Synthesis of natural maleimides farinomaleins C-E and evaluation of their antifungal activity was written by Lahore, Santosh;Aiwale, Sachin T.;Sardi, Paola;Dallavalle, Sabrina. And the article was included in Tetrahedron Letters in 2014.Recommanded Product: 6413-10-1 The following contents are mentioned in the article:
A practical and convenient synthesis of naturally occurring farinomaleins C-E [C = I; (R)-/(S)-/(±)-D = II; E = III] was achieved starting from readily available Et 3-methyl-2-oxobutyrate and tri-Et phosphonoacetate. The key steps of the sequence included a Horner-Wadsworth-Emmons condensation to obtain the acid precursor farinomalein A and coupling with suitable alcs. to install the chain. The synthesis of farinomalein D has been achieved starting from (R)-isopropylideneglycerol on the basis of which the S configuration was assigned to the natural compound The antifungal activity of the synthesized compounds was evaluated against Cladosporium cladosporioides. This study involved multiple reactions and reactants, such as Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1Recommanded Product: 6413-10-1).
Ethyl 2-(2-methyl-1,3-dioxolan-2-yl)acetate (cas: 6413-10-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. 1,3-Benzodioxole can be synthesized from catechol with disubstituted halomethanes.Recommanded Product: 6413-10-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem