Synthesis and AMPA-receptor modulating activity of benzodioxanecarboxylic and piperonylic acid derivatives was written by Lavrov, M. I.;Lapteva, V. L.;Grigor’ev, V. V.;Palyulin, V. A.;Bachurin, S. O.;Zefirov, N. S.. And the article was included in Pharmaceutical Chemistry Journal in 2012.Quality Control of Benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone This article mentions the following:
A series of amides of benzodioxane-6-carboxylic and piperonylic acids have been synthesized. Biol. studies showed that some of the synthesized compounds influence the central nervous system (in particular, AMPA receptors). Thus, at low concentrations (10-9-10-6 M), compound I potentiated the CA-induced AMPA-receptor current. Compound I at a dose of 0.1 mg/kg exhibited a stimulating influence on memory. In the experiment, the researchers used many compounds, for example, Benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone (cas: 34023-62-6Quality Control of Benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone).
Benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone (cas: 34023-62-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Quality Control of Benzo[d][1,3]dioxol-5-yl(piperidin-1-yl)methanone
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem