Synthesis of 2-(1,4-dioxaspiro[4.5]decan-6-yl)acrylamides from 2-acetylcyclohexanone via palladium-catalysed aminocarbonylation was written by Farkas, Roland;Petz, Andea;Kollar, Laszlo. And the article was included in Monatshefte fuer Chemie in 2015.Name: 1,4-Dioxaspiro[4.5]decane This article mentions the following:
6-(1-Iodovinyl)-1,4-dioxaspiro[4.5]decane, an iodoalkene obtained from 2-acetylcyclohexanone via ethylene ketal formation, hydrazone formation and iodination, was aminocarbonylated in the presence of a palladium-phosphine precatalyst. Systematic investigations revealed that 2-(1,4-dioxaspiro[4.5]decan-6-yl)acrylamides I [R1 = H; R2 = tBu, CH2CO2Me, CH(CH3)CO2Me, CH{CH(CH3)2}CO2Me; R1R2 = (CH2)5, (CH2)O(CH2)2, CH(CO2Me)(CH2)3] can be obtained in high yields via palladium-catalyzed aminocarbonylation. The influence of the amine nucleophiles and of the reaction conditions on the isolated yields was investigated. In the experiment, the researchers used many compounds, for example, 1,4-Dioxaspiro[4.5]decane (cas: 177-10-6Name: 1,4-Dioxaspiro[4.5]decane).
1,4-Dioxaspiro[4.5]decane (cas: 177-10-6) belongs to dioxole derivatives. Dioxoles, particularly fluorinated dioxoles, are used as co-monomers to make polymers that find use in forming protective coatings for chemical resistance. Dioxole functionalized metal-organic frameworks have also been recently reported.Name: 1,4-Dioxaspiro[4.5]decane
Referemce:
1,3-Benzodioxole – Wikipedia,
Dioxole | C3H4O2 – PubChem