qual. chem. information for characterizing the volatile constituents of bulk electronic cigarette liquids (e-liquids) using a static headspace technique. Volatile organic compounds (VOCs) were screened from a convenience sample of 146 e-liquids by equilibrating 1 g of each e-liquid in amber vials for 24 h at room temperature Headspace was transferred to an evacuated canister and quant. analyzed for 20 VOCs as well as tentatively identified compounds using a preconcentrator/gas chromatog./mass spectrometer system. The e-liquids were classified into flavor categories including brown, fruit, hybrid dairy, menthol, mint, none, tobacco, and other. 2,3-Butanedione was found at the highest concentration in brown flavor types, but was also found in fruit, hybrid dairy, and menthol flavor types. Benzene was observed at concentrations that are concerning given the carcinogenicity of this compound (max 1.6 ppm in a fruit flavor type). The proposed headspace anal. technique coupled with partition coefficients allows for a rapid and sensitive prediction of the volatile content in the liquid The technique does not require onerous sample preparation, dilution with organic solvents, or sampling at elevated temperatures Static headspace screening of e-liquids allows for the identification of volatile chem. constituents which is critical for identifying and controlling emission of potentially hazardous constituents in the workplace.
Analytical and Bioanalytical Chemistry published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Name: 2,2,4-Trimethyl-1,3-dioxolane.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem