On November 15, 1979, Garegg, Per J.; Samuelsson, Bertil published an article.Recommanded Product: 38838-06-1 The title of the article was Novel reagent system for converting a hydroxy group into an iodo group in carbohydrates with inversion of configuration. And the article contained the following:
Primary and secondary OH groups were converted into iodo groups, with inversion of configuration, by heating with Ph3P/iodine/imidazole (reagent A) or Ph3P/2,4,5-triiodoimidazole (reagent B) in PhMe at elevated temperature Iodine was introduced at the 2-position in hexopyranosides by these methods. E.g., Me 3,4,6-tri-O-benzyl-α-D-mannopyranoside gave 67 and 82% Me 3,4,6-tri-O-benzyl-2-deoxy-2-iodo-α-D-glucopyranoside by treatment with reagents A and B, resp. The experimental process involved the reaction of (3aS,4S,6R,6aR)-4-(Iodomethyl)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole(cas: 38838-06-1).Recommanded Product: 38838-06-1
The Article related to hydroxyl conversion iodo carbohydrate, iodination carbohydrate, Carbohydrates: Monosaccharides, Glycals and other aspects.Recommanded Product: 38838-06-1
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem