Kankaanpera, Alpo published the artcileStereochemistry of alkyl-1,3-dioxolanes and the kinetics of their hydrolysis, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane, the publication is Turun Yliopiston Julkaisuja, Sarja A: Physico-Mathematica-Biologica (1966), 68 pp., database is CAplus.
Twenty-three methyl substituted 1,3-dioxolanes (disregarding optical isomers) and 23 other substituted 1,3-dioxolanes were prepared for a kinetic study of their hydrolysis. The structures of 25 isomeric derivatives were deduced from kinetic data and, in some cases, the structures of the reagents used in the synthesis. The equilibrium constants of the interconversion of isomers indicate that the 1,3-dioxolane ring is non planar. The exptl. data can be accounted for if the ring has the shape of the half chair of cyclopentane, and one of the hetero atoms is located on the axis of symmetry. The kinetic data reveal that 1,3-dioxolane and its alkyl derivatives are hydrolyzed by the same mechanism as acyclic acetals. The reactions exhibit a number of special features not observed in previous studies of acetal hydrolysis. Structural factors affecting the rates are: polar effects of substituents which influence the strengths of the bonds broken in the rate determining stage, the eclipsing strain resulting from the interaction of substituents at positions 4 and 5 when the critical complex of the hydrolysis is approached, and steric effects due to the bending of substituents at position 2 toward the 1,3-dioxolane ring.
Turun Yliopiston Julkaisuja, Sarja A: Physico-Mathematica-Biologica published new progress about 1193-11-9. 1193-11-9 belongs to dioxole, auxiliary class Dioxolanes, name is 2,2,4-Trimethyl-1,3-dioxolane, and the molecular formula is C6H12O2, Recommanded Product: 2,2,4-Trimethyl-1,3-dioxolane.
Referemce:
https://en.wikipedia.org/wiki/1,3-Benzodioxole,
Dioxole | C3H4O2 – PubChem