On December 31, 1980, Garegg, Per J.; Samuelsson, Bertil published an article.Related Products of 38838-06-1 The title of the article was Novel reagent system for converting a hydroxy-group into an iodo-group in carbohydrates with inversion of configuration. Part 2. And the article contained the following:
Isolated primary and secondary hydroxy groups in carbohydrate derivatives were substituted by iodo-groups, with inversion of configuration, on treatment with either Ph3P, I2, and imidazole, or imidazole and 2,4,5-triiodoimidazole at elevated temperatures E.g., I (R = OH, R1 = H) with Ph3P, I2, and imidazole (PhMe, reflux, overnight) gave I (R = H, R1 = iodo) (67%). At lower temperature, primary hydroxy-groups were selectively replaced by iodo-groups. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Related Products of 38838-06-1
The Article related to iodination carbohydrate, imidazole triphenylphosphine iodine carbohydrate iodination, phenylphosphine imidazole iodine carbohydrate iodination, iodoimidazole carbohydrate substitution, epimerization carbohydrate substitution iodine, iodocarbohydrate and other aspects.Related Products of 38838-06-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem