Organotransition metal modified sugars Part 21. Synthesis of organometallic disaccharides bearing two monosaccharide moieties linked by a chromium carbene spacer was written by Janes, E.;Dotz, K. H.. And the article was included in Journal of Organometallic Chemistry in 2001.Category: dioxole This article mentions the following:
Organometallic disaccharides containing a chromium carbene spacer have been synthesized from tetramethylammonium acetyl(pentacarbonyl)chromate(-I) (1) in a two-step protocol. An acylation/alcoholysis sequence applying di(isopropylidene)-protected glucose, mannose, galactose and fructose afforded O-glycoside methylcarbene complexes 6-9 in 29-84% yield. Upon reaction with 1,2:3,4-di-O-isopropylidene-α-D-galacto-hexodiald-1,5-ose, activated by TiCl4, they undergo a trans-selective aldol condensation to give a 53-89% yield of chromium vinylcarbene O,C-disaccharides which are promising candidates for subsequent benzannulation, cyclopropanation, Diels-Alder- and Michael addition reactions. In the experiment, the researchers used many compounds, for example, (3aS,4S,6R,6aS)-6-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol (cas: 14131-84-1Category: dioxole).
(3aS,4S,6R,6aS)-6-((R)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol (cas: 14131-84-1) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Although benzodioxole is not particularly important, many related compounds containing the methylenedioxyphenyl group are bioactive, and thus are found in pesticides and pharmaceuticals.Category: dioxole
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem